Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care
Angus DC, Linde-Awirble WT, Lidicker J et al. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001; 29:1303-10.
Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis
Bone RC, Balk RA, Cerra FB et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest. 1992; 101:1644-55.
Recombinant human activated protein C, drotrecogin alfa activated: A novel therapy for severe sepsis
Kanji S, Devlin JW, Piekos KA et al. Recombinant human activated protein C, drotrecogin alfa activated: a novel therapy for severe sepsis. Pharmacotherapy. 2001; 21:1389-402.
Recombinant human activated protein C: A system modulator of vascular function for treatment of severe sepsis
Grinnell BW, Joyce D. Recombinant human activated protein C: a system modulator of vascular function for treatment of severe sepsis. Crit Care Med. 2001; 29(suppl):S53-61.
Efficacy and safety of recombinant human activated protein C for severe sepsis (PROWESS trial)
Bernard GR, Vincent JL, Laterre PF et al. Efficacy and safety of recombinant human activated protein C for severe sepsis (PROWESS trial). N Engl J Med. 2001; 344:699-709.
Sounding board: Risks and benefits of activated protein C in the treatment for severe sepsis
Warren HS, Suffredini AF, Eichacker PQ et al. Sounding board: risks and benefits of activated protein C in the treatment for severe sepsis. N Engl J Med. 2002; 347:1027-30.