The cerebral microcirculation in ischemia and hypoxemia

Advances in Experimental Medicine and Biology

Volumn 530, Issue , 2003, Pages 347-357

  Hudetz, Antal G ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOREGULATION; BLOOD FLOW VELOCITY; BRAIN BLOOD FLOW; BRAIN CAPILLARY; BRAIN CIRCULATION; BRAIN HYPOXIA; BRAIN ISCHEMIA; CONFERENCE PAPER; ERYTHROCYTE MEMBRANE; HEMATOCRIT; HEMORRHAGIC SHOCK; HYPOXEMIA; MICROCIRCULATION; PRIORITY JOURNAL; REPERFUSION; SYMPATHETIC TONE; TISSUE INJURY;

EID: 0242362067     PISSN: 00652598     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-4615-0075-9_32     Document Type: Conference Paper

References (34)

1. Ames A, Wright RL, Kowada M, Thurston JM and Majno G. Cerebral ischemia II. The no-reflow phenomenon. Am J Pathol 1968;52:437-453.
2. Bauer R, Iijima T and Hossmann KA Influence of severe hemodilution on brain function and brain oxidative metabolism in the cat. Intensive Care Med 1996;22:47-51.
3. Biswal B, Hudetz AG, Yetkin FZ, Haughton VM, Hyde JS. Hypercapnia reversibly suppresses low-frequency fluctuations in the human motor cortex during rest using echoplanar MRI. J Cereb Blood Flow Metab 1997;17:301-308.
4. Cuevas P, Gutierrez-Diaz JA, Reimers D, Dujovny M, Diaz FG and Ausman JI. Pericyte endothelial gap junctions in human cerebral capillaries. Anat Embryol (Berlin) 1984;170:155-159.
5. del Zoppo GJ. Microvascular changes during cerebral ischemia and reperfusion. Cerebrovasc Brain Metab Rev 1994; 6:47-96.
6. Dirnagl U, Niwa K, Sixt G and Villringer A. Cortical hypoperfusion after global forebrain ischemia in rats is not caused by microvascular leukocyte plugging. Stroke 1994; 25:1028-1038.
7. Dodge AB, Hechtman HB and Shepro D. Microvascular endothelial-derived autacoids regulate pericyte contractility. Cell Motil Cytoskeleton 1991;18:180-188.
8. Dóra E., Kovách AG. Effect of acute arterial hypo-and hypertension on cerebrocortical NAD/NADH redox state and vascular volume. J Cereb Blood Flow Metabol 1982;2:209-219.
9. Dóra E., and Kovách AG. Metabolic and vascular volume oscillations in the cat brain cortex. Acta Physiol. Acad. Sci Hung 1981; 57:261-75.
10. Dóra E., Urbanics R. Effect of surplus amount of oxygen on the cerebrocortical microcirculatory reactions associated to moderate arterial hypotension. Acta Physiol Hung 1986; 67:213-21.
11. Dóra E Effect of topically administered epinephrine, norepinephrine and acetylcholine on cerebralcortical vascular volume and NAD/NADH redox state. In: The Cerebral Veins (Auer LM and Loew F. Eds) Springer-Verlag Wien. New York. 1983;pp 193-199.
12. Ennis SR, Keep RF, Schielke GP and Betz AL. Decrease in perfusion of cerebral capillaries during incomplete ischemia and reperfusion. J Cereb Blood Flow Metab 1990;10:213-220.
13. Garcia JH, Liu KF, Yoshida Y, Lian J, Chen S and del Zoppo GJ. Influx of leukocytes and platelets in an evolving brain infarct (Wistar rat). Am J Pathol 1994; 144:188-199.
14. Gjedde A, Kuwabara H and Hakim AM. Reduction of functional capillary density in human brain after stroke. J Cereb Blood Flow Metab 1990;10:317-326.
15. Haefliger IO, Zschauer A and Anderson DA. Relaxation of retinal pericyte contractile tone through the nitric-oxide-cyclic guanosine monophosphate pathway. Invest Opthalamol Vis Sci 1994;35:991-997.
16. Harder DR, Narayanan J, Gebremedhin D and Roman RJ Transduction of physical force by the vascular wall. Trends Cardiovasc Med 1995; 5:7-14.
17. Hudetz AG Blood flow in the cerebral capillary network: A review emphasizing observations with intravital microscopy. Microcirculation 1997;4:233-252.
18. Hudetz AG, Fehér G and Kampine JP. Heterogeneous autoregulation of cerebrocortical capillary flow: Evidence for functional thoroughfare channels? Microvasc Res 1996; 51:131-136.
19. Hudetz AG, Fehér G, Knuese DE and Kampine JP. Erythrocyte flow heterogeneity in the cerebrocortical capillary network. Adv Exp Med Biol 1994; 345:633-642.
20. Hudetz AG, Fehér G, Weigle CGM, Knuese DE and Kampine JP. Video microscopy of cerebrocortical capillary flow: response to hypotension and intracranial hypertension. Am J Physiol 1995; 268:H2202-H2210.
21. Hudetz AG, Roman RJ and Harder DR. Spontaneous flow oscillations in the cerebral cortex during acute changes in mean arterial pressure. J Cereb Blood Flow Metab 1992;12:491-499.
22. Hudetz AG, Shen H and Kampine, JP. Nitric oxide from neuronal NOS plays critical role in cerebral capillary flow response to hypoxia. Am J Physiol 1998; 274:H982-989.
23. Hudetz AG, Wood JD, Biswal BB, Krolo I and Kampine JP Effect of hemodilution on RBC velocity, supply rate and hematocrit in the cerebral capillary network. J Appl Physiol 1999; 87:505-509.
24. Hudetz AG, Wood JD and Kampine JP (1999) Nitric oxide synthase inhibitor augments post-ischemic leukocyte adhesion in the cerebral microcirculation in vivo. Neurol. Res. 21:378-384.
25. Kelley C, D'Amore P, Hechtman HB and Shepro D. Vasoactive hormones and cAMP affect pericyte contraction and stress fibres in vitro. Journal of Muscle Research Cell Motil 1988; 9:184-194.
26. Kovách, A.G. Cerebral circulation in hypoxia and ischemia. Progr Clin Biol Res 1988; 264:147-158.
27. Kovach AG, Dora E, Hamar J, Eke A and Szabo L Transient metabolic and vascular volume changes following rapid blood pressure alterations which precede the autoregulatory vasodilation of cerebral cortical vessels. Adv Exp Med Biol 1977;94:705-711.
28. Motti ED, Imhof HG and Yasargil MG. The terminal vascular bed in the superficial cortex of the rat. An SEM study of corrosion casts. J Neurosurg 1986; 65:834-846.
29. Nakai K, Imai H, Kamel I, Itakura T, Komari N, Kimura H, Nagai T and Meada T. Microangioarchitecture of rat parietal cortex with special reference to vascular sphincters. Stroke 1981;12:653-659.
30. Nehls V and Drenckhahn D. The versatility of microvascular pericytes: From mesenchyme to smooth muscle? Histochemistry 1993; 99:1-12.
31. Pfeifer RA. (1928) In: Die Angioarchitectonik der Grosshirnrinde Eds.) Springer. Berlin.
32. Wei EP and Kontos HA Responses of pial arterioles to increased venous pressure. J Cereb Blood Flow Metab 1981;1:S329.
33. Woolsey TA, Rovainen CM, Cox SB, Henegar MH, Liang GE, Liu D, Moskalenko YE, Sui J and Wei L. Neuronal units linked to microvascular modules in cerebral cortex: response elements for imaging the brain. Cereb Cortex 1996;6:647-660.
34. Yamakawa T, Yamaguchi S, Niimi H and Sugiyama I. White blood cell plugging and blood flow maldistribution in the capillary network of cat cerebral cortex in acute hemorrhagic hypotension: An intravital microscopic study. Circ Shock 1987;22:323-332.