Development and validation of a real-time PCR assay for the detection and quantitation of p53 recombinant adenovirus in clinical samples from patients treated with Ad5CMV-p53 (INGN 201)

Journal of Virological Methods

Volumn 114, Issue 1, 2003, Pages 55-64

  Saulnier, Patrick ^a   Vidaud, Michel ^b   Gautier, Eric ^a   Motté, Nelly ^a   Bellet, Dominique ^a   Escudier, Bernard ^a   Wilson, Deborah ^c   Yver, Antoine ^d  

^a INSTITUT GUSTAVE ROUSSY   (France)

^b FACULTÉ DES SCIENCES PHARMACEUTIQUES ET BIOLOGIQUES   (France)

^c Introgen Therapeutics Inc   (United States)

^d SANOFI   (France)

Author keywords

Cancer; Gene therapy; p53 Recombinant adenovirus; Real time polymerase chain reaction

Indexed keywords

ADVEXIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ADENOVIRUS; ANALYTIC METHOD; ARTICLE; CALIBRATION; CANCER PATIENT; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; HEAD AND NECK CARCINOMA; HUMAN; INJECTION; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; VALIDATION PROCESS; VIRAL GENE THERAPY; VIRUS DETECTION;

ADENOVIRIDAE;

EID: 0242331246     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2003.08.012     Document Type: Article

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