Parallelism and dissociation in the actions of an Aroclor 1260-based transformer fluid on testicular androgenesis and antioxidant enzymes

Toxicology

Volumn 194, Issue 1-2, 2003, Pages 65-75

  Andric, Nebojsa L ^a   Andric, Silvana A ^a   Zoric, Sonja N ^a   Kostic, Tatjana S ^a   Stojilkovic, Stanko S ^b   Kovacevic, Radmila Z ^a  

^a UNIVERSITY OF NOVI SAD   (Serbia)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

Author keywords

Catalase; Glutathione; Glutathione peroxidase; Polychlorinated biphenyls; Pyralene; Testosterone; Transferase

Indexed keywords

ALKENE DERIVATIVE; ANDROGEN; ANTIOXIDANT; AROCLOR; CATALASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; ISOENZYME; PYRALENE; UNCLASSIFIED DRUG;

ANDROGENESIS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DISSOCIATIVE DISORDER; ENZYME ACTIVITY; IN VITRO STUDY; INJECTION; LEYDIG CELL; LIPID PEROXIDATION; LIQUID; LIVER; MALE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; RAT; TESTIS; TOXICITY;

EID: 0242410663     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2003.08.002     Document Type: Article

References (44)

1. Andric S.A., Kostic T.S., Dragisic S., Andric N.Lj., Stojilkovic S.S., Kovacevic R.Z. Acute effects of polychlorinated biphenyl-containing and free transformer fluids on rat testicular steroidogenesis. Env. Health Persp. 108:2000a;955-959.
2. Andric S.A., Kostic T.S., Stojilkovic S.S., Kovacevic R.Z. Inhibition of rat testicular androgenesis by a polychlorinated biphenyl mixture Aroclor 1248. Biol. Reprod. 62:2000;1882-1888.
3. Andric, S.A., Kostic, S.S., Dragisic, S., Stojilkovic, S.S., Kovacevic, R.Z., 2001. Acute in vivo and in vitro effects of Aroclors on rat testicular steroidogenesis. In: Robertson, L.W., Hansen, L.G. (Eds.), Recent Advances in the Environmental Toxicology and Health Effects. The University Press of Kentucky, pp. 303-307.
4. Andric, N., Andric, S., Zoric, S., Kostic, T., Kovacevic, R., 2002. Effects of commercial PCB mixture on rat testicular enzyme activities. In: Proceedings of the 6th International Symposium Interdisciplinary Regional Research (Hungary, Romania, Yugoslavia). University of Novi Sad, Yugoslavia, CD 0103, pp. 1-5.
5. Andric S.A., Andric N.L., Zoric S.N., Kostic T.S., Kovacevic R.Z. Effects of polychlorinated biphenyl-containing and free transformer fluids on testicular enzyme activities. Fresenius Environ. Bull. 12:2003;245-249.
6. Bradford M.M. A rapid and sensitive method for quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal. Biochem. 72:1976;248-254.
7. Bush B., Bennet A.H., Snow J.T. Polychlorobiphenyl congeners, p,p′-DDE and sperm function in humans. Arch. Environ. Contam. Toxicol. 15:1986;333-341.
8. Claiborne, A., 1984. In: Greenwald, R.A. (Eds.), CRC Handbook of Methods for Oxygen Radical Research, Catalase Activity. CRC Press, Boca Raton, FL, pp. 283-284.
9. Cooke, P.S., Sato, T., Buchanan, D.L., 2001. In: Robertson, L.W., Hansen, L.G. (Eds.), Recent Advances in the Environmental Toxicology and Health Effects. P450 Enzymes: Disruption of Steroid Hormone Signaling by PCBs. The University Press of Kentucky, pp. 257-263.
10. DiBiasio K.W., Silvia M.H., Shull L.R., Overstreet J.W., Hammock B.D., Miller M.G. Xenobiotic metabolizing enzyme activities in rat, mouse, monkey, and human testes. Drug Metab. Dispos. 19:1991;227-232.
11. Dikshith T.S.S., Rockwood W., Abraham R., Coulston F. Effects of a polychlorinated biphenyl (Aroclor 1254) on rat testis. Exp. Mol. Pathol. 22:1975;376-385.
12. Emmet, E.A., Maroni, M., Schmith, J.M., Levin, B.K., Jeffer, Y.S.J., 1988. Studies of transformer repair workers exposed to PCBs I. Study design, PCB concentrations, questionnaire, and clinical examination results. Am. J. Ind. Med. 13 (4), 415-427.
13. Fadhel Z., Lu Z., Robertson L.W., Glauert H.P. Effect of 3,3′,4,4′-tetrachlorobiphenyl and 2,2′,4,4′,5,5′- hexachlorobiphenyl on the induction of hepatic lipid peroxidation and cytochrome P-450 associated enzyme activities in rats. Toxicology. 175:2002;15-25.
14. Faqi A.S., Dalsenter P.R., Mathar W., Heinrich-Hirsh B., Chahoud I. Reproductive toxicity and tissue concentrations of 3,3′,4,4′- tetrachlorobiphenyl (PCB 77) in male adult rats. Hum. Exp. Toxicol. 17:1998;151-156.
15. Fouchecourt M.O., Riviere J.L. Activities of cytochrome P450-dependent monooxygenases and antioxidant enzymes in different organs of Norway rats (Rattus norvegicus) inhabiting reference and contaminated sites. Chemosphere. 31:1995;4375-4386.
16. Frame G.M., Cochran J.W., Bowadt S.S. Complete PCB congener distributions for 17 Aroclor Mixtures determined by 3 HRGC system optimized for comprehensive, quantitative, congener specific analysis. J. High Resolut. Chromatogr. 19:1996;657-668.
17. Griffith O.W. Determination of glutathione and glutathione disulfide using glutathione reductase and 2-vinyl pyridine. Anal. Biochem. 106:1980;207-212.
18. Guo Y.L., Yu M.L., Hsu C.C., Rogan W.J. Chloracne, goiter, arthritis, and anemia after polychlorinated biphenyl poisoning 14-year follow-up of the Taiwan Yucheng cohort. Env. Health Persp. 107:1999;715-719.
19. Habig W.H., Pabst M.J., Jakoby W.B. Gluthatione-S-transferases. J. Biol. Chem. 249:1974;7130-7139.
20. Harris M., Zacharewski T., Safe S. Comparative potencies of Aroclors 1232, 1242, 1248, 1254 and 1260 in male Wistar rats - assessment of the toxic equivalency fact or (TEF) approach for polychlorinated biphenyls (PCBs). Fundam. Appl. Toxicol. 20:1993;456-463.
21. Hassoun E.Z., Wang H., Abushaban A. Induction of oxidative stress in the tissues of rats after chronic exposure to TCDD, 2,3,4,7,8- pentachlorodibenzofuran and 3,3′,4,4′,5-pentachlorobiphenyl. J. Toxicol. Environ. Health A. 65:2002;825-842.
22. Hori M., Kondo H., Ariyoshi N., Yamada H., Hiratsuka A., Watabe T., Oguri K. Changes in the hepatic glutathione peroxidase redox system produced by coplanar polychlorinated biphenyls in Ah-responsive and less-responsive strains of mice: mechanism and implications for toxicity. Environ. Toxicol. Pharamacol. 3:1997;267-275.
23. Hsu P.C., Li M.H., Guo Y.L. Postnatal exposure of 2,2′,3,3′, 4,6′-hexachlorobiphenyl and 2,2′,3,4′,5′,6- hexachlorobiphenyl on sperm function and hormone levels in adult rats. Toxicology. 187:2003;117-126.
24. Kleeman J.M., Moore R.W., Peterson R.E. Inhibition of testicular steroidogenesis in 2,3,7,8,-tetrachlorodibenzo-p-dioxin treated rats: evidence that the key lesion occurs prior to or during pregnenolone formation. Toxicol. Appl. Pharmacol. 106:1990;112-125.
25. Kostic T.S., Andric S.A., Maric D., Kovacevic R.Z. Inhibitory effects of stress-activated nitric oxide on antioxidant enzymes and testicular steroidogenesis. J. Steroid Biochem. Molec. Biol. 75:2000;299-306.
26. Latchoumycandane C., Chitra K.C., Mathur P.P. The effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin on the antioxidant system in mitochondrial and microsomal fractions of rat testis. Toxicology. 171:2002;127-135.
27. Machala M., Neca J., Drabek P., Ulrich R., Sabatova V., Neyveda K., Raszyk J., Gajduskova V. Effects of chronic exposure to PCBs on cytochrome P450 systems and steroidogenesis in liver and testis of bulls (Bos taurus). Comp. Biochem. Physiol. Part A. 120:1998;65-70.
28. Madra S., Mann F., Francis J.E., Manson M.M., Smith A.G. Modulation by iron of hepatic microsomal and nuclear cytochrome P450, and cytosolic glutathione-S-transferase and peroxidase in C57BL/10ScSn mice induced with polychlorinated biphenyls (Aroclor 1254). Toxicol. Appl. Pharmacol. 136:1996;79-86.
29. Mandal P.K., McDaniel L.R., Prough R.A., Clark B.J. 7,12-dimethylbenz[a]- anthracene inhibition of steroid production in MA-10 mouse Leydig cells is not directly linked to induction of CYP1B1. Toxicol. Appl. Pharmacol. 175:2001;200-208.
30. Misra H.P., Fridovich I. The generation of superoxid radicals during autooxidation of hemoglobin. J. Biol. Chem. 247:1972;69600-69620.
31. Murray M., Reidy G.F. Selectivity in the inhibition of mammalian cytochromes P-450 by chemical agents. Pharmacol. Rev. 42:1990;85-101.
32. Ngui J.S., Bandiera S.M. Induction of hepatic CYP2B is more sensitive indicator of exposure to Aroclor 1260 than CYP1A in male rats. Toxicol. Appl. Pharmacol. 161:1999;160-170.
33. Otto S., Bhattacharyya K.K., Jefcoate C. Polycyclic aromatic hydrocarbon metabolism in rat adrenal, ovary, and testis microsomes is catalyzed by the same novel cytochrome P450 (P450RAP). Endocrinology. 131:1992;3067-3076.
34. Paglia D.E., Valentine N.W. Studies on qualitative and quantitative characterization of erythrocyte glutathione peroxidases. J. Lab. Clim. Med. 70:1967;74-77.
35. Peltola V., Mantyla E., Huhtaniemi I., Ahotupa M. Lipid peroxidation and antioxidant enzymes activities in the rat testis after cigarette smoke inhalation or administration of polychlorinated biphenyls or polychlorinated naphthalene's. J. Androl. 15:1994;353-361.
36. Peltola V., Huhtaniemi I., Metsa-Ketela T., Ahotupa M. Induction of lipid peroxidation during steroidogenesis in rat testis. Endocrinology. 137:1996;105-112.
37. Rozati R., Reddy P.P., Reddanna P., Mujtaba R. Role of environmental estrogens in the deterioration of male factor fertility. Fertil. Steril. 78:2002;1187-1194.
38. Sanders O.T., Zepp R.L., Kirkpatrick R.L. Effect of PCB ingestion on sleepindg times, organ weights, food consumption, serum corticosterone and survival in albino mice. Bull. Environ. Contam. Toxicol. 12:1974;394-399.
39. Schlezinger J.J., White R.D., Stegeman J.J. Oxidative inactivation of cytochrome P4501A (CYP1A) stimulated by 3,3′,4,4′- tetrachlorobiphenyl: production of reactive oxygen by vertebrate CYP1As. Mol. Pharmacol. 56:1999;588-597.
40. Seng J.E., Gandy J., Turturro A., Lipman R., Bronson R.T., Parkinson A., Johnson W., Hart R.W., Leakey J.E.A. Effects of caloric restriction on expression of testicular cytochrome P450 enzymes associated with the metabolic activation of carcinogens. Arch. Biochem. Biophys. 335:1996;42-52.
41. Slater T.F. Overview of methods for detecting lipid peroxidation. Modification of methods for detecting lipid peroxidation. Methods Enzymol. 105:1984;283-293.
42. Twaroski T., O'Brien M.L., Larmonier N., Glauert H.P., Robertson L.W. Polychlorinated biphenyl-induced effects on metabolic enzymes AP-1 binding, vitamin E, and oxidative stress in rat liver. Toxicol. Appl. Pharmacol. 171:2001a;85-93.
43. Twaroski, T.P., O'Brien, M.L., Robertson, L.W., 2001b. In: Robertson, L.W., Hansen, L.G. (Eds.), Recent Advances in the Environmental Toxicology and Health Effects. Effects of PCB 77 (3,3′,4,4′-Tetrachlorobiphenyl) on Glutathione Peroxidase Activity and Regulatory Mechanisms. The University press of Kentucky, pp. 317-319.
44. Twaroski T.P., O'Brien M.L., Robertson L.W. Effects of selected polychlorinated biphenyl (PCB) congener on hepatic glutathione, glutathione-related enzymes, and selenium status: implications for oxidative stress. Biochem. Pharmacol. 62:2001;273-281.