Autocatalytically Fragmented Light Chain of Botulinum A Neurotoxin Is Enzymatically Active

Biochemistry

Volumn 42, Issue 43, 2003, Pages 12539-12549

  Ahmed, S Ashraf ^a   McPhie, Peter ^b   Smith, Leonard A ^a  

^a UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; CATALYST ACTIVITY; PH EFFECTS; TOXIC MATERIALS;

AUTOCATALYTIC FRAGMENTATION;

PROTEINS;

BOTULINUM TOXIN A; GLYCEROL; NEUROTOXIN; PEPTIDE; PROTEINASE; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; ZINC; ZINC CHLORIDE;

ARTICLE; CATALYSIS; COMPETITIVE INHIBITION; CONCENTRATION RESPONSE; CONFORMATIONAL TRANSITION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME DEGRADATION; MOLECULAR MECHANICS; PH; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; BINDING SITES; BLOTTING, WESTERN; BOTULINUM TOXINS; CATALYSIS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HYDROGEN-ION CONCENTRATION; MOLECULAR SEQUENCE DATA;

BACTERIA (MICROORGANISMS);

EID: 0242381350     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi030062c     Document Type: Article

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