Hydrodynamic and spectroscopic studies of substrate binding to human recombinant deoxycytidine kinase

Nucleosides, Nucleotides and Nucleic Acids

Volumn 22, Issue 2, 2003, Pages 175-192

  Mani, Rajam S ^a   Usova, Elena V ^b   Eriksson, Staffan ^b   Cass, Carol E ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

Author keywords

Circular dichroism; Deoxycytidine kinase; Fluorescence spectroscopy; Gemcitabine

Indexed keywords

ADENOSINE TRIPHOSPHATE; DEOXYCYTIDINE KINASE; GEMCITABINE; NUCLEOSIDE DERIVATIVE; RECOMBINANT ENZYME;

ALPHA HELIX; ARTICLE; CIRCULAR DICHROISM; DRUG METABOLISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; ENZYME SUBSTRATE COMPLEX; HYDRODYNAMICS; PROTEIN DENATURATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; SPECTROFLUOROMETRY; ULTRAVIOLET SPECTROSCOPY;

ADENOSINE TRIPHOSPHATE; BINDING SITES; CHROMATOGRAPHY, GEL; CIRCULAR DICHROISM; DEOXYCYTIDINE; DEOXYCYTIDINE KINASE; DIMERIZATION; DNA, COMPLEMENTARY; HUMANS; LIGANDS; PROTEIN STRUCTURE, SECONDARY; RECOMBINANT PROTEINS; SPECTROPHOTOMETRY, ULTRAVIOLET; SUBSTRATE SPECIFICITY; ULTRACENTRIFUGATION; URIDINE TRIPHOSPHATE;

EID: 0242416537     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-120019513     Document Type: Article

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