Synthesis of niruriside a HIV REV/RRE binding inhibitor

Recueil des Travaux Chimiques des Pays-Bas-Journal of the Royal Netherlands

Volumn 115, Issue 6, 1996, Pages 339-340

  Duynstee, H I ^a   Ovaa, H ^a   Van Der Marel, G A ^a   Van Boom, J H ^a  

^a LEIDEN UNIVERSITY   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0242370686     PISSN: 01650513     EISSN: None     Source Type: Journal    
DOI: 10.1002/recl.19961150607     Document Type: Article

References (8)

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6. 3).
7. Short treatment (i.e. 30 min) of 4 with 60% acetic acid at 50°C resulted in the selective cleavage of the 4,6-isopropylidene group. Unfortunately, prolonged acid hydrolysis of the resulting mono-isopropylidene derivative was accompanied by concomitant removal of one of the TBDMS groups.
8. J.T. Randolph, S.J. Danishefsky, J. Am. Chem. Soc. 117, 5693 (1995).