Nonopioid Receptor-Mediated Effects of U-50,488H on [Ca2+] i and Extracellular Dopamine in PC12 Cells

Journal of Neuroscience Research

Volumn 74, Issue 4, 2003, Pages 598-604

  Chudapongse, Nuannoi ^a   Kim, Seong Youl ^a   Sasaki, Kenroh ^a   Kramer, Robert E ^a   Ho, Ing K ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

Author keywords

opioid receptor agonist; Calcium; Dopamine; PC12 cells; U 50,488H

Indexed keywords

3,4 DICHLORO N METHYL N [2 (1 PYRROLIDINYL)CYCLOHEXYL]BENZENEACETAMIDE METHANESULFONATE; 3,4 DIHYDROXYPHENYLACETIC ACID; CALCIUM; DOPAMINE; KAPPA OPIATE RECEPTOR; KAPPA OPIATE RECEPTOR AGONIST; KAPPA OPIATE RECEPTOR ANTAGONIST; NORBINALTORPHIMINE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL STIMULATION; CELL STRAIN; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; DOPAMINE METABOLISM; DRUG EFFECT; DRUG SELECTIVITY; EXOCYTOSIS; EXTRACELLULAR SPACE; MEASUREMENT; METABOLITE; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RAT;

3,4-DICHLORO-N-METHYL-N-(2-(1-PYRROLIDINYL)-CYCLOHEXYL)-BENZENEACETAMIDE, (TRANS)-ISOMER; 3,4-DIHYDROXYPHENYLACETIC ACID; ANALGESICS, NON-NARCOTIC; ANALYSIS OF VARIANCE; ANIMALS; CALCIUM; DOPAMINE; DOSE-RESPONSE RELATIONSHIP, DRUG; INTRACELLULAR FLUID; NALTREXONE; NARCOTIC ANTAGONISTS; PC12 CELLS; RATS; RECEPTORS, OPIOID, KAPPA;

EID: 0242330830     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10801     Document Type: Article

References (38)

1. Bradford MM. 1976. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254.
2. Burns DL, Hewlett EL, Moss J, Vaughan M. 1983. Pertussis toxin inhibits enkephalin stimulation of GTPase of NG108-15 cells. J Biol Chem 258:1435-1438.
3. 2+ channels to release adenosine from spinal cord synaptosomes. J Neurochem 60:894-901.
4. Clow DW, Jhamandas K. 1988. Effects of a kappa-receptor agonist, U-50,488H, on the release of endogenous brain dopamine. Can J Physiol Pharmacol 66:128-133.
5. Crain SM, Shen KF, Chalazonitis A. 1988. Opioids excite rather than inhibit sensory neurons after chronic opioid exposure of spinal cord-ganglion cultures. Brain Res 455:99-109.
6. 3H-dopamine uptake in rat striatum and nucleus accumbens. Neuropharmacology 33:221-226.
7. Dermitzaki E, Gravanis A, Venihaki M, Stournaras C, Margioris AN. 2001. Opioids suppress basal and nicotine-induced catecholamine secretion via a stabilizing effect on actin filaments. Endocrinology 142:2022-2031.
8. 3H]CGP-39653 binding to rat brain membranes. Eur J Pharmacol 271:241-244.
9. Eliav E, Herzberg U, Caudle RM. 1999. The κ-opioid agonist GR89, 696 blocks hyperalgesia and allodynia in rat models of peripheral neuritis and neuropathy. Pain 79:255-264.
10. Fields A, Gafni M, Oron Y, Sarne Y. 1995. Multiple effects of opiates on intracellular calcium amount and on calcium uptake in three neuronal cell lines. Brain Res 687:94-102.
11. Giros B, Wang YM, Suter S, McLeskey SB, Pifl C, Caron MG. 1994. Delineation of discrete domains for substrate, cocaine, and tricyclic antidepressant interactions using chimeric dopamine-norepinephrine transporters. J Biol Chem 269:15985-15988.
12. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
13. Gu H, Wall SC, Rudnick G. 1994. Stable expression of biogenic amine transporters reveals differences in inhibitor sensitivity, kinetics, and ion dependence. J Biol Chem 269:7124-7130.
14. Ho J, Mannes AJ, Dubner R, Caudle RM. 1997. Putative kappa-2 opioid agonists are antihyperalgesic in a rat model of inflammation. J Pharmacol Exp Ther 281:136-141.
15. 4, Gly-ol)-enkephalin increase the intracellular free calcium in isolated rat myocytes-effect of naloxone or pretreatment with morphine. Life Sci 48:1101-1107.
16. Itoh H, Andoh T, Watanabe I, Sasaki T, Kamiya Y, Okumura F. 2000. Dynorphins directly inhibit neuronal nicotinic acetylcholine receptors in PC12 cells. Eur J Neurosci 12:1253-1262.
17. Jin W, Lee NM, Loh HH, Thayer SA. 1992. Dual excitatory and inhibitory effects of opioids on intracellular calcium in neuroblastoma x glioma hybrid NG108-15 cells. Mol Pharmacol 42:1083-1089.
18. Jin W, Lee NM, Loh HH, Thayer SA. 1994. Opioids mobilize calcium from inositol 1,4,5-trisphosphate-sensitive stores in NG108-15 cells. J Neurosci 14:1920-1929.
19. Kantor L, Hewlett GH, Park YH, Richardson-Burns SM, Mellon MJ, Gnegy ME. 2001. Protein kinase C and intracellular calcium are required for amphetamine-mediated dopamine release via the norepinephrine transporter in undifferentiated PC12 cells. J Pharmacol Exp Ther 297:1016-1024.
20. Keren O, Gafni Y, Sarne Y. 1997. Opioids potentiate transmitter release from SK-N-SH human neuroblastoma cells by modulating N-type calcium channels. Brain Res 764:277-282.
21. Keren O, Gafni M, Sarne Y. 1999. Potentiation of transmitter release from NMB human neuroblastoma cells by kappa-opioids is mediated by N-type voltage-dependent calcium channels. Brain Res 843:193-198.
22. Makman MH, Dvorkin B, Crain SM. 1988. Modulation of adenylate cyclase activity of mouse spinal cord-ganglion explants by opioids, serotonin and pertussis toxin. Brain Res 445:303-313.
23. 2+ influx. J Neurochem 43:614-618.
24. 4 mRNA by opioid receptor agonists in PC12 cells expressing cloned μ- or κ-opioid receptors. Eur J Pharmacol 433:29-36.
25. Nestler EJ, Alreja M, Aghajanian GK. 1999. Molecular control of locus coeruleus neurotransmission. Biol Psychiatry 46:1131-1139.
26. Oka K, Andoh T, Watanabe I, Kamiya Y, Ito H. 1998. Inhibition of the neuronal nicotinic receptor-mediated current by kappa opioid receptor agonists in PC12 cells. Pflugers Arch 436:887-893.
27. Onali P, Olianas MC. 1991. Naturally occurring opioid receptor agonists stimulate adenylate cyclase activity in rat olfactory bulb. Mol Pharmacol 39:436-441.
28. 3 cells by cloned μ- and δ-opioid receptors. Mol Pharmacol 50:947-956.
29. 2+ channel and adenylyl cyclase modulation by cloned μ-opioid receptors in GH3 cells. Mol Pharmacol 47:1041-1049.
30. Sarne Y, Gafni M. 1996. Determinants of the stimulatory opioid effect on intracellular calcium in SK-N-SH and NG108-15 neuroblastoma. Brain Res 722:203-206.
31. Tai KK, Bian CF, Wong TM. 1992. κ-Opioid receptor stimulation increases intracellular free calcium in isolated rat ventricular myocytes. Life Sci 51:909-913.
32. Takekoshi K, Ishii K, Kawakami Y, Isobe K, Nakai T. 2000. κ-Opioid inhibits catecholamine biosynthesis in PC12 rat pheochromocytoma cell. FEBS Lett 477:273-277.
33. Tallent M, Dichter MA, Bell GI, Reisine T. 1994. The cloned kappa opioid receptor couples to an N-type calcium current in undifferentiated PC-12 cells. Neuroscience 63:1033-1040.
34. Tang T, Kiang JG, Cox BM. 1994. Opioids acting through delta receptors elicit a transient increase in the intracellular free calcium concentration in dorsal root ganglion-neuroblastoma hybrid ND8-47 cells. J Pharmacol Exp Ther 270:40-46.
35. 2+ influx pathways couple acetylcholine receptor activation to catecholamine secretion from PC12 cells. J Neurochem 75:1583-1589.
36. 2+ mobilization in single cells of bradykinin-sensitized differentiated neuroblastoma hybridoma (NG108-15) cells. Neurosci Lett 148:93-96.
37. Venihaki M, Gravanis A, Margioris AN. 1996. Opioids inhibit dopamine secretion from PC12 rat pheochromocytoma cells in a naloxone-reversible manner. Life Sci 58:75-82.
38. Yu VC, Eiger S, Duan DS, Lameh J, Sadee W. 1990. Regulation of cyclic AMP by the μ-opioid receptor in human neuroblastoma SH-SY5Y cells. J Neurochem 55:1390-1396.