Autolysis of Penicillium chrysogenum - A Holistic Approach

Indian Journal of Biotechnology

Volumn 2, Issue 3, 2003, Pages 293-301

  Pócsi, István ^a   Pusztahelyi, Tünde ^a   Sámi, László ^a   Emri, Tamás ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Ageing; Apoptosis; Autolysis; Chitinase; Fragmentation; Respiration; Vacuolation

Indexed keywords

BETA LACTAM; CHITINASE; CYANIDE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROLASE; REACTIVE OXYGEN METABOLITE;

AGING; APOPTOSIS; AUTOLYSIS; BACTERIUM CULTURE; BIOTECHNOLOGY; CELL DEATH; CELL RESPIRATION; CELL VACUOLE; CELL VIABILITY; CONIDIUM; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME SYNTHESIS; EUKARYOTE; FUNGAL METABOLISM; FUNGAL MORPHOLOGY; FUNGUS; FUNGUS GROWTH; FUNGUS HYPHAE; GENOME; GROWTH CURVE; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; OXYGEN TENSION; PENICILLIUM CHRYSOGENUM; PROTEIN PROCESSING; REVIEW; SIGNAL TRANSDUCTION; STRESS;

BACTERIA (MICROORGANISMS); EUKARYOTA; FUNGI; PENICILLIUM; PENICILLIUM CHRYSOGENUM;

EID: 0242390539     PISSN: 09725849     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (64)

1. Adams T H et al, 1998. Asexual sporulation in Aspergillus nidulans. Microb Mol Biol Rev, 62, 35-54.
2. Bottone E J et al, 1998. Evidence of self-inhibition by filamentous fungi accounts for unidirectional hyphal growth in colonies. Can J Microbiol, 44, 390-393.
3. Christensen. L H et al, 1994. A robust liquid chromatographic method for measurement of medium components during penicillin fermentations. Anal Chim Acta, 296, 51-62.
4. Cooper C R & Haycocks N G, 2000. Penicillium marneffei: An insurgent species among the penicillia. J Eukaryot Microbiol, 47, 24-28.
5. Coppola S & Ghibelli L, 2000. GSH extrusion and the mitochondrial pathway of apoptotic signalling. Biochem Soc Trans, 28, 56-61.
6. Dufour E et al, 2000. A causal link between respiration and senescence in Podospora anserina. Proc Natl Acad Sci USA, 97, 4138-4143.
7. 2-stress conditions: The role of Yap1p in cell proliferation control in yeast. Mol Microbiol, 36, 830-845.
8. Elskens M T et al, 1991. Glutathione as an endogenous sulphur source in the yeast Saccharomyces cerevisiae. J Gen Microbiol, 137, 637-644.
9. Emri T et al, 1997. Glutathione metabolism and protection against oxidative stress caused by peroxides in Penicillium chrysogenum. Free Rad Biol Med, 23, 809-814.
10. Emri T et al, 1998. Changes in the glutathione (GSH) metabolism of Penicillium chrysogenum grown on different nitrogen, sulphur and carbon sources. J Basic Microbiol, 38, 3-8.
11. Emri T et al, 1999. Analysis of the oxidative stress response of Penicillium chrysogenum to menadione. Free Rad Res, 30, 125-132.
12. Frese D & Stahl U, 1992. Oxidative stress and ageing in the fungus Podospora anserina. Mech Ageing Dev, 65, 277-288.
13. Fröhlich K U & Madeo F, 2000. Apoptosis in yeast-A monocellular organism exhibits altruistic behaviour. FEBS Lett, 473, 6-9.
14. Gasch A P et al, 2000. Genomic expression programs in the response of yeast cells to environmental changes. Mol Biol Cell, 11, 4241-4257.
15. Gooday G W et al, 1992. What are the roles of chitinases in the growing fungus? FEMS Microbiol Lett, 100, 387-392.
16. Gooday G W, 1997. The many uses of chitinases in nature. Chitinase Chitosan Res, 3, 233-243.
17. Hansberg W & Aguirre J, 1990. Hyperoxidant states cause microbial cell differentiation by cell isolation from dioxygen. J Theor Biol, 142, 201-221.
18. Hansberg W et al, 1993. Reactive oxygen species associated with cell differentiation in Neurospora crassa. Free Rad Biol Med, 14, 287-293.
19. Harman D, 1993. Free radical involvement in aging. Drugs Aging, 3, 60-80
20. Harvey L M et al, 1998. Autolysis in batch cultures of Penicillium chrysogenum at varying agitation rates. Enzyme Microbial Technol, 22, 446-458.
21. Henriksen C M et al, 1997. Influence of the dissolved oxygen concentration on the penicillin biosynthetic pathway in steady-state cultures of Penicillium chrysogenum. Biotechnol Prog, 13, 776-782.
22. Ho C S & Smith M D, 1986. Morphological alterations of Penicillium chrysogenum caused by carbon dioxide. J Gen Microbiol, 132, 3479-3484.
23. Igual J C et al, 1996. Coordinated regulation of gene expression by the cell cycle transcription factor SWI4 and the protein kinase C AMP kinase pathway for yeast cell integrity. EMBO J, 15, 5001-5013.
24. Jakubowski W et al, 2000. Oxidative stress during aging of stationary cultures of the yeast Saccharomyces cerevisiae. Free Rad Biol Med, 28, 659-664.
25. Ju L K et al, 1991. Effects of carbon dioxide on the rheological behavior and oxygen transfer in submerged penicillin fermentations. Biotechnol Bioeng, 38, 1223-1232.
26. Jürgensen C W et al, 2001. Glutathione metabolism and dimorphism in Aureobasidium pullulans. J Basic Microbiol, 41, 131-137.
27. Jüsten P et al, 1998. Dependence of Penicillium chrysogenum growth, morphology, vacuolation, and productivity in fedbatch fermentations on impeller type and agitation intensity. Biotechnol Bioeng, 59, 762-775.
28. Karaffa L et al, 2001. Cyanide-resistant alternative respiration is strictly correlated to intracellular peroxide levels in Acremonium chrysogenum. Free Rad Res, 34, 405-416.
29. Kreiner M et al, 2003. Morphological and enzymatic responses of a recombinant Aspergillus niger to oxidative stressors in chemostat cultures. J Biotechnol, 100, 251-260.
30. Laun P et al, 2001. Aged mother cells of Saccharomyces cerevisiae show markers of oxidative stress and apoptosis. Mol Microbiol, 39, 1166-1173.
31. Lev S et al, 1999. A mitogen-activated protein kinase of the com leaf pathogen Cochliobolus heterostrophus is involved in conidiation, appressorium formation, and pathogenicity: Diverse roles for mitogen-activated protein kinase homology in foliar pathogens. Proc Natl Acad Sci USA, 96, 13542-13547.
32. Lorin S et al, 2001. Overexpression of the alternative oxidase restores senescence and fertility in a long-lived respiration-deficient mutant of Podospora anserina. Mol Microbiol, 42, 1259-1267.
33. Madeo F et al, 2002. Apoptosis in yeast: A new model system with applications in cell biology and medicine. Curr Genet, 41, 208-216.
34. McIntyre M et al, 1999. Response of Penicillium chrysogenum to oxygen starvation in glucose- and nitrogen-limited chemostat cultures. Enzyme Microb Technol, 25, 447-454.
35. McIntyre M et al, 2000. Role of proteases in autolysis of Penicillium chrysogenum chemostat cultures in response to nutrient depletion. Appl Microbiol Biotechnol, 53, 235-242.
36. McNeil B et al, 1998. Measurement of autolysis in submerged batch cultures of Penicillium chrysogenum. Biotechnol Bioeng, 57, 297-305.
37. Mehdi K & Penninckx M J, 1997. An important role of glutathione and y-glutamyltranspeptidase in the supply of growth requirements during nitrogen starvation of the yeast Saccharomyces cerevisiae. Microbiology, 143, 1885-1889.
38. Natsume M & Marumo S, 1984. Arthrospore-inducing substances from Acremonium chrysogenum which stimulate cephalosporin C production, Agric Biol Chem, 48, 567-569.
39. Nestelbacher R et al, 2000. The influence of oxygen toxicity on yeast mother cell-specific aging. Exp Gerontol, 35, 63-70.
40. Paul G C et al, 1994. Hyphal vacuolation and fragmentation in Penicillium chrysogenum, Biotechnol Bioeng, 44, 655-660.
41. Penninckx M J, 2000, A short review on the role of glutathione in the response of yeasts to nutritional, environmental, and oxidative stresses. Enzyme Microb Technol, 26, 737-742.
42. Pócsi I et al, 1993. The formation of N-acetyl-β -D-hexosaminidase is repressed by glucose in Penicillium chrysogenum. J Basic Microbiol, 33, 259-267.
43. Pócsi I et al, 2000. Allosamidin inhibits the fragmentation and autolysis of P. chrysogenum, in Advances in Chitin Science, edited by M G Peter, A Domard & R A A Muzzarelli, Vol 4. University of Potsdam, Potsdam. Pp 558-564.
44. Priede M A et al, 1997. Control of the production of individual fusicoccins at different dissolved oxygen concentrations. World J Microbiol Biotechnol, 13, 665-670.
45. Pusztahelyi T et al, 1997a. Ageing of Penicillium chrysogenum cultures under carbon starvation. I: Morphological changes and secondary metabolite production. Biotechnol Appl Biochem, 25, 81-86.
46. Pusztahelyi T et al, 1997b. Ageing of Penicillium chrysogenum cultures under carbon starvation. II: Protease and N-acetyl-β-D-hexosaminidase production. Biotechnol Appl Biochem, 25, 87-93.
47. Reichard U et al, 2000. Disruption of the gene which encodes a serodiagnostic antigen and chitinase of the human fungal pathogen Coccidioides immitis. Infect Immun, 68, 5830-5838.
48. Roze L V & Linz J E, 1998. Lovastatin triggers apoptosis-like cell death process in the fungus Mucor racemosus. Fungal Gen Biol, 25, 119-133.
49. Rozén S et al, 1999. The Aspergillus nidulans sfaD gene encodes a G protein β subunit that is required for normal growth and repression of sporulation. EMBO J, 18, 5592-5600.
50. Ruijter G J G et al, 2002. Production of organic acids by fungi, in The Mycota, edited by K Esser & J W Bennett, Vol X, Springer-Verlag, Berlin. Pp 213-230.
51. Sámi L et al, 2001a. Autolysis and ageing of Penicillium chrysogenum cultures under carbon starvation: Glutathione metabolism and formation of reactive oxygen species. Mycol Res, 105, 1246-1250.
52. Sámi L et al, 2001b. Autolysis and ageing of Penicillium chrysogenum cultures under carbon starvation: Chitinase production and antifungal effect of allosamidin. J Gen Appl Microbiol, 47, 201-211.
53. Sámi L, Karaffa L, Emri T & Pócsi I, 2003. Autolysis and ageing of Penicillium chrysogenum under carbon starvation: Respiration and glucose oxidase production. Acta Microbiol Immunol Hung, in press.
54. Sándor E et al, 1998. Allosamidin inhibits the fragmentation of Acremonium chrysogenum but does not influence the cephalosporin-C production of the fungus. FEMS Microbiol Lett, 164, 231-236.
55. Shimizu K & Keller N P, 2001. Genetic involvement of a cAMP-dependent protein kinase in a G protein signaling pathway regulating morphological and chemical transitions in Aspergillus nidulans. Genetics, 157, 591-600.
56. Skulachev V P, 2000. Mitochondria in the programmed death phenomena; a principle of biology: "It is better to die than to be wrong". IUBMB Life, 49, 365-373.
57. Skulachev V P, 2001. The programmed death phenomena, ageing, and the Samurai law of biology. Exp Gerontol, 36, 995-1024.
58. Takaya N et al, 1998. Cloning and charaterization of a chitinase-encoding gene (chiA) from Aspergillus nidulans, disruption of which decreases germination frequency and hyphal growth. Biosci Biotechnol Biochem, 62, 60-65.
59. Thevelein J M & de Winde J H, 1999. Novel sensing mechanism and targets for the cAMP-protein kinase: A pathway in the yeast Saccharomyces cerevisiae. Mol Microbiol, 33, 904-918.
60. th Int Mycol Congr, Int Mycol Congr, Jerusalem. P 103.
61. Toledo I et al, 1995. Redox imbalance at the start of each morphogenetic step of Neurospora crassa conidiation. Arch Biochem Biophys, 319, 519-524.
62. Trinci A P J & Righelato R C, 1970. Changes in constituents and ultrastructure of hyphal compartments during autolysis of glucose-starved Penicillium chrysogenum. J Gen Microbiol. 60, 239-249.
63. White S et al, 2002. The autolysis of industrial filamentous fungi. Crit Rev Biotechnol, 22, 1-14.
64. Zhang Y & Herman B, 2002. Ageing and apoptosis. Mech Ageing Dev, 123, 245-260.