Putative roles of the CNF2 and CDTIII toxins in experimental infections with necrotoxigenic Escherichia coli type 2 (NTEC2) strains in calves

Microbes and Infection

Volumn 5, Issue 13, 2003, Pages 1189-1193

  Van Bost, Sigrid ^a   Roels, Stefan ^b   Oswald, Eric ^c   Mainil, Jacques ^a  

^a UNIVERSITY OF LIÈGE   (Belgium)

^b VETERINARY AND AGROCHEMICAL RESEARCH CENTRE   (Belgium)

^c CEMAGREF   (France)

Author keywords

Cattle bacteria; Escherichia coli; Necrotoxigenicity

Indexed keywords

BACTERIAL TOXIN; PROTEIN CDTIII; PROTEIN CNF2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL STRAIN; BLOOD FLOW; CATTLE; CLINICAL FEATURE; COLOSTRUM; CONTROLLED STUDY; DIARRHEA; ENTEROBACTER INFECTION; ESCHERICHIA COLI; INOCULATION; INTESTINE INJURY; NONHUMAN; PATHOGENESIS; PATHOGENICITY; PLASMID; PRIORITY JOURNAL; WILD TYPE;

BOS TAURUS; ESCHERICHIA COLI;

EID: 0242485536     PISSN: 12864579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.micinf.2003.08.005     Document Type: Article

References (22)

1. Blanco M., Blanco J., Blanco J.E., Ramos J. Enterotoxigenic, verotoxigenic, and necrotoxigenic Escherichia coli isolated from cattle in Spain. Am. J. Vet. Res. 54:1993;1446-1451.
2. Caprioli A., Falbo V., Roda L.G., Ruggeri F.M., Zona C. Partial purification and characterization of an Escherichia coli toxic factor that induces morphological cell alterations. Infect. Immun. 39:1983;1300-1306.
3. De Rycke J., Gonzales E.A., Blanco J., Oswald E., Blanco M., Boivin R. Evidence for two types of cytotoxic necrotizing factor in human and animal clinical isolates of Escherichia coli. J. Clin. Microbiol. 28:1990;694-699.
4. De Rycke J., Guillot J.F., Boivin R. Cytotoxins in non-enterotoxigenic strains of Escherichia coli isolated from faeces of diarrheic calves. Vet. Microbiol. 15:1987;137-150.
5. Falbo V., Famiglietti M., Caprioli A. Gene block encoding production of cytotoxic necrotizing factor 1 and hemolysin in Escherichia coli isolates from extraintestinal infections. Infect. Immun. 60:1992;2182-2187.
6. Oswald E., De Rycke J., Guillot J.F., Boivin R. Cytotoxic effect of multinucleation in HeLa cell cultures associated with the presence of Vir plasmid in Escherichia coli strains. FEMS Microbiol. Lett. 58:1989;95-100.
7. Smith H.W. A search for transmissible pathogenic characters in invasive strains of Escherichia coli: the discovery of a plasmid-controlled lethal character closely associated, or identified with colicin V. J. Gen. Microbiol. 83:1974;95-111.
8. Mainil J., Gerardin J., Jacquemin E. Identification of the F17 fimbrial subunit- and adhesin-encoding (f17A and f17G) gene variants in necrotoxigenic Escherichia coli from cattle, pigs and humans. Vet. Microbiol. 73:2000;327-335.
9. Gerardin J., Lalioui L., Jacquemin E., Le Bouguénec C., Mainil J. The afa related gene cluster in necrotoxigenic and other Escherichia coli from animals belongs to the afa-8 variant. Vet. Microbiol. 76:2000;175-184.
10. Pérès S.Y., Marchés O., Daigle F., Nougareyde J.-P., Herault F., Tasca C., De Rycke J., Oswald E. A new cytolethal distending toxin (CDT) from Escherichia coli producing CNF2 blocks HeLa cell division in G2/M phase. Mol. Microbiol. 24:1997;1095-1107.
11. Oswald E., Sugai M., Labigne A., Wu H.C., Fiorentini C., Boquet P., O'Brien A.D. Cytotoxic necrotizing factor type-2 produced by virulent Escherichia coli modifies the small GTP binding proteins Rho involved in assembly of actin stress fibers. Proc. Natl. Acad. Sci. USA. 91:1994;3814-3818.
12. Comayras C., Tascas C., Pérès S.Y., Ducommun B., Oswald E., De Rycke J. Escherichia coli cytolethal distending toxin blocks the HeLa cell cycle at G2/M transition by preventing cdc2 protein kinase dephosphorylation and activation. Infect. Immun. 65:1997;5088-5095.
13. Elliott S.J., Srinivas S., John Albert M., Alam K., Robins-Browne R.M., Gunzburg S.T., Mee B.J., Chang B.J. Characterization of the roles of hemolysin and other toxins in enteropathy caused by alpha-hemolytic Escherichia coli linked to human diarrhea. Infect. Immun. 66:1998;2040-2051.
14. Fournout S., Dozois C.M., Odin M., Desautels C., Pérès S.Y., Hérault F., Daigle F., Segafredo C., Laffitte J., Oswald E., Fairbrother J.M., Oswald I.P. Lack of a role of cytotoxic necrotizing factor 1 toxin from Escherichia coli in bacterial pathogenicity and host cytokine response in infected germfree piglets. Infect. Immun. 68:2000;839-847.
15. Van Bost S., Roels S., Mainil J. Necrotoxigenic Escherichia coli type-2 invade and cause diarrhoea during experimental infection in colostrum- restricted newborn calves. Vet. Microbiol. 81:2001;315-329.
16. Oswald E., De Rycke J., Lintermans P., Van Muylen K., Mainil J., Daube G., Pohl P. Virulence factors associated with cytotoxic necrotizing factor type two in bovine diarrheic and septicemic strains of Escherichia coli. J. Clin. Microbiol. 29:1991;2522-2527.
17. second ed Sambrook J., Fritsch E.F., Maniatis T. Molecular cloning: a laboratory manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
18. Chandler M., Clerget M., Galas D.J. The transposition frequency of IS 1-flanked transposons is a function of their size. J. Mol. Biol. 154:1982;229-243.
19. Oswald E., Pohl P., Jacquemins E., Lintermans P., Van Muylens K., O'Brien A.D., Mainil J. Specific DNA probes to detect Escherichia coli strains producing cytotoxic necrotizing factor type-1 or type-2. J. Med. Microbiol. 40:1994;428-434.
20. Van Bost S., Bâbe M-H., Jacquemin E., Mainil J. Characteristics of necrotoxigenic Escherichia coli isolated from septicemic and diarrheic calves between 1958 and 1970. Vet. Microbiol. 82:2001;311-320.
21. Feldman D.B., Gupta B.N. Histopathologic changes in laboratory animals resulting from various methods of euthanasia. Lab. Anim. Sci. 26:1976;218-222.
22. Lara-Tajero M., Galan J.E. A bacterial toxin that controls cells cycle progression as a deoxyribonuclease I-like protein. Science. 290:2000;354-357.