Comparison of three outpatient regimens in the management of nausea and vomiting in pregnancy

Journal of Perinatology

Volumn 23, Issue 7, 2003, Pages 531-535

  Bsat, Fadi A ^a,b   Hoffman, Despina E ^a   Seubert, David E ^b  

^a BAYSTATE MEDICAL CENTER   (United States)

^b TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENDECTIN; DOXYLAMINE; ESTROGEN DERIVATIVE; HISTAMINE H1 RECEPTOR ANTAGONIST; METOCLOPRAMIDE; PETHIDINE; PHENOTHIAZINE DERIVATIVE; PLACEBO; PROCHLORPERAZINE; PROMETHAZINE; PYRIDOXINE;

ADULT; ANTIEMETIC ACTIVITY; ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFICACY; DRUG SAFETY; DYSTONIA; FEMALE; FIRST TRIMESTER PREGNANCY; HUMAN; MAJOR CLINICAL STUDY; MONOTHERAPY; NAUSEA AND VOMITING; OUTPATIENT CARE; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SEDATION; SIDE EFFECT; STATISTICAL SIGNIFICANCE; TARDIVE DYSKINESIA;

ADULT; ANTIEMETICS; DRUG THERAPY, COMBINATION; FEMALE; HUMANS; HYPEREMESIS GRAVIDARUM; METOCLOPRAMIDE; NAUSEA; PREGNANCY; PREGNANCY COMPLICATIONS; PROCHLORPERAZINE; PROMETHAZINE; PROSPECTIVE STUDIES; PYRIDOXINE; TREATMENT OUTCOME; VOMITING;

EID: 0242456064     PISSN: 07438346     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.jp.7210986     Document Type: Article

References (21)

1. Jewell D, Young G. Interventions for nausea and vomiting in early pregnancy. Cochrane Database Syst Rev 2002;CD000145.
2. Klebanoff MA, Koslowe PA, Kaslow R, et al. Epidemiology of vomiting in early pregnancy. Obstet Gynecol 1985;66:612-6.
3. Depue RH, Bernstein L, Ross RT, et al. Hyperemesis gravidarum in relation to estradiol levels, pregnancy outcome, and other maternal factors: a seroepidemiologic study. Am J Obstet Gynecol 1987;156:1137-41.
4. Nageotte MP, Briggs GG, Towers CV, et al. Droperidol and diphenhydramine in the management of hyperemesis gravidarum. Am J Obstet Gynecol 1996;174:1801-5; discussion 1805-6.
5. Sahakian V, Rouse D, Sipes S, et al. Vitamin B6 is effective therapy for nausea and vomiting of pregnancy: a randomized, double-blind placebo-controlled study. Obstet Gynecol 1991;78:33-6.
6. Briggs GG. A guideline for treating hyperemesis gravidarum. Contemporary OB/GYN 1997;42:70-9.
7. Attard CL, Kohli MA, Coleman S, et al. The burden of illness of severe nausea and vomiting of pregnancy in the United States. Am J Obstet Gynecol 2002;185:S220-7.
8. Prenatal care. In: Cunningham FG, Gant NF, Leveno KJ, Gilstrap III LC, Hankins GDV, Clark SL, editors. Williams Obstetrics, 20th edition. Stamford: Appleton & Lange; 1997. p. 227-50.
9. Gadsby R, Barnie-Adshead AM, Jagger C. A prospective study of nausea and vomiting during pregnancy. Br J Gen Pract 1993;43:245-8.
10. Soules MR, Hughes Jr CL, Garcia JA, et al. Nausea and vomiting of pregnancy: role of human chorionic gonadotropin and 17-hydroxyprogesterone. Obstet Gynecol 1980;55:696-700.
11. Goldzieher JW, Moses LE, Averkin E, et al. A placebo-controlled double-blind crossover investigation of the side effects attributed to oral contraceptives. Fertil Steril 1971;22:609-23.
12. Deuchar N. Nausea and vomiting in pregnancy: a review of the problem with particular regard to psychological and social aspects. Br J Obstet Gynaecol 1995;102:6-8.
13. Sherman PW, Flaxman SM. Nausea and vomiting of pregnancy in an evolutionary perspective. Am J Obstet Gynecol 2002;185:S190-7.
14. Willis RS, Morris AT, Newsom AA, et al. Clinical observations in treatment of nausea and vomiting in pregnancy with vitamin B1 and B6. A preliminary report. Am J Obstet Gynecol 1942;44:265-71.
15. Heller S, Salkeld RM, Korner WF. Vitamin B6 status in pregnancy. Am J Clin Nutr 1973;26:1339-48.
16. Niebyl JR, Goodwin TM. Overview of nausea and vomiting of pregnancy with an emphasis on vitamins and ginger. Am J Obstet Gynecol 2002;185:S253-5.
17. Vutyavanich T, Wongtra-ngan S, Ruangsri R. Pyridoxine for nausea and vomiting of pregnancy: a randomized, double-blind, placebo-controlled trial. Am J Obstet Gynecol 1995;173:881-4.
18. Van Thiel DH, Gavaler JS, Joshi SN, et al. Heartburn of pregnancy. Gastroenterology 1977;72:666-8.
19. Kumar D. In vitro inhibitory effect of progesterone on extrauterine human smooth muscle. Am J Obstet Gynecol 1962;84:1300.
20. Vella L, Francis D, Houlton P, et al. Comparison of the antiemetics metoclopramide and promethazine in labour. Br Med J (Clin Res Ed) 1985;290:1173-5.
21. Magee LA, Mazzotta P, Koren G. Evidence-based view of safety and effectiveness of pharmacologic therapy for nausea and vomiting of pregnancy (NVP). Am J Obstet Gynecol 2002;185:S256-61.