C2 monitoring in maintenance renal transplant recipients: Is it worthwhile?

Transplantation

Volumn 76, Issue 8, 2003, Pages 1236-1238

  Midtvedt, Karsten ^a,b   Fauchald, Per ^a   Bergan, Stein ^a   Høieggen, Aud ^b   Hallan, Stein ^c   Svarstad, Einar ^d   Bergrem, Harald ^e   Eriksen, Bjoern O ^f   Pfeffer, Per F ^a   Dalen, Ingvild ^a   Leivestad, Torbjoern ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^c TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^d Stavanger Hospital   (Norway)

^e HAUKELAND UNIVERSITY HOSPITAL   (Norway)

^f UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

AZATHIOPRINE; CREATININE; CYCLOSPORIN A; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; PREDNISOLONE; CYCLOSPORIN; IMMUNOSUPPRESSIVE AGENT;

ADULT; AGED; ANALYSIS OF VARIANCE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG MONITORING; ENZYME IMMUNOASSAY; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; KIDNEY ALLOGRAFT REJECTION; KIDNEY TRANSPLANTATION; LINEAR REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; NORWAY; PRIORITY JOURNAL; BLOOD; KIDNEY; MIDDLE AGED; PATHOPHYSIOLOGY; POSTOPERATIVE CARE; REGRESSION ANALYSIS;

ADULT; AGED; CREATININE; CYCLOSPORINE; FEMALE; HUMANS; IMMUNOSUPPRESSIVE AGENTS; KIDNEY; KIDNEY TRANSPLANTATION; MALE; MIDDLE AGED; POSTOPERATIVE CARE; REGRESSION ANALYSIS;

EID: 0242300598     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.TP.0000085046.39523.D5     Document Type: Article

References (10)

1. Mahalati K, Belitsky P, Sketris T, et al. Neoral monitoring by simplified sparse sampling area under the concentration-time curve: its relationship to acute rejection and cyclosporine nephrotoxicity early after kidney transplantation. Transplantation 1999; 68: 55.
2. Mahalati K, Belitsky P, West K, et al. Approaching the therapeutic window for cyclosporine in kidney transplantation: a prospective study. J Am Soc Nephrol 2001; 12: 823.
3. Canadian Neoral Renal Transplantation Study Group. Absorption profiling of cyclosporine microemulsion (Neoral) during the first 2 weeks after renal transplantation. Transplantation 2001; 72: 1024.
4. 2 monitoring strategy for optimising cyclosporin immunosuppression. BioDrugs 2001; 15: 279.
5. Kahan BD, Keown P, Levy GA, et al. Therapeutic drug monitoring of immunosuppressant drugs in clinical practice. Clin Ther 2002; 24(3): 1.
6. Clase CM, Mahalati K, Kiberd BA, et al. Adequate early cyclosporin exposure is critical to prevent renal allograft rejection: patients monitored by absorption profiling. Am J Transplant 2002; 8: 789.
7. Pfeffer P, Stefoni S, Carreno C, et al. For the MO2ARTStudy Group. Monitoring of 2-hour Neoral absorption in renal transplantation shows low incidence of acute rejection in the early post-graft period: interim results of the MO2ART study [abstract 1037]. Presented at the American Society of Transplantation Congress, Washington DC, April 16-May 1, 2002.
8. 2 monitoring in clinical practice. Transplantation 2002; 73: S12.
9. Cole E, Cattran D, O'Grady C. Conversion from C-0 to C-2 monitoring may permit optimization of long-term Neoral exposure in stable renal transplant recipients. 2001: A Transplant Odyssey. Istanbul, August 20-23, 2001.
10. 2 single point sampling to evaluate cyclosporine exposure in long-term renal transplant recipients. Transplant Proc 2001; 33: 3133.