Chitosan for weight loss and cholesterol management

American Journal of Health-System Pharmacy

Volumn 60, Issue 13, 2003, Pages

  Shields, Kelly M ^a   Smock, Nick ^b   McQueen, Cydney E ^a   Bryant, Patrick J ^a  

^a UNIVERSITY OF MISSOURI KANSAS CITY   (United States)

^b True Care Pharmacies   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHITOSAN; CHOLESTEROL; DEXFENFLURAMINE; EPHEDRA EXTRACT; PHENTERMINE; SIBUTRAMINE; TETRAHYDROLIPSTATIN; ANOREXIGENIC AGENT; CHITIN; DRUG DERIVATIVE; HYPOCHOLESTEROLEMIC AGENT;

ALTERNATIVE MEDICINE; CENTRAL NERVOUS SYSTEM DISEASE; CLINICAL TRIAL; DIET SUPPLEMENTATION; DIET THERAPY; DRUG BINDING; DRUG DELIVERY SYSTEM; DRUG SAFETY; EDITORIAL; GASTROINTESTINAL SYMPTOM; HUMAN; NONHUMAN; OBESITY; PERIODONTITIS; PRIORITY JOURNAL; TABLET FORMULATION; VALVULAR HEART DISEASE; WEIGHT CONTROL; WEIGHT REDUCTION; DRUG EFFECT; HYPERCHOLESTEROLEMIA; REVIEW;

ANTICHOLESTEREMIC AGENTS; APPETITE DEPRESSANTS; CHITIN; CHITOSAN; CLINICAL TRIALS; HUMANS; HYPERCHOLESTEROLEMIA; WEIGHT LOSS;

EID: 0242368083     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajhp/60.13.1310     Document Type: Editorial

References (21)

1. Flegal KM, Carroll MD, Kuczmarski RJ et al. Overweight and obesity in the United States: prevalence and trends, 1960-1994. Int J Obes. 1998; 22:39-47.
2. Troiano RP, Flegal KM. Overweight children and adolescents: description, epidemiology, and demographics. Pediatrics. 1998; 101(3, suppl):497-504.
3. Jellin J, ed. The natural medicine comprehensive database. Stockton, CA: Therapeutic Research; 2002.
4. DerMarderosian A, Beutler JA, eds. Facts and comparisons: the review of natural products. St. Louis: Wolters Kluwer; 2002.
5. Gennaro AR, ed. Remington: the science and practice of pharmacy. 20th ed. Philadelphia: Lippincott Williams & Wilkins; 2000.
6. Nauss JL, Thomson JL, Nagyuvary Y et al. The binding of micellar lipids to chitosan. Lipids. 1983; 18:246-7.
7. Fetrow CW, Avila JR, eds. Professional's handbook of complementary and alternative medicines. Springhouse, PA: Springhouse; 2001.
8. Hendler SS, Rorvik D, eds. PDR for nutritional supplements. Montvale, NJ: Medical Economics; 2001.
9. Muzzarelli RA. Clinical and biochemical evaluation of chitosan for hypercholesterolemia and overweight control. In: Jolles P, Muzzarelli RA, eds. Chitin and chitinases. Basel, Switzerland: Birkhäuser; 1999:293-304.
10. Pittler MH, Abbot NC, Harkness EF et al. Randomized, double-blind trial of chitosan for body weight reduction. Eur J Clin Nutr. 1999; 53:379-81.
11. Schiller RN, Barrager E, Schauss AG et al. A randomized, double-blind, placebo-controlled study examining the effects of a rapidly soluble chitosan dietary supplement on weight loss and body composition in overweight and mildly obese individuals. J Am Nutraceut Assoc. 2001; 4:42-9.
12. Gades MD, Stern JS. Chitosan supplementation does not affect fat absorption in healthy males fed a high-fat diet, a pilot study. Int J Obes. 2002; 26:119-22.
13. Guerciolini R, Radu-Radulescu L, Boldrin R et al. Comparative evaluation of fecal fat excretion induced by orlistat and chitosan. Obes Res. 2001; 9:364-7.
14. Giustina A, Ventura P. Weight-reducing regimens in obese subjects: effects of a new dietary fiber integrator. Acta Toxicol Ther. 1995; 16:199-214.
15. Wuolijoki E, Hirvela T, Ylitalo P. Decrease in serum LDL cholesterol with microcrystalline chitosan. Methods Find Exp Clin Pharmacol. 1999; 21:357-61.
16. Maezaki Y, Tsuji K, Nakagawa Y et al. Hypocholesterolemic effect of chitosan in adult males. Biosci Biotech Biochem. 1993; 57:1439-44.
17. Ho SC, Tai ES, Eng PHK et al. In the absence of dietary surveillance, chitosan does not reduce plasma lipids or obesity in hypercholesterolaemic obese Asian subjects. Singapore Med J. 2001; 42:6-10.
18. Sciutto AM, Colombo P. Lipid-lowering effect of chitosan dietary integrator and hypocaloric diet in obese subjects. Acta Toxicol Ther. 1995; 16:215-30.
19. Veneroni G, Veneroni F, Contos S et al. Effect of a new chitosan dietary integrator and hypocaloric diet on hyperlipidemia and overweight in obese patients. Acta Toxicol Ther. 1996; 16:53-70.
20. Colombo P, Sciutto AM. Nutritional aspects of chitosan employment in hypocaloric diet. Acta Toxicol Ther. 1996; 16:287-302.
21. Macchi G. A new approach to the treatment of obesity: chitosan's effect on body weight reduction and plasma cholesterol levels. Acta Toxicol Ther. 1996; 16:303-20.