Neurologic complications after melarsomine dihydrochloride treatment for Dirofilaria immitis in three dogs

Journal of the American Veterinary Medical Association

Volumn 223, Issue 10, 2003, Pages 1456-1461+1434

  Hettlich, Bianca F ^a   Ryan, Kirk ^c   Bergman, Robert L ^a   Marks, Steven L ^d   Lewis, Barbara C ^a   Bahr, Anne ^b   Coates, Joan R ^a   Mansell, Joanne ^a   Barton, Claudia L ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

^b TEXAS A AND M UNIVERSITY   (United States)

^c Louisiana Veterinary Referral Center   (United States)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMOXICILLIN; BUTORPHANOL; CARPROFEN; CEFAZOLIN; CORTICOSTEROID; DEXAMETHASONE; DIAZEPAM; ENROFLOXACIN; MELARSAMINE; METHYLPREDNISOLONE ACETATE; METHYLPREDNISOLONE SODIUM SUCCINATE; OXYMORPHONE; PHENOXYBENZAMINE; PREDNISONE; RANITIDINE;

ARTICLE; ATAXIA; CARDIOPULMONARY ARREST; COMPUTER ASSISTED TOMOGRAPHY; DIFFERENTIAL DIAGNOSIS; DIROFILARIA IMMITIS; DISEASE COURSE; DOG DISEASE; EXERCISE; FECES INCONTINENCE; FEMALE; HISTOPATHOLOGY; LABORATORY TEST; MYELOGRAPHY; NEUROLOGIC DISEASE; NEUROLOGIC EXAMINATION; NONHUMAN; PARASITOSIS; PHYSICAL EXAMINATION; PHYSIOTHERAPY; POSTOPERATIVE CARE; POSTOPERATIVE PAIN; RESUSCITATION; SPINAL CORD TUMOR; SPINAL REFLEX;

ANIMALS; ARSENICALS; DIROFILARIA IMMITIS; DIROFILARIASIS; DOG DISEASES; DOGS; FEMALE; INJECTIONS, INTRAMUSCULAR; MALE; NERVOUS SYSTEM DISEASES; TRIAZINES;

CANIS FAMILIARIS; DIROFILARIA IMMITIS;

EID: 0242440370     PISSN: 00031488     EISSN: None     Source Type: Journal    
DOI: 10.2460/javma.2003.223.1456     Document Type: Article

References (21)

1. Rawlings CA. Heartworm disease in dogs and cats. Philadelphia: WB Saunders Co, 1986;5-7.
2. Blass CE, Holmes RA, Neer TM. Recurring tetraparesis attributable to a heartworm in the epidural space of a dog. J Am Vet Med Assoc 1989;194:787-788.
3. Shires PK, Turnwald GH, Qualls CW, et al. Epidural dirofilariasis causing paraparesis in a dog. J Am Vet Med Assoc 1982;180: 1340-1343.
4. Luttgen PJ, Crawley RR. Posterior paralysis caused by epidural dirofilariasis in a dog. J Am Anim Hosp Assoc 1981;17:57-59.
5. Frank JR, Nutter FB, Kyles AE, et al. Systemic arterial dirofilariasis in five dogs. J Vet Int Med 1997;11:189-194.
6. Patton CS, Garner FM. Cerebral infarction caused by heartworms (Dirofilaria immitis) in a dog. J Am Vet Med Assoc 1970;156: 600-605.
7. Cooley AJ, Clemmons RM, Gross TL. Heartworm disease manifested by encephalomyelitis and myositis in a dog. J Am Vet Med Assoc 1987;190:431-432.
8. Stuart BP, Hoss HE, Root CR, et al. Ischemic myopathy associated with systemic dirofilariasis. J Am Anim Hosp Assoc 1978;14: 36-39.
9. Slonka GF, Castleman W, Krum S. Adult heartworms in arteries and veins of a dog. J Am Vet Med Assoc 1977;170:717-719.
10. McCall JW, McTier T, Supakorndej N, et al. Further characterization of the sensitivity of several commercially available heartworm antigen test kits, in Proceedings. North Am Vet Conf 1994;8: 461-463.
11. McCall JW, Supakorndej N, McTier T, et al. Commercial heartworm antigen test kits detect infections with a single adult female worm but not those with numerous adult male worms only, in Proceedings. 38th Annu Meet Am Assoc Vet Parasitol 1993;36.
12. Hoskins JD, Hribernik TN, Kearney MT. Complications following thiacetarsamide sodium therapy in Louisiana dogs with naturally occurring heartworm disease. Cornell Vet 1985;75:531-539.
13. Rawlings CA, Raynaud J, Lewis RE, et al. Pulmonary thromboembolism and hypertension after thiacetarsamide vs melarsomine dihydrochloride treatment of Dirofilaria immitis infection in dogs. Am J Vet Res 1993;54:920-925.
14. Calvert CA. Indications for use of aspirin and corticosteroid hormones in the treatment of canine heartworm disease. Semin Vet Med Surg (Small Anim) 1987;2:78-84.
15. Dillon AR, Brawner WR, Hanranhan L. Influence of number of parasites and exercise on the severity of heartworm disease in dogs. In: Proceedings of the heartworm symposium '95. Batavia, III: American Heartworm Society, 1995;113.
16. Fukami N, Hagio M, Okano S, et al. Influence of exercise on recovery of dogs following heartworm adulticide treatment with melarsomine. In: Recent advances in heartworm diseases symposium '98. Batavia, III: American Heartworm Society, 1998; 225-227.
17. Dillon AR, Braund KG. Distal polyneuropathy after canine heartworm disease therapy complicated by disseminated intravascular coagulation. J Am Vet Med Assoc 1982;181:239-242.
18. Raynaud JP. Thiacetarsamide (adulticide) versus melarsomine (RM 340) developed as macrofilaricide (adulticide and larvicide) to cure canine heartworm infection in dogs. Ann Rech Vet 1992; 23:1-25.
19. Rawlings CA, McCall JW. Current uses and hazards of melarsomine. In: Kirk RE, ed. Current veterinary therapy XIII, Philadelphia: WB Saunders Co, 2000;787-790.
20. Keister DM, Dzimianski MT, McTier TL, et al. Dose selection and confirmation of RM340, a new filaricide for the treatment of dogs with immature and mature Dirofilaria immitis. In: Proceedings of the heartworm symposium '92. Batavia, III: American Heartworm Society, 1992;225-229.
21. McTier TL, McCall JW, Dzimianski MT, et al. Use of melarsomine dihydrochloride (RM 340) for adulticidal treatment of dogs with naturally acquired infections of Dirofilaria immitis and for clinical prophylaxis during reexposure for 1 year. Vet Parasitol 1994;55: 221-233.