Increased Density of Human Immunodeficiency Virus Type 1 Coreceptors CCR5 and CXCR4 on the Surfaces of CD4+ T Cells and Monocytes of Patients with Schistosoma mansoni Infection

Infection and Immunity

Volumn 71, Issue 11, 2003, Pages 6668-6671

  Secor, W Evan ^a,c   Shah, Amil ^b   Mwinzi, Pauline M N ^b   Ndenga, Bryson A ^b   Watta, Caroline O ^b   Karanja, Diana M S ^b  

^a NATL CENTER FOR INFECTIOUS DISEASES   (United States)

^b KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CXCR4;

ADULT; ARTICLE; CELL INVASION; CELL SURFACE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC VALUE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN TISSUE; KENYA; MONOCYTE; NONHUMAN; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RECEPTOR DENSITY; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS; T LYMPHOCYTE ACTIVATION; WORKER;

ACQUIRED IMMUNODEFICIENCY SYNDROME; CD4-POSITIVE T-LYMPHOCYTES; HIV-1; HUMANS; RECEPTORS, CCR5; RECEPTORS, CXCR4; SCHISTOSOMIASIS MANSONI;

EID: 0242381179     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.71.11.6668-6671.2003     Document Type: Article

References (19)

1. Bentwich, Z., A. Kalinkovich, and Z. Weisman. 1995. Immune activation is a dominant factor in the pathogenesis of AIDS in Africa. Immunol. Today 16:187-191.
2. Bentwich, Z., G. Maartens, D. Torten, A. A. Lal, and R. B. Lal. 2000. Concurrent infections and HIV pathogenesis. AIDS 14:2071-2081.
3. Bleul, C. C., L. Wu, J. A. Moxie, T. A. Springer, and C. R. Mackay. 1997. The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes. Proc. Natl. Acad. Sci. USA 94:1925-1930.
4. Brewer, D. D., S. Brody, E. Drucker, D. Gisselquist, S. F. Minkin, J. J. Potterat, R. B. Rothenberg, and F. Vachon. 2003. Mounting anomalies in the epidemiology of HIV in Africa: cry the beloved paradigm. Int. J. STD AIDS 14:144-147.
5. Buvé, A., K. Bishikwabo-Nsarhaza, and G. Mutangadura. 2002. The spread and effect of HIV-1 infection in sub-Saharan Africa. Lancet 359:2011-2017.
6. Gopinath, R., M. Ostrowski, S. J. Justement, A. S. Fauci, and T. B. Nutman. 2000. Filarial infections increase susceptibility to human immunodeficiency virus infection in peripheral blood mononuclear cells in vitro. J. Infect. Dis. 182:1804-1808.
7. Kalinkovich, A., Z. Weisman, Q. Leng, G. Borrow, M. Stein, Z. Greenberg, S. Zlotnikov, S. Eitan, and Z. Bentwich. 1999. Increased CCR5 expression with decreased β-chemokine secretion in Ethiopians: relevance to AIDS in Africa. J. Hum. Virol. 2:283-289.
8. Karanja, D. M. S., D. G. Colley, B. L. Nahlen, J. H. Ouma, and W. E. Secor. 1997. Studies on schistosomiasis in western Kenya. I. Evidence for immune-facilitated excretion of schistosome eggs from patients with Schistosoma mansoni and human immunodeficiency virus co-infections. Am. J. Trop. Med. Hyg. 56:515-521.
9. Karanja, D. M. S., A. W. Hightower, D. G. Colley, P. N. M. Mwinzi, K. Galil, J. Andove, and W. E. Secor. 2002. Resistance to reinfection with Schistosoma mansoni in occupationally exposed adults and the effect of HIV-1 coinfection on susceptibility to schistosomiasis: a longitudinal study. Lancet 360:592-596.
10. Moonis, M., B. Lee, R. T. Bailer, Q. Luo, and L. J. Montaner. 2001. CCR5 and CXCR4 expression correlated with X4 and R5 HIV-1 infection yet not sustained replication in Th1 and Th2 cells. AIDS 15:1941-1949.
11. Mwinzi, P. N. M., D. M. S. Karanja, D. G. Colley, A. S. S. Orago, and W. E. Secor. 2001. Cellular immune responses of schistosomiasis patients are altered by human immunodeficiency virus-1 co-infection. J. Infect. Dis. 184:488-496.
12. Nokta, M. A., X.-D. Li, J. Nichols, M. Mallen, A. Pou, D. Asmuth, and R. B. Pollard. 2001. Chemokine/CD4 receptor density ratios correlate with HIV replication in lymph nodes and peripheral blood of HIV-infected individuals. AIDS 15:161-169.
13. Shapira-Nahor, O., A. Kalinkovich, Z. Weisman, Z. Greenberg, J. Nahmias, M. Shapiro, A. Panet, and Z. Bentwich. 1998. Increased susceptibility to HIV-1 infection of peripheral blood mononuclear cells from chronically immune-activated individuals. AIDS 12:1731-1733.
14. Sozzani, S., S. Ghezzi, G. Iannolo, W. Luini, A. Borsatti, N. Polentarutti, A. Sica, M. Locati, C. Mackay, T. N. C. Wells, P. Biwas, E. Vicenzi, G. Poli, and A. Mantovani. 1998. Interleukin 10 increases CCR5 expression and HIV infection in monocytes. J. Exp. Med. 187:439-444.
15. Tokunaga, K., M. L. Greenberg, M. A. Morse, R. I. Cumming, H. K. Lyerly, and B. R. Cullen. 2001. Molecular basis for cell tropism of CXCR4-dependent human immunodeficiency virus type 1 isolates. J. Virol. 75:6776-6785.
16. United Nations. 2002. Report on the global HIV/AIDS epidemic 2002. [Online.] http://www.unaids.org/html/pub/Global-Reports/Barcelona/ BRTableCountry EstimatesEnd2001_en_pdf.html. Joint United Nations Programme on HIV/AIDS (UNAIDS), United Nations, Geneva, Switzerland.
17. Valentin, A., W. Lu, M. Rosati, R. Schneider, J. Albert, A. Carlson, and G. N. Pavlakis. 1998. Dual effect of interleukin 4 on HIV-1 expression: implications for viral phenotypic switch and disease progression. Proc. Natl. Acad. Sci. USA 95:8886-8891.
18. Wang, J., K. Crawford, M. Yuan, H. Wang, P. R. Gorry, and D. Gabuzda. 2002. Regulation of CC chemokine receptor 5 and CD4 expression and human immunodeficiency virus type 1 replication in human macrophage and microglia by T helper type 2 cytokines. J. Exp. Med. 185:885-897.
19. Weiss, H. A., M. A. Quigley, and R. J. Harris. 2000. Male circumcision and risk of HIV infection in sub-Saharan Africa: a systematic review and meta-analysis. AIDS 14:2361-2370.