A Randomized Study of Prophylactic Catheter Ablation in Asymptomatic Patients with the Wolff-Parkinson-White Syndrome

New England Journal of Medicine

Volumn 349, Issue 19, 2003, Pages 1803-1811

  Pappone, Carlo ^a   Santinelli, Vincenzo ^b   Manguso, Francesco ^b   Augello, Giuseppe ^a   Santinelli, Ornelia ^b   Vicedomini, Gabriele ^a   Gulletta, Simone ^a   Mazzone, Patrizio ^a   Tortoriello, Valter ^a   Pappone, Alessia ^a   Dicandia, Cosimo ^a   Rosanio, Salvatore ^c  

^a SAN RAFFAELE HOSPITAL   (Italy)

^b FEDERICO II UNIVERSITY HOSPITAL   (Italy)

^c University of Texas Medical Branch School of Medicine   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CARDIOVASCULAR RISK; CATHETER ABLATION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ELECTROPHYSIOLOGY; FEMALE; HEART ARRHYTHMIA; HIGH RISK PATIENT; HUMAN; KAPLAN MEIER METHOD; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROPHYLAXIS; RANDOMIZED CONTROLLED TRIAL; WOLFF PARKINSON WHITE SYNDROME; ELECTROCARDIOGRAPHY; HEART FUNCTION TEST; MIDDLE AGED; PATHOPHYSIOLOGY; RISK ASSESSMENT; SURVIVAL;

ADOLESCENT; ADULT; CATHETER ABLATION; ELECTROCARDIOGRAPHY; ELECTROPHYSIOLOGIC TECHNIQUES, CARDIAC; FEMALE; HUMANS; MALE; MIDDLE AGED; RISK ASSESSMENT; SURVIVAL ANALYSIS; WOLFF-PARKINSON-WHITE SYNDROME;

EID: 0242348705     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJMoa035345     Document Type: Article

References (19)

1. LeLorier P, Klein GJ, Krahn A, Yee R, Skanes A. Should patients with assymptomatic Wolff-Parkinson-White pattern undergo a catheter ablation? Curr Cardiol Pep 2001;3:301-4.
2. Pappone C, Santinelli V, Rosanio S, et al. Usefulness of invasive electrophysiologic testing to stratify the risk of arrhythmic events in asymptomatic patients with Wolff-Parkinson-White pattern: results from a large prospective long-term follow-up study. J Am Coll Cardiol 2003;41:239-44.
3. Zardini M, Leitch JW, Guiraudon GM, Klein GJ, Yee R. Atrioventricular nodal re-entry and dual atrioventricular node physiology in patients undergoing accessory pathway ablation. Am J Cardiol 1990;66:1388-9.
4. Csanadi Z, Klein GJ, Yee R, Thakur RK, Li H. Effect of dual atrioventricular node pathways on atrioventricular reentrant tachycardia. Circulation 1995;91:2614-8.
5. Leitch JW, Klein GJ, Yee R, Murdock C. Prognostic value of electrophysiology testing in asymptomatic patients with Wolff-Parkinson-White pattern. Circulation 1990;82:1718-23. [Erratum, Circulation 1991;83:1124.]
6. Leitch JW, Klein GJ, Yee R, Murdock C. Prognostic value of electrophysiology testing in asymptomatic patients with Wolff-Parkinson-White pattern. Circulation 1990;82:1718-23. [Erratum, Circulation 1991;83:1124.]
7. Berkman NL, Lamb LE. The Wolff-Parkinson-White electrocardiogram: a follow-up study of five to twenty-eight years. N Engl J Med 1968;278:492-4.
8. Munger TM, Parker DL, Hammill SC, et al. A population study of the natural history of Wolff-Parkinson-White syndrome in Olmsted County, Minnesota, 1953 to 1989. Circulation 1993;87:866-73.
9. Fitzsimmons PJ, McWhirter PD, Peterson DW, Kruyer WB. The natural history of Wolff-Parkinson-White syndrome in 228 military aviators: a long-term follow-up of 22 years. Am Heart J 2001;142:530-6.
10. Klein GJ, Bashore TM, Sellers TD, Pritchett ELC, Smith WM, Gallagher JJ. Ventricular fibrillation in the Wolff-Parkinson-White syndrome. N Engl J Med 1979;301:1080-5.
11. Montoya PT, Brugada P, Smeets J, et al. Ventricular fibrillation in the Wolff-Parkinson-White syndrome. Eur Heart J 1991;12:144-50.
12. Timmermans C, Smeets JL, Rodriguez LM, Vrouchos G, van den Dool A, Wellens HJ. Aborted sudden death in the Wolff-Parkinson-White syndrome. Am J Cardiol 1995;76:492-4.
13. Teo WS, Klein GJ, Guiraudon GM, et al. Multiple accessory pathways in the Wolff-Parkinson-White syndrome as a risk factor for ventricular fibrillation. Am J Cardiol 1991;67:889-91.
14. Klein GJ, Yee K, Sharma AD. Longitudinal electrophysiologic assessment of asymptomatic patients with the Wolff-Parkinson-White electrocardiographic pattern. N Engl J Med 1989;320:1229-33.
15. Satoh M. Aizawa Y, Funazaki T, et al. Electrophysiologic evaluation of asymptomatic patients with the Wolff-Parkinson-White pattern. Pacing Clin Electrophysiol 1989;12:413-20.
16. Beckman KJ, Gallastegui JL, Bauman JL, Hariman RJ. The predictive value of electrophysiologic studies in untreated patients with the Wolff-Parkinson-White syndrome. J Am Coll Cardiol 1990;15:640-7.
17. Brembilla-Perrot B, Ghawi R. Electrophysiological characteristics of asymptomatic Wolff-Parkinson-White syndrome. Eur Heart J 1993;14:511-5.
18. Goudevenos JA, Katsouras CS, Graekas G, Argiri O, Giogiakas V, Sideris DA. Ventricular pre-excitation in the general population: a study on the mode of presentation and clinical course. Heart 2000;83:29-34.
19. Todd DM, Klein GJ, Krahn AD, Skanes AC, Yee R. Asymptomatic Wolff-Parkinson-White syndrome: is it time to revisit guidelines? J Am Coll Cardiol 2003;41:245-8.