Lack of association of interleukin-10 promoter region polymorphisms with Alzheimer's disease

Neuroscience Letters

Volumn 342, Issue 1-2, 2003, Pages 132-134

  Depboylu, Candan ^a   Du, Yansheng ^b   Müller, Ulrich ^c   Kurz, Alexander ^d   Zimmer, Reinhilde ^d   Riemenschneider, Matthias ^d   Gasser, Thomas ^e   Oertelf, Wolfgang H ^f   Klockgether, Thomas ^a   Dodel, Richard C ^a  

^a UNIVERSITY OF BONN   (Germany)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c JUSTUS LIEBIG UNIVERSITY   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF TÜBINGEN   (Germany)

^f PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Alzheimer's disease; Cytokine; Dementia; Inflammation; Interleukin; Polymorphism; Pro inflammatory

Indexed keywords

INTERLEUKIN 10;

ADULT; AGED; ALLELISM; ALZHEIMER DISEASE; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE FREQUENCY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; RISK; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 0242417473     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(03)00231-3     Document Type: Article

References (13)

1. Bales K.R., Du Y., Holtzman D., Cordell B., Paul S.M. Neuroinflammation and Alzheimer's disease: critical roles for cytokine/Abeta-induced glial activation, NF-kappaB, and apolipoprotein E. Neurobiol. Aging. 21:2000;427-432.
2. Crawley E., Kay R., Sillibourne J., Patel P., Hutchinson I., Woo P. Polymorphic haplotypes of the interleukin-10 5′ flanking region determine variable interleukin-10 transcription and are associated with particular phenotypes of juvenile rheumatoid arthritis. Arthritis Rheum. 42:1999;1101-1108.
3. Du Y., Dodel R.C., Eastwood B.J., Bales K.R., Gao F., Lohmuller F., Muller U., Kurz A., Zimmer R., Evans R.M., Hake A., Gasser T., Oertel W.H., Griffin W.S., Paul S.M., Farlow M.R. Association of an interleukin 1 alpha polymorphism with Alzheimer's disease. Neurology. 55:2000;480-483.
4. Griffin W.S., Sheng J.G., Roberts G.W., Mrak R.E. Interleukin-1 expression in different plaque types in Alzheimer's disease: significance in plaque evolution. J. Neuropathol. Exp. Neurol. 54:1995;276-281.
5. Hulkkonen J., Pertovaara M., Antonen J., Lahdenpohja N., Pasternack A., Hurme M. Genetic association between interleukin-10 promoter region polymorphisms and primary Sjogren's syndrome. Arthritis Rheum. 44:2001;176-179.
6. McKhann G., Drachman D., Folstein M., Katzman R., Price D., Stadlan E.M. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 34:1984;939-944.
7. Meyer M.R., Tschanz J.T., Norton M.C., Welsh-Bohmer K.A., Steffens D.C., Wyse B.W., Breitner J.C. APOE genotype predicts when - not whether - one is predisposed to develop Alzheimer disease. Nat. Genet. 19:1998;321-322.
8. Mok C.C., Lanchbury J.S., Chan D.W., Lau C.S. Interleukin-10 promoter polymorphisms in Southern Chinese patients with systemic lupus erythematosus. Arthritis Rheum. 41:1998;1090-1095.
9. Sheng J.G., Mrak R.E., Bales K.R., Cordell B., Paul S.M., Jones R.A., Woodward S., Zhou X.Q., McGinness J.M., Griffin W.S. Overexpression of the neuritotrophic cytokine S100beta precedes the appearance of neuritic beta-amyloid plaques in APPV717F mice. J. Neurochem. 74:2000;295-301.
10. Strle K., Zhou J.H., Shen W.H., Broussard S.R., Johnson R.W., Freund G.G., Dantzer R., Kelley K.W. Interleukin-10 in the brain. Crit. Rev. Immunol. 21:2001;427-449.
11. Tanzi R.E., Bertram L. New frontiers in Alzheimer's disease genetics. Neuron. 32:2001;181-184.
12. Turner D.M., Williams D.M., Sankaran D., Lazarus M., Sinnott P.J., Hutchinson I.V. An investigation of polymorphism in the interleukin-10 gene promoter. Eur. J. Immunogenet. 24:1997;1-8.
13. The ICD-10 Classification of Mental and Behavioural Disorders: Clinical Descriptions and Diagnostic Guidelines. 1992;World Health Organization, Geneva.