Protective effect of glycine in mesenteric ischemia and reperfusion injury in a rat model

Journal of Vascular Surgery

Volumn 38, Issue 5, 2003, Pages 1113-1120

  Kallakuri, Sreedhar ^b   Ascher, Enrico ^a   Pagala, Murali ^b   Gade, Prasad ^b   Hingorani, Anil ^b   Scheinman, Marcel ^b   Mehraein, Khodadad ^b   Jacob, Theresa ^b  

^a MAIMONIDES MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CARBACHOL; GLYCINE; POTASSIUM;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; ELECTROSTIMULATION; HISTOPATHOLOGY; INTESTINE CONTRACTION; INTESTINE ISCHEMIA; INTESTINE MUCOSA; INTESTINE MUSCLE; INTESTINE VILLUS; INTESTINE WALL; MALE; MESENTERY ISCHEMIA; MORPHOMETRICS; MUSCLE ISOMETRIC CONTRACTION; NONHUMAN; PRIORITY JOURNAL; RAT; REPERFUSION INJURY; THICKNESS;

EID: 0242491581     PISSN: 07415214     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0741-5214(03)00939-X     Document Type: Article

References (29)

1. Kurland B, Brandt LJ, Delany HM. Diagnostic tests for intestinal ischemia. Surg Clin North Am 1992;72:1, 85-105.
2. Schneider JR, Foker JE, Macnab JR, Marquardt CA, Cronenwett JL. Glucagon effect on post ischemic recovery of intestinal energy metabolism. J Surg Res 1994;56:123-9.
3. Gangadharan SP, Wagner RJ, Cronenwett JL. Effect of intravenous glucagon on intestinal viability after segmental mesenteric ischemia. J Vasc Surg 1995;21:900-8.
4. Park PO, Gerdin B. Haglund U. Effects of a novel 21 aminosteroid or methylprednisolone in experimental total intestinal ischemia. Arch Surg 1994;129:857-60.
5. Mastaf NA, Yandi M, Albayrak L, Yildiz K. Effects of pentoxyfilline on the ischemia-reperfusion injury office intestine. Int Surg 1995;80:152-5.
6. Morris JB, Guerrero NH, Furth EE, Stellato TA. Somatostatin attenuates ischemic intestinal injury. Am J Surg 1993;165:676-80.
7. O'Donnel KA, Cary MG, Gheng S, Rossman JE, Azizkhan RG. Oxygenated intraluminal perfluorocarbons protect intestinal mucosa from I/R injury. J Pediatr Surg 1997;32:361-5.
8. Oldham KT, Guice KS, Gore D, Gourley WK, Lobe TE. Treatment of intestinal ischemia with oxygenated perfluorocarbons. Am J Surg 1987;153:291-4.
9. Ricci JL, Sloviter HA, Ziegler MM. Reduction of mortality utilizing intraluminal perfluorochemicals. Am J Surg 1985;149:84-90.
10. Weinberg JM, Davis JA, Abarzua M, Kiani T, Kunkel R. Protection by glycine of proximal tubules from injury due to inhibitors of mitochondrial ATP production. Am J Physiol 1990;258:C1127-40.
11. Mangino MJ, Murphy MK, Grabau GG, et al. Protective effects of glycine during hypothermic renal ischemia-reperfusion injury. Am J Physiol 1991;261:F841-8.
12. Nagatomi A, Sakadia I, Matsumura Y, Okita K. Cytoprotection by glycine against hypoxia induced injury in cultured hepatocytes. Liver 1997;172:57-62.
13. Ghong Z, Tones S, Thurman RG. Glycine minimizes reperfusion injury in a low flow, reflow liver perfusion model in the rat. Am J Physiol 1996;270:G332-8.
14. Werman R. Amino acids as central transmitters. In: Kopin IJ, editor. Neurotransmitters. Baltimore, Md: Williams & Wilkins; 1972. p 147-80.
15. Ogata T, Nakamura KY, Okumura TH, Kataoka K, Shibata T. Role of aspartate in ischemic spinal cord damage. J Orthop Res 1996;14:504-10.
16. Ascher E, Hanson JN, Cheng W, Hingorani A, Schineman M. Glycine preserves function and decreases necrosis in skeletal muscle undergoing ischemia and reperfusion injury. Surgery 2001;129:231-5.
17. Zhang W, Hahn RG. "Double toxicity" of glycine solution in the mouse. Br J Urol 1996;77:203-6.
18. Chiu CJ, McArdle AH, Brown R, et al. Intestinal mucosal lesion in low flow states: a morphological, hemodynamic and metabolic reappraisal. Arch Surg 1970;101:478-83.
19. Pagala M. An in vitro multi-muscle tension recording chamber [abstract]. FASEB J 1995;9:5471.
20. Hodgkin AL, Horowicz P. Potassium contractures in single muscle fibers. J Physiol 1960;153:386-403.
21. Taylor P. Cholinergic agonists. In: Gilman AG, Rail TW, Nies AS, Taylor P, editors. Goodman and Gilman's pharmacological basis of therapeutics. New York, NY: Pergamon Press; 1990. p 122-30.
22. Puglici KN, Whalen TV, Doolin EJ. Computer analyzed histology of ischemic injury to the gut. J Pediatr Surg 1995;30:839-44.
23. Guyton AC, Hall JE. Textbook of medical physiology. Philadelphia, Pa: Saunders; 1996. p 793-802.
24. Pagala M, Nandakumar NV, Namba T, Grob D. Effect of temperature on neuromuscular transmission and contractility of isolated rat skeletal muscles [abstract]. Fed Proc 1986;45:4445.
25. Guder WG, Wagner S, Wirthensohn G. Metabolic fuels along the nephron: pathways and intracellular mechanisms of interactions. Kidney Int 1986;29:41-5.
26. Weidemann MJ, Krebs HA. The fuel of respiration of rat kidney cortex. Biochem 1969;112:149-66.
27. Weinberg JM, Davies JA, Abarzus M, Rajan T. Cytoprotective effects glycine and glutathione against hypoxic injury to renal tubules. J Clin Invest 1987;80:1446-54.
28. Baines AD, Shaikh N, Ho P. Mechanisms of perfused kidney cytoprotection by alanine and glycine. Am J Physiol 1990;259:F80-7.
29. Weinberg JM, Venkatachalam MA, Garzo-Quintero R, et al. Structural requirements for protection by small amino acids against hypoxic injury in kidney proximal tubules. FASEB J 1990;4:3347-54.