Oral Hypoglycaemic Activity of Ipomoea aquatica in Streptozotocin-induced, Diabetic Wistar Rats and Type II Diabetics

Phytotherapy Research

Volumn 17, Issue 9, 2003, Pages 1098-1100

  Malalavidhane, T S ^a   Wickramasinghe, S M D N ^b   Perera, M S A ^b   Jansz, E R ^b  

^a UNIVERSITY OF KELANIYA   (Sri Lanka)

^b UNIVERSITY OF SRI JAYEWARDENEPURA   (Sri Lanka)

Author keywords

Diabetic Wistar rats; Glucose challenge; Ipomoea aquatica; Type II diabetics

Indexed keywords

GLUCOSE; IPOMOEA AQUATICA EXTRACT; ORAL ANTIDIABETIC AGENT; STREPTOZOCIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DRUG EFFICACY; DRUG ISOLATION; GLUCOSE BLOOD LEVEL; HUMAN; IPOMOEA; IPOMOEA AQUATICA; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; ORAL GLUCOSE TOLERANCE TEST; PLANT LEAF; PLANT STEM; RAT; STREPTOZOCIN DIABETES;

ADMINISTRATION, ORAL; ANIMALS; BLOOD GLUCOSE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; HYPOGLYCEMIC AGENTS; IPOMOEA; MALE; PHYTOTHERAPY; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, WISTAR; STREPTOZOCIN;

IPOMOEA; IPOMOEA AQUATICA; RATTUS NORVEGICUS;

EID: 0242331635     PISSN: 0951418X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ptr.1345     Document Type: Article

References (9)

1. Atta-ur-Rahman, Zaman K. 1989. Medicinal plants with hypoglycaemic activity. J Ethnopharmacol 26(1): 1-55.
2. Hugget AS, Nixon DA. 1957. Use of glucose peroxidase and dianidase in the determination of blood and urinary glucose. Lancet 2; 368-370.
3. Jayaweera DMA. 1982. Medicinal Plants (Indigenous and Exotic) Used in Ceylon, Part 11. National Science Council: Sri Lanka, Colombo; 99.
4. Kumar P, Clark M. 1994. Clinical Medicine. A Textbook for Medical Students and Doctors. Third Edition, SW, Saunders Company Ltd: London; 834.
5. Malalavidhana TS, Wickramasinghe SMDN, Jansz ER. 2000a. Oral hypoglycaemic effect of Ipomoea aquatica. J Ethnopharmacol, 72: 293-298.
6. Malalavidhana TS, Wickramasinghe SMDN, Jansz ER. 2000b. Effect of different fractions of Ipomoea aquatica on the blood glucose levels of Wistar rats. Chem Sri Lanka 17: 32-33.
7. Malalavidhana TS, Wickramasinghe SMDN, Jansz ER. 2001. Comparison of the oral hypoglycaemic effect of Ipomoea aquatica with tolbutamide. Phytother Res 15: 635-637.
8. Serasinghe S, Serasinghe P, Yamazaki H, et al. 1990. Oral hypoglycaemic effect of Salacia reticulata in the streptozotocin-induced diabetic rat. Phytother Res 4(5): 205-296.
9. Percentage increase in the serum glucose concentrations of Type II diabetics treated (Test) and not treated (Control) with Ipomoea aquatica n = 20 * significantly lower than the Control at p = 0.001 (29.4% reduction).