메뉴 건너뛰기




Volumn 110, Issue 4, 2003, Pages 221-226

The influence of direct and antithrombin-dependent thrombin inhibitors on the procoagulant and anticoagulant effects of thrombin

Author keywords

Activated protein C; Endothelial cell; Fibrinopeptide A; Hirudin thrombin inhibitor; Melagatran

Indexed keywords

ACTIVATED PROTEIN C; ANTICOAGULANT AGENT; ANTITHROMBIN; DALTEPARIN; FIBRINOGEN; FIBRINOPEPTIDE A; HEPARIN; HIRUDIN; HIRUGEN; INOGATRAN; LOW MOLECULAR WEIGHT HEPARIN; MELAGATRAN; THROMBIN; THROMBIN INHIBITOR; THROMBOMODULIN;

EID: 0242380341     PISSN: 00493848     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0049-3848(03)00344-X     Document Type: Article
Times cited : (4)

References (29)
  • 1
    • 0029059269 scopus 로고
    • Randomized comparison of subcutaneous heparin, intravenous heparin, and aspirin in unstable angina
    • Neri Serneri G.F., Modesti A., Gensini F., Branzi A., Melandri G., Poggesi L.et al. Randomized comparison of subcutaneous heparin, intravenous heparin, and aspirin in unstable angina. Lancet. 345:1995;1201-1204.
    • (1995) Lancet , vol.345 , pp. 1201-1204
    • Neri Serneri, G.F.1    Modesti, A.2    Gensini, F.3    Branzi, A.4    Melandri, G.5    Poggesi, L.6
  • 2
    • 0027525087 scopus 로고
    • Aspirin versus heparin to prevent myocardial infarction during the acute phase of unstable angina
    • Théroux P., Waters D., Qui S., McCans J., de Guise P., Juneau M. Aspirin versus heparin to prevent myocardial infarction during the acute phase of unstable angina. Circulation. 88:1993;2045-2048.
    • (1993) Circulation , vol.88 , pp. 2045-2048
    • Théroux, P.1    Waters, D.2    Qui, S.3    McCans, J.4    De Guise, P.5    Juneau, M.6
  • 3
    • 0000189825 scopus 로고    scopus 로고
    • Low-molecular-weight heparin during instability in coronary artery disease, Fragmin during Instability in Coronary Artery Disease (FRISC) study group
    • FRISC Low-molecular-weight heparin during instability in coronary artery disease, Fragmin during Instability in Coronary Artery Disease (FRISC) study group. Lancet. 347(9001):1996;561-568.
    • (1996) Lancet , vol.347 , Issue.9001 , pp. 561-568
  • 4
    • 0032504937 scopus 로고    scopus 로고
    • Low-molecular-weight heparins in non-ST-segment elevation ischemia: The ESSENCE trial. Efficacy and safety of subcutaneous enoxaparin versus intravenous unfractionated heparin, in non-Q-wave coronary events
    • Cohen M., Demers C., Gurfinkel E.P., Turpie A.G., Fromell G.J., Goodman S.et al. Low-molecular-weight heparins in non-ST-segment elevation ischemia: the ESSENCE trial. Efficacy and safety of subcutaneous enoxaparin versus intravenous unfractionated heparin, in non-Q-wave coronary events. Am. J. Cardiol. 82(5B):1998;19L-24L.
    • (1998) Am. J. Cardiol. , vol.82 , Issue.5 B
    • Cohen, M.1    Demers, C.2    Gurfinkel, E.P.3    Turpie, A.G.4    Fromell, G.J.5    Goodman, S.6
  • 5
    • 0031951814 scopus 로고    scopus 로고
    • BCH-2763, a novel potent parenteral thrombin inhibitor, is an effective antithrombotic agent in rodent models of arterial and venous thrombosis - Comparisons with heparin, r-hirudin, hirulog, inogatran and argatroban
    • Finkle C.D., St. Pierre A., Leblond L., Deschenes I., DiMaio J., Winocour P.D. BCH-2763, a novel potent parenteral thrombin inhibitor, is an effective antithrombotic agent in rodent models of arterial and venous thrombosis - comparisons with heparin, r-hirudin, hirulog, inogatran and argatroban. Thromb. Haemost. 79(2):1998;431-438.
    • (1998) Thromb. Haemost. , vol.79 , Issue.2 , pp. 431-438
    • Finkle, C.D.1    St. Pierre, A.2    Leblond, L.3    Deschenes, I.4    DiMaio, J.5    Winocour, P.D.6
  • 6
    • 0028558549 scopus 로고
    • Inhibition of clot-bound and free (fluid-phase thrombin) by a novel synthetic thrombin inhibitor (Ro 46-6240), recombinant hirudin and heparin in human plasma
    • Gast A., Tschopp T.B., Schmid G., Hilpert K., Ackermann J. Inhibition of clot-bound and free (fluid-phase thrombin) by a novel synthetic thrombin inhibitor (Ro 46-6240), recombinant hirudin and heparin in human plasma. Blood Coagul. Fibrinolysis. 5(6):1994;879-887.
    • (1994) Blood Coagul. Fibrinolysis , vol.5 , Issue.6 , pp. 879-887
    • Gast, A.1    Tschopp, T.B.2    Schmid, G.3    Hilpert, K.4    Ackermann, J.5
  • 7
    • 0025146426 scopus 로고
    • Clot bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III independent inhibitors
    • Weitz J., Hudoda M., Masel D., Maraganore J., Hirsch J. Clot bound thrombin is protected from inhibition by heparin-antithrombin III but is susceptible to inactivation by antithrombin III independent inhibitors. J. Clin. Invest. 86:1990;385-391.
    • (1990) J. Clin. Invest. , vol.86 , pp. 385-391
    • Weitz, J.1    Hudoda, M.2    Masel, D.3    Maraganore, J.4    Hirsch, J.5
  • 8
    • 0033528281 scopus 로고    scopus 로고
    • Effects of recombinant hirudin (lepirudin) compared with heparin on death, myocardial infarction, refractory angina, and revascularisation procedures in patients with acute myocardial ischaemia without ST elevation: A randomised trial. Organisation to Assess Strategies for Ischemic Syndromes (OASIS-2) investigators
    • OASIS-2 Effects of recombinant hirudin (lepirudin) compared with heparin on death, myocardial infarction, refractory angina, and revascularisation procedures in patients with acute myocardial ischaemia without ST elevation: a randomised trial. Organisation to Assess Strategies for Ischemic Syndromes (OASIS-2) investigators. Lancet. 353(9151):1999;429-438.
    • (1999) Lancet , vol.353 , Issue.9151 , pp. 429-438
  • 9
    • 0029835392 scopus 로고    scopus 로고
    • A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes
    • The GUSTO IIb investigators A comparison of recombinant hirudin with heparin for the treatment of acute coronary syndromes. N. Engl. J. Med. 335:1996;775-782.
    • (1996) N. Engl. J. Med. , vol.335 , pp. 775-782
  • 10
    • 0030762734 scopus 로고    scopus 로고
    • A low molecular weight, selective thrombin inhibitor, inogatran, vs. heparin, for unstable coronary artery disease in 1209 patients
    • The Thrombin Inhibition In Myocardial Ischemia (TRIM) Study Group A low molecular weight, selective thrombin inhibitor, inogatran, vs. heparin, for unstable coronary artery disease in 1209 patients. Eur. Heart J. 18:1997;1416-1425.
    • (1997) Eur. Heart J. , vol.18 , pp. 1416-1425
  • 11
    • 0033179314 scopus 로고    scopus 로고
    • Anticoagulant properties, clinical efficacy and safety of efegatran, a direct thrombin inhibitor, in patients with unstable angina
    • Klootwijk P., Lenderink T., Meij S., Boersma H., Melkert R., Umans V.A. et al. Anticoagulant properties, clinical efficacy and safety of efegatran, a direct thrombin inhibitor, in patients with unstable angina. Eur. Heart J. 20(15):1999;1101-1111.
    • (1999) Eur. Heart J. , vol.20 , Issue.15 , pp. 1101-1111
    • Klootwijk, P.1    Lenderink, T.2    Meij, S.3    Boersma, H.4    Melkert, R.5    Umans, V.A.6
  • 12
    • 0345621622 scopus 로고    scopus 로고
    • Thrombin inhibitors suppress the thrombin-thrombomodulin-mediated generation of activated protein C
    • Linder R., Blomback M., Egberg N., Grip L. Thrombin inhibitors suppress the thrombin-thrombomodulin-mediated generation of activated protein C. Thromb. Res. 95(2):1999;117-125.
    • (1999) Thromb. Res. , vol.95 , Issue.2 , pp. 117-125
    • Linder, R.1    Blomback, M.2    Egberg, N.3    Grip, L.4
  • 13
    • 0035894619 scopus 로고    scopus 로고
    • Effect of different types of thrombin inhibitors on thrombin/ thrombomodulin modulated activation of protein C in vitro
    • Mattsson C., Menschik-Lundin A., Nylander S., Gyzander E., Deinum J. Effect of different types of thrombin inhibitors on thrombin/thrombomodulin modulated activation of protein C in vitro. Thromb. Res. 104(6):2001;475-486.
    • (2001) Thromb. Res. , vol.104 , Issue.6 , pp. 475-486
    • Mattsson, C.1    Menschik-Lundin, A.2    Nylander, S.3    Gyzander, E.4    Deinum, J.5
  • 14
    • 0037296305 scopus 로고    scopus 로고
    • Inhibition of endothelial cell mediated generation of activated protein C by direct and antithrombin dependent thrombin inhibitors
    • Linder R., Frebelius S., Jansson K., Swedenborg J. Inhibition of endothelial cell mediated generation of activated protein C by direct and antithrombin dependent thrombin inhibitors. Blood Coagul. Fibrinolysis. 14:2003;139-146.
    • (2003) Blood Coagul. Fibrinolysis , vol.14 , pp. 139-146
    • Linder, R.1    Frebelius, S.2    Jansson, K.3    Swedenborg, J.4
  • 15
    • 0026707875 scopus 로고
    • Serial cultivation of adult human endothelium from the great saphenous vein
    • Haegerstrand A., Gillis C., Bengtsson L. Serial cultivation of adult human endothelium from the great saphenous vein. J. Vasc. Surg. 16:1992;280-285.
    • (1992) J. Vasc. Surg. , vol.16 , pp. 280-285
    • Haegerstrand, A.1    Gillis, C.2    Bengtsson, L.3
  • 17
    • 0019124677 scopus 로고
    • A solid phase immuno enzymological assay for the measurement of human fibrinopeptide A
    • Soria J., Soria C., Ryckewaert J.J. A solid phase immuno enzymological assay for the measurement of human fibrinopeptide A. Thromb. Res. 20(4):1980;425-435.
    • (1980) Thromb. Res. , vol.20 , Issue.4 , pp. 425-435
    • Soria, J.1    Soria, C.2    Ryckewaert, J.J.3
  • 19
    • 0026781041 scopus 로고
    • The fifth and sixth growth factor-like domains of thrombomodulin bind to the anion-binding exosite of thrombin and alter its specificity
    • Ye J., Liu L.W., Esmon C.T., Johnson A.E. The fifth and sixth growth factor-like domains of thrombomodulin bind to the anion-binding exosite of thrombin and alter its specificity. J. Biol. Chem. 267(16):1992;11023-11028.
    • (1992) J. Biol. Chem. , vol.267 , Issue.16 , pp. 11023-11028
    • Ye, J.1    Liu, L.W.2    Esmon, C.T.3    Johnson, A.E.4
  • 20
    • 0037296305 scopus 로고    scopus 로고
    • Inhibition of endothelial cell-mediated generation of activated protein C by direct and antithrombin-dependent thrombin inhibitors
    • Linder R., Frebelius S., Jansson K., Swedenborg J. Inhibition of endothelial cell-mediated generation of activated protein C by direct and antithrombin-dependent thrombin inhibitors. Blood Coagul. Fibrinolysis. 14(2):2003;139-146.
    • (2003) Blood Coagul. Fibrinolysis , vol.14 , Issue.2 , pp. 139-146
    • Linder, R.1    Frebelius, S.2    Jansson, K.3    Swedenborg, J.4
  • 21
    • 0030586448 scopus 로고    scopus 로고
    • Reduced response to activated protein C is associated with increased risk for cerebrovascular disease
    • van der Bom J.G., Bots M.L., Haverkate F., Slagboom P.E., Meijer P., de Jong P.T.et al. Reduced response to activated protein C is associated with increased risk for cerebrovascular disease. Ann. Intern. Med. 125(4):1996;265-269.
    • (1996) Ann. Intern. Med. , vol.125 , Issue.4 , pp. 265-269
    • Van Der Bom, J.G.1    Bots, M.L.2    Haverkate, F.3    Slagboom, P.E.4    Meijer, P.5    De Jong, P.T.6
  • 22
    • 0019789514 scopus 로고
    • Deficency of protein C in congenital thrombotic disease
    • Griffin J.H., Evatt B., Zimmerman T.S. Deficency of protein C in congenital thrombotic disease. J. Clin. Invest. 68:1981;1370-1373.
    • (1981) J. Clin. Invest. , vol.68 , pp. 1370-1373
    • Griffin, J.H.1    Evatt, B.2    Zimmerman, T.S.3
  • 23
    • 14444281536 scopus 로고    scopus 로고
    • Prevalence of factor V Leiden (APCR) and other inherited thrombophilias in young patients with myocardial infarction and normal coronary arteries
    • Dacosta A., Tardy-Poncet B., Isaaz K., Cerisier A., Mismetti P., Simitsidis S.et al. Prevalence of factor V Leiden (APCR) and other inherited thrombophilias in young patients with myocardial infarction and normal coronary arteries. Heart. 80(4):1998;338-340.
    • (1998) Heart , vol.80 , Issue.4 , pp. 338-340
    • Dacosta, A.1    Tardy-Poncet, B.2    Isaaz, K.3    Cerisier, A.4    Mismetti, P.5    Simitsidis, S.6
  • 25
    • 0033143554 scopus 로고    scopus 로고
    • Factor V Q506 (resistance to activated protein C) and prognosis after acute coronary syndrome
    • Holm J., Hillarp A., Zoller B., Erhardt L., Berntorp E., Dahlback B. Factor V Q506 (resistance to activated protein C) and prognosis after acute coronary syndrome. Thromb. Haemost. 81(6):1999;857-860.
    • (1999) Thromb. Haemost. , vol.81 , Issue.6 , pp. 857-860
    • Holm, J.1    Hillarp, A.2    Zoller, B.3    Erhardt, L.4    Berntorp, E.5    Dahlback, B.6
  • 26
    • 0034050916 scopus 로고    scopus 로고
    • Prevalence of factor V Leiden in patients with myocardial infarction and normal coronary angiography
    • Mansourati J., Da Costa A., Munier S., Mercier B., Tardy B., Ferec C.et al. Prevalence of factor V Leiden in patients with myocardial infarction and normal coronary angiography. Thromb. Haemost. 83(6):2000;822-825.
    • (2000) Thromb. Haemost. , vol.83 , Issue.6 , pp. 822-825
    • Mansourati, J.1    Da Costa, A.2    Munier, S.3    Mercier, B.4    Tardy, B.5    Ferec, C.6
  • 27
    • 0030984288 scopus 로고    scopus 로고
    • Factor V Leiden (resistance to activated protein C) increases the risk of myocardial infarction in young women
    • Rosendaal F.R., Siscovick D.S., Schwartz S.M., Beverly R.K., Psaty B.M., Longstreth W.T. Jr.et al. Factor V Leiden (resistance to activated protein C) increases the risk of myocardial infarction in young women. Blood. 89(8):1997;2817-2821.
    • (1997) Blood , vol.89 , Issue.8 , pp. 2817-2821
    • Rosendaal, F.R.1    Siscovick, D.S.2    Schwartz, S.M.3    Beverly, R.K.4    Psaty, B.M.5    Longstreth W.T., Jr.6
  • 28
    • 0033968221 scopus 로고    scopus 로고
    • G-33A mutation in the promoter region of thrombomodulin gene and its association with coronary artery disease and plasma soluble thrombomodulin levels
    • Li Y.H., Chen J.H., Wu H.L., Shi G.Y., Huang H.C., Chao T.H.et al. G-33A mutation in the promoter region of thrombomodulin gene and its association with coronary artery disease and plasma soluble thrombomodulin levels. Am. J. Cardiol. 85(1):2000;8-12.
    • (2000) Am. J. Cardiol. , vol.85 , Issue.1 , pp. 8-12
    • Li, Y.H.1    Chen, J.H.2    Wu, H.L.3    Shi, G.Y.4    Huang, H.C.5    Chao, T.H.6
  • 29
    • 0035853133 scopus 로고    scopus 로고
    • Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease
    • Wu K.K., Aleksic N., Ahn C., Boerwinkle E., Folsom A.R., Juneja H. Thrombomodulin Ala455Val polymorphism and risk of coronary heart disease. Circulation. 103(10):2001;1386-1389.
    • (2001) Circulation , vol.103 , Issue.10 , pp. 1386-1389
    • Wu, K.K.1    Aleksic, N.2    Ahn, C.3    Boerwinkle, E.4    Folsom, A.R.5    Juneja, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.