Proteolytic Cleavage of Granulocyte Colony-Stimulating Factor and its Receptor by Neutrophil Elastase Induces Growth Inhibition and Decreased Cell Surface Expression of the Granulocyte Colony-Stimulating Factor Receptor

American Journal of Hematology

Volumn 74, Issue 3, 2003, Pages 149-155

  Hunter, Melissa G ^a   Druhan, Lawrence J ^a   Massullo, Pam R ^b   Avalos, Belinda R ^a,b  

^a THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Colony stimulating factors; Granulopoiesis; Neutrophil elastase

Indexed keywords

CELL SURFACE PROTEIN; CYTOKINE; GRANULOCYTE COLONY STIMULATING FACTOR; GRANULOCYTE COLONY STIMULATING FACTOR RECEPTOR; LEUKOCYTE ELASTASE; SERINE PROTEINASE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL PROLIFERATION; CELL SURFACE; CELL VIABILITY; CONTROLLED STUDY; GENE MUTATION; GRANULOPOIESIS; GROWTH INHIBITION; MOUSE; NEUTROPENIA; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION;

ANIMALS; CELL DIVISION; CELL LINE; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; GRANULOCYTE COLONY-STIMULATING FACTOR; HUMANS; KINETICS; LEUKOCYTE ELASTASE; MICE; RECEPTORS, GRANULOCYTE COLONY-STIMULATING FACTOR; TRANSFECTION;

EID: 0242330216     PISSN: 03618609     EISSN: None     Source Type: Journal    
DOI: 10.1002/ajh.10434     Document Type: Article

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