Enhancement of Dehydroepiandrosterone Solubility and Bioavailability by Ternary Complexation with α-Cyclodextrin and Glycine

Journal of Pharmaceutical Sciences

Volumn 92, Issue 11, 2003, Pages 2177-2184

  Mora, P Corvi ^a   Cirri, M ^b   Allolio, B ^c   Carli, F ^d   Mura, P ^b  

^a Euphar Group Srl   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d Actimex Srl   (Italy)

Author keywords

Bioavailability; Complexation; Cyclodextrins; Dehydroepiandrosterone (DHEA); Dissolution; Solubility

Indexed keywords

ALPHA CYCLODEXTRIN; BIOMALTODEXTRIN; DEXTRIN; GLYCINE; MACROGOL 400; POLYMER; POVIDONE; PRASTERONE; PRASTERONE SULFATE; UNCLASSIFIED DRUG;

ADRENAL CORTEX INSUFFICIENCY; ADULT; AGED; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; COMPLEX FORMATION; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CRYSTAL STRUCTURE; DIFFERENTIAL SCANNING CALORIMETRY; DISSOLUTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG FORMULATION; DRUG SOLUBILITY; FEMALE; HORMONE SUBSTITUTION; HUMAN; RANDOMIZED CONTROLLED TRIAL; TIME; X RAY POWDER DIFFRACTION;

EID: 0242322422     PISSN: 00223549     EISSN: None     Source Type: Journal    
DOI: 10.1002/jps.10485     Document Type: Article

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