Radioiodinated SB 207710 as a radioligand in vivo: Imaging of brain 5-HT4 receptors with SPET

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 30, Issue 11, 2003, Pages 1520-1528

  Pike, Victor W ^a,f   Halldin, Christer ^b   Nobuhara, Kenji ^b   Hiltunen, Julka ^c   Mulligan, Rachel S ^a,d   Swahn, Carl Gunnar ^b   Karlsson, Per ^b   Olsson, Hans ^b   Hume, Susan P ^a   Hirani, Ella ^a   Whalley, Jaqueline ^a   Pilowsky, Lyn S ^d,e   Larsson, Stig ^b   Schnell, Per Olof ^b   Ell, Peter J ^e   Farde, Lars ^b  

^a HAMMERSMITH HOSPITAL   (United Kingdom)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c MAP Medical Technologies Oy   (Finland)

^d KING'S COLLEGE LONDON   (United Kingdom)

^e ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^f NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

Author keywords

5 HT4 receptors; Brain; Imaging; Radioligand; Single photon emission tomography; 123I SB 207710

Indexed keywords

8 AMINO 7 IODO 1,4 BENZODIOXAN 5 CARBOXYLIC ACID 1 BUTYL 4 PIPERIDINYLMETHYL ESTER; IODINE 123; IODINE 125; NEUROTRANSMITTER RECEPTOR; RADIOLIGAND; SEROTONIN 4 ANTAGONIST; SEROTONIN 4 RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN REGION; COGNITION; CORPUS STRIATUM; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG SYNTHESIS; DRUG UPTAKE; IODODESTANNYLATION; ISOTOPE LABELING; MALE; MEMORY; MONKEY; NEUROPSYCHIATRY; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RADIOACTIVITY; RADIOIODINATION; RAT; RECEPTOR DENSITY; SEROTONINERGIC SYSTEM; SINGLE PHOTON EMISSION TOMOGRAPHY;

EID: 0242386656     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-003-1307-x     Document Type: Article

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