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Volumn 334, Issue 2, 2003, Pages 215-228

Tetramerization and DNA ligase IV interaction of the DNA double-strand break repair protein XRCC4 are mutually exclusive

Author keywords

DNA repair; Non homologous end joining; Protein protein interaction; V(D)J recombination

Indexed keywords

CHROMOSOME PROTEIN; DIMER; DNA; ISOENZYME; POLYDEOXYRIBONUCLEOTIDE SYNTHASE; PROTEIN XRCC4; TETRAMER; UNCLASSIFIED DRUG;

EID: 0242289356     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2003.09.031     Document Type: Article
Times cited : (67)

References (39)
  • 1
    • 0035289717 scopus 로고    scopus 로고
    • Chromosomal stability and the DNA double-stranded break connection
    • van Gent D.C., Hoeijmakers J.H., Kanaar R. Chromosomal stability and the DNA double-stranded break connection. Nature Rev. Genet. 2:2001;196-206.
    • (2001) Nature Rev. Genet. , vol.2 , pp. 196-206
    • Van Gent, D.C.1    Hoeijmakers, J.H.2    Kanaar, R.3
  • 3
    • 0037031655 scopus 로고    scopus 로고
    • Identification of a DNA nonhomologous end-joining complex in bacteria
    • Weller G.R., Kysela B., Roy R., Tonkin L.M., Scanlan E., Della M., et al. Identification of a DNA nonhomologous end-joining complex in bacteria. Science. 297:2002;1686-1689.
    • (2002) Science , vol.297 , pp. 1686-1689
    • Weller, G.R.1    Kysela, B.2    Roy, R.3    Tonkin, L.M.4    Scanlan, E.5    Della, M.6
  • 4
    • 0032904693 scopus 로고    scopus 로고
    • The biochemistry and biological significance of nonhomologous DNA end joining: An essential repair process in multicellular eukaryotes
    • Lieber M.R. The biochemistry and biological significance of nonhomologous DNA end joining: an essential repair process in multicellular eukaryotes. Genes Cells. 4:1999;77-85.
    • (1999) Genes Cells , vol.4 , pp. 77-85
    • Lieber, M.R.1
  • 5
    • 0035997348 scopus 로고    scopus 로고
    • V(D)J recombination: Rag proteins, repair factors, and regulation
    • Gellert M. V(D)J recombination: rag proteins, repair factors, and regulation. Annu. Rev. Biochem. 71:2002;101-132.
    • (2002) Annu. Rev. Biochem. , vol.71 , pp. 101-132
    • Gellert, M.1
  • 6
    • 0032417640 scopus 로고    scopus 로고
    • A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis
    • Gao Y., Sun Y., Frank K.M., Dikkes P., Fujiwara Y., Seidl K.J., et al. A critical role for DNA end-joining proteins in both lymphogenesis and neurogenesis. Cell. 95:1998;891-902.
    • (1998) Cell , vol.95 , pp. 891-902
    • Gao, Y.1    Sun, Y.2    Frank, K.M.3    Dikkes, P.4    Fujiwara, Y.5    Seidl, K.J.6
  • 7
    • 0034690249 scopus 로고    scopus 로고
    • Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development
    • Gao Y., Ferguson D.O., Xie W., Manis J.P., Sekiguchi J., Frank K.M., et al. Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development. Nature. 404:2000;897-900.
    • (2000) Nature , vol.404 , pp. 897-900
    • Gao, Y.1    Ferguson, D.O.2    Xie, W.3    Manis, J.P.4    Sekiguchi, J.5    Frank, K.M.6
  • 8
    • 18244379848 scopus 로고    scopus 로고
    • Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions
    • Sharpless N.E., Ferguson D.O., O'Hagan R.C., Castrillon D.H., Lee C., Farazi P.A., et al. Impaired nonhomologous end-joining provokes soft tissue sarcomas harboring chromosomal translocations, amplifications, and deletions. Mol. Cell. 8:2001;1187-1196.
    • (2001) Mol. Cell , vol.8 , pp. 1187-1196
    • Sharpless, N.E.1    Ferguson, D.O.2    O'Hagan, R.C.3    Castrillon, D.H.4    Lee, C.5    Farazi, P.A.6
  • 9
    • 0033006852 scopus 로고    scopus 로고
    • Ku, a DNA repair protein with multiple cellular functions?
    • Featherstone C., Jackson S.P. Ku, a DNA repair protein with multiple cellular functions? Mutat. Res. 434:1999;3-15.
    • (1999) Mutat. Res. , vol.434 , pp. 3-15
    • Featherstone, C.1    Jackson, S.P.2
  • 10
    • 0035917489 scopus 로고    scopus 로고
    • Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency
    • Moshous D., Callebaut I., de Chasseval R., Corneo B., Cavazzana-Calvo M., Le Deist F., et al. Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. Cell. 105:2001;177-186.
    • (2001) Cell , vol.105 , pp. 177-186
    • Moshous, D.1    Callebaut, I.2    De Chasseval, R.3    Corneo, B.4    Cavazzana-Calvo, M.5    Le Deist, F.6
  • 11
    • 0029585872 scopus 로고
    • The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination
    • Li Z., Otevrel T., Gao Y., Cheng H.L., Seed B., Stamato T.D., et al. The XRCC4 gene encodes a novel protein involved in DNA double-strand break repair and V(D)J recombination. Cell. 83:1995;1079-1089.
    • (1995) Cell , vol.83 , pp. 1079-1089
    • Li, Z.1    Otevrel, T.2    Gao, Y.3    Cheng, H.L.4    Seed, B.5    Stamato, T.D.6
  • 12
    • 0032585526 scopus 로고    scopus 로고
    • Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice
    • Barnes D.E., Stamp G., Rosewell I., Denzel A., Lindahl T. Targeted disruption of the gene encoding DNA ligase IV leads to lethality in embryonic mice. Curr. Biol. 8:1998;1395-1398.
    • (1998) Curr. Biol. , vol.8 , pp. 1395-1398
    • Barnes, D.E.1    Stamp, G.2    Rosewell, I.3    Denzel, A.4    Lindahl, T.5
  • 13
    • 0032185230 scopus 로고    scopus 로고
    • DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes
    • Grawunder U., Zimmer D., Fugmann S., Schwarz K., Lieber M.R. DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes. Mol. Cell. 2:1998;477-484.
    • (1998) Mol. Cell. , vol.2 , pp. 477-484
    • Grawunder, U.1    Zimmer, D.2    Fugmann, S.3    Schwarz, K.4    Lieber, M.R.5
  • 14
    • 0032511976 scopus 로고    scopus 로고
    • Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV
    • Frank K.M., Sekiguchi J.M., Seidl K.J., Swat W., Rathbun G.A., Cheng H.L., et al. Late embryonic lethality and impaired V(D)J recombination in mice lacking DNA ligase IV. Nature. 396:1998;173-177.
    • (1998) Nature , vol.396 , pp. 173-177
    • Frank, K.M.1    Sekiguchi, J.M.2    Seidl, K.J.3    Swat, W.4    Rathbun, G.A.5    Cheng, H.L.6
  • 15
    • 0037013895 scopus 로고    scopus 로고
    • Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining
    • Chappell C., Hanakahi L.A., Karimi-Busheri F., Weinfeld M., West S.C. Involvement of human polynucleotide kinase in double-strand break repair by non-homologous end joining. EMBO J. 21:2002;2827-2832.
    • (2002) EMBO J. , vol.21 , pp. 2827-2832
    • Chappell, C.1    Hanakahi, L.A.2    Karimi-Busheri, F.3    Weinfeld, M.4    West, S.C.5
  • 16
    • 0036293744 scopus 로고    scopus 로고
    • Association of DNA polymerase mu (pol mu) with Ku and ligase IV: Role for pol mu in end-joining double-strand break repair
    • Mahajan K.N., Nick McElhinny S.A., Mitchell B.S., Ramsden D.A. Association of DNA polymerase mu (pol mu) with Ku and ligase IV: role for pol mu in end-joining double-strand break repair. Mol. Cell. Biol. 22:2002;5194-5202.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 5194-5202
    • Mahajan, K.N.1    Nick McElhinny, S.A.2    Mitchell, B.S.3    Ramsden, D.A.4
  • 17
    • 0032530658 scopus 로고    scopus 로고
    • Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells
    • Takata M., Sasaki M.S., Sonoda E., Morrison C., Hashimoto M., Utsumi H., et al. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells. EMBO J. 17:1998;5497-5508.
    • (1998) EMBO J. , vol.17 , pp. 5497-5508
    • Takata, M.1    Sasaki, M.S.2    Sonoda, E.3    Morrison, C.4    Hashimoto, M.5    Utsumi, H.6
  • 18
    • 0029817836 scopus 로고    scopus 로고
    • DNA ligase IV from HeLa cell nuclei
    • Robins P., Lindahl T. DNA ligase IV from HeLa cell nuclei. J. Biol. Chem. 271:1996;24257-24261.
    • (1996) J. Biol. Chem. , vol.271 , pp. 24257-24261
    • Robins, P.1    Lindahl, T.2
  • 19
    • 0031214080 scopus 로고    scopus 로고
    • Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV
    • Critchlow S.E., Bowater R.P., Jackson S.P. Mammalian DNA double-strand break repair protein XRCC4 interacts with DNA ligase IV. Curr. Biol. 7:1997;588-598.
    • (1997) Curr. Biol. , vol.7 , pp. 588-598
    • Critchlow, S.E.1    Bowater, R.P.2    Jackson, S.P.3
  • 20
    • 0032544413 scopus 로고    scopus 로고
    • Requirement for an interaction of XRCC4 with DNA ligase IV for wild-type V(D)J recombination and DNA double-strand break repair in vivo
    • Grawunder U., Zimmer D., Kulesza P., Lieber M.R. Requirement for an interaction of XRCC4 with DNA ligase IV for wild-type V(D)J recombination and DNA double-strand break repair in vivo. J. Biol. Chem. 273:1998;24708-24714.
    • (1998) J. Biol. Chem. , vol.273 , pp. 24708-24714
    • Grawunder, U.1    Zimmer, D.2    Kulesza, P.3    Lieber, M.R.4
  • 21
    • 0030743386 scopus 로고    scopus 로고
    • Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells
    • Grawunder U., Wilm M., Wu X., Kulesza P., Wilson T.E., Mann M., Lieber M.R. Activity of DNA ligase IV stimulated by complex formation with XRCC4 protein in mammalian cells. Nature. 388:1997;492-495.
    • (1997) Nature , vol.388 , pp. 492-495
    • Grawunder, U.1    Wilm, M.2    Wu, X.3    Kulesza, P.4    Wilson, T.E.5    Mann, M.6    Lieber, M.R.7
  • 22
    • 0033119394 scopus 로고    scopus 로고
    • DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activity
    • Modesti M., Hesse J.E., Gellert M. DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activity. EMBO J. 18:1999;2008-2018.
    • (1999) EMBO J. , vol.18 , pp. 2008-2018
    • Modesti, M.1    Hesse, J.E.2    Gellert, M.3
  • 23
    • 0032971199 scopus 로고    scopus 로고
    • Absence of DNA ligase IV protein in XR-1 cells: Evidence for stabilization by XRCC4
    • Bryans M., Valenzano M.C., Stamato T.D. Absence of DNA ligase IV protein in XR-1 cells: evidence for stabilization by XRCC4. Mutat. Res. 433:1999;53-58.
    • (1999) Mutat. Res. , vol.433 , pp. 53-58
    • Bryans, M.1    Valenzano, M.C.2    Stamato, T.D.3
  • 24
    • 0034602285 scopus 로고    scopus 로고
    • DNA ligase IV and XRCC4 form a stable mixed tetramer that functions synergistically with other repair factors in a cell-free end-joining system
    • Lee K.J., Huang J., Takeda Y., Dynan W.S. DNA ligase IV and XRCC4 form a stable mixed tetramer that functions synergistically with other repair factors in a cell-free end-joining system. J. Biol. Chem. 275:2000;34787-34796.
    • (2000) J. Biol. Chem. , vol.275 , pp. 34787-34796
    • Lee, K.J.1    Huang, J.2    Takeda, Y.3    Dynan, W.S.4
  • 26
    • 0034669204 scopus 로고    scopus 로고
    • Crystal structure of the Xrcc4 DNA repair protein and implications for end joining
    • Junop M.S., Modesti M., Guarne A., Ghirlando R., Gellert M., Yang W. Crystal structure of the Xrcc4 DNA repair protein and implications for end joining. EMBO J. 19:2000;5962-5970.
    • (2000) EMBO J. , vol.19 , pp. 5962-5970
    • Junop, M.S.1    Modesti, M.2    Guarne, A.3    Ghirlando, R.4    Gellert, M.5    Yang, W.6
  • 27
    • 0029024927 scopus 로고
    • Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination
    • Wei Y.F., Robins P., Carter K., Caldecott K., Pappin D.J., Yu G.L., et al. Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination. Mol. Cell. Biol. 15:1995;3206-3216.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3206-3216
    • Wei, Y.F.1    Robins, P.2    Carter, K.3    Caldecott, K.4    Pappin, D.J.5    Yu, G.L.6
  • 28
    • 0020585842 scopus 로고
    • Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell
    • Stamato T.D., Weinstein R., Giaccia A., Mackenzie L. Isolation of cell cycle-dependent gamma ray-sensitive Chinese hamster ovary cell. Somatic Cell Genet. 9:1983;165-173.
    • (1983) Somatic Cell Genet. , vol.9 , pp. 165-173
    • Stamato, T.D.1    Weinstein, R.2    Giaccia, A.3    Mackenzie, L.4
  • 29
    • 0027156278 scopus 로고
    • Impairment of V(D)J recombination in double-strand break repair mutants
    • Taccioli G.E., Rathbun G., Oltz E., Stamato T., Jeggo P.A., Alt F.W. Impairment of V(D)J recombination in double-strand break repair mutants. Science. 260:1993;207-210.
    • (1993) Science , vol.260 , pp. 207-210
    • Taccioli, G.E.1    Rathbun, G.2    Oltz, E.3    Stamato, T.4    Jeggo, P.A.5    Alt, F.W.6
  • 30
    • 0032537747 scopus 로고    scopus 로고
    • Role of a BRCT domain in the interaction of DNA ligase III-alpha with the DNA repair protein XRCC1
    • Taylor R.M., Wickstead B., Cronin S., Caldecott K.W. Role of a BRCT domain in the interaction of DNA ligase III-alpha with the DNA repair protein XRCC1. Curr. Biol. 8:1998;877-880.
    • (1998) Curr. Biol. , vol.8 , pp. 877-880
    • Taylor, R.M.1    Wickstead, B.2    Cronin, S.3    Caldecott, K.W.4
  • 31
    • 0032476599 scopus 로고    scopus 로고
    • Structure of an XRCC1 BRCT domain: A new protein-protein interaction module
    • Zhang X., Morera S., Bates P.A., Whitehead P.C., Coffer A.I., Hainbucher K., et al. Structure of an XRCC1 BRCT domain: a new protein-protein interaction module. EMBO J. 17:1998;6404-6411.
    • (1998) EMBO J. , vol.17 , pp. 6404-6411
    • Zhang, X.1    Morera, S.2    Bates, P.A.3    Whitehead, P.C.4    Coffer, A.I.5    Hainbucher, K.6
  • 32
    • 0030767402 scopus 로고    scopus 로고
    • Molecular genetic characterization of XRCC4 function
    • Mizuta R., Cheng H.L., Gao Y., Alt F.W. Molecular genetic characterization of XRCC4 function. Int. Immunol. 9:1997;1607-1613.
    • (1997) Int. Immunol. , vol.9 , pp. 1607-1613
    • Mizuta, R.1    Cheng, H.L.2    Gao, Y.3    Alt, F.W.4
  • 33
    • 0030887862 scopus 로고    scopus 로고
    • RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination
    • Agrawal A., Schatz D.G. RAG1 and RAG2 form a stable postcleavage synaptic complex with DNA containing signal ends in V(D)J recombination. Cell. 89:1997;43-53.
    • (1997) Cell , vol.89 , pp. 43-53
    • Agrawal, A.1    Schatz, D.G.2
  • 34
    • 0035818603 scopus 로고    scopus 로고
    • Intermediates in V(D)J recombination: A stable RAG1/2 complex sequesters cleaved RSS ends
    • Jones J.M., Gellert M. Intermediates in V(D)J recombination: a stable RAG1/2 complex sequesters cleaved RSS ends. Proc. Natl Acad. Sci. USA. 98:2001;12926-12931.
    • (2001) Proc. Natl Acad. Sci. USA , vol.98 , pp. 12926-12931
    • Jones, J.M.1    Gellert, M.2
  • 35
    • 0025977037 scopus 로고
    • Eukaryotic proteins expressed in Escherichia coli: An improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase
    • Guan K.L., Dixon J.E. Eukaryotic proteins expressed in Escherichia coli: an improved thrombin cleavage and purification procedure of fusion proteins with glutathione S-transferase. Anal. Biochem. 192:1991;262-267.
    • (1991) Anal. Biochem. , vol.192 , pp. 262-267
    • Guan, K.L.1    Dixon, J.E.2
  • 36
    • 0023049766 scopus 로고
    • Protein volumes and hydration effects. The calculations of partial specific volumes, neutron scattering matchpoints and 280 nm absorption coefficients for proteins and glycoproteins from amino acid sequences
    • Perkins S.J. Protein volumes and hydration effects. The calculations of partial specific volumes, neutron scattering matchpoints and 280 nm absorption coefficients for proteins and glycoproteins from amino acid sequences. Eur. J. Biochem. 157:1986;169-180.
    • (1986) Eur. J. Biochem. , vol.157 , pp. 169-180
    • Perkins, S.J.1
  • 37
    • 0030948789 scopus 로고    scopus 로고
    • Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination
    • Essers J., Hendriks R.W., Swagemakers S.M., Troelstra C., de Wit J., Bootsma D., et al. Disruption of mouse RAD54 reduces ionizing radiation resistance and homologous recombination. Cell. 89:1997;195-204.
    • (1997) Cell , vol.89 , pp. 195-204
    • Essers, J.1    Hendriks, R.W.2    Swagemakers, S.M.3    Troelstra, C.4    De Wit, J.5    Bootsma, D.6
  • 38
    • 0027770854 scopus 로고
    • Expression and V(D)J recombination activity of mutated RAG-1 proteins
    • Sadofsky M.J., Hesse J.E., McBlane J.F., Gellert M. Expression and V(D)J recombination activity of mutated RAG-1 proteins. Nucl. Acids Res. 21:1993;5644-5650.
    • (1993) Nucl. Acids Res. , vol.21 , pp. 5644-5650
    • Sadofsky, M.J.1    Hesse, J.E.2    McBlane, J.F.3    Gellert, M.4
  • 39
    • 0031031787 scopus 로고    scopus 로고
    • From BRCA1 to RAP1: A widespread BRCT module closely associated with DNA repair
    • Callebaut I., Mornon J.P. From BRCA1 to RAP1: a widespread BRCT module closely associated with DNA repair. FEBS Letters. 400:1997;25-30.
    • (1997) FEBS Letters , vol.400 , pp. 25-30
    • Callebaut, I.1    Mornon, J.P.2


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