Myorelaxant Effects of the Essential Oil of Croton nepetaefolius on the Contractile Activity of the Guinea-Pig Tracheal Smooth Muscle

Planta Medica

Volumn 69, Issue 9, 2003, Pages 874-877

  Caldas Magalhães, Pedro Jorge ^a   Lahlou, Saad ^b   Vasconcelos Dos Santos, Márcia Andréa ^a   Leite Pradines, Tatiana ^a   Leal Cardoso, José Henrique ^c  

^a Depto de Fisiologia e Farmacologia   (Brazil)

^b FEDERAL UNIVERSITY OF PERNAMBUCO   (Brazil)

^c STATE UNIVERSITY OF CEARÁ   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPHYLLINE; AUTACOID; CARBACHOL; ESSENTIAL OIL; HISTAMINE; MUSCLE RELAXANT AGENT; NEUROTRANSMITTER; OVALBUMIN;

ANIMAL TISSUE; ARTICLE; BREATHING MUSCLE; CONTROLLED STUDY; CROTON NEPETAEFOLIUS; DRUG POTENCY; GUINEA PIG; IC 50; MALE; MEDICINAL PLANT; MUSCLE TONE; NONHUMAN; SMOOTH MUSCLE CONTRACTILITY; SMOOTH MUSCLE FIBER; TRACHEA MUSCLE;

ANIMALS; CROTON; GUINEA PIGS; INHIBITORY CONCENTRATION 50; MUSCLE CONTRACTION; MUSCLE, SMOOTH; OVALBUMIN; PARASYMPATHOLYTICS; PHYTOTHERAPY; PLANT OILS; TRACHEA;

ANIMALIA; CAVIA PORCELLUS; CROTON; SUS SCROFA;

EID: 0242288794     PISSN: 00320943     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-43205     Document Type: Article

References (16)

1. Magalhães PJC, Criddle DN, Tavares RA, Melo EM, Mota TL, Leal-Cardoso JH. Intestinal myorelaxant and antispasmodic effects of the essential oil of Croton nepetaefolius and its constituents cineole, methyleugenol and terpineol. Phytother Res 1998; 12: 172-7
2. Leal-Cardoso JH, Fonteles MC. Pharmacological effects of essential oils of plants of the northeast of Brazil. An Acad Bras Cienc 1999; 71: 207-13
3. Lahlou S, Leal-Cardoso JH, Magalhães PJC. Essential oil of Croton nepetaefolius decreases blood pressure through an action upon vascular smooth muscle: studies in DOCA-salt hypertensive rats. Planta Med 2000; 66: 138-43
4. Lahlou S, Leal-Cardoso JH, Magalhães PJC, Coelho-de-Souza AN, Duarte GP. Cardiovascular effects of the essential oil of Croton nepetaefolius in rats: role of the autonomic nervous system. Planta Med 1999; 65: 553-7
5. 2+ regulation in airway smooth muscle contraction: do the data contradict dogma? Am J Physiol 2002; 282: L1161-78
6. Brackett LE, Shamim MT, Daly JW. Activities of caffeine, theophylline and enpropflline analogs as tracheal relaxants. Biochem Pharmacol 1990; 39: 1897-1904
7. Wills-Karp M, Gilmour MI. Increased cholinergic antagonism underlies impaired beta-adrenergic response in ovalbumin-sensitized guinea-pigs. J Appl Physiol 1993; 74: 2729-35
8. Christensen MM, Keith I, Rhodes PR, Graziano FM, Madsen PO, Bruskewitz RC et al. A guinea pig model for study of bladder mast cell function: histamine release and smooth muscle contraction. J Urol 1990; 144: 1293-1300
9. 1 or IgE antibodies. Am Rev Respir Dis 1985; 131: 260-6
10. Abdon AP, Leal-Cardoso JH, Coelho-de-Souza AN, Morais SM, Santos CF. Antinociceptive effects of the essential oil of Croton nepetaefolius on mice. Braz J Med Biol Res 2002; 35: 1215-9
11. Cox JSG. Disodium cromoglycate (FPL 670) ("Intal"): a specific inhibitor of reaginic antibody-antigen mechanisms. Nature 1967; 216: 1328-9
12. Hodgkin AL, Huxley AF. A quantitative description of membrane current and its application to conduction and excitation in nerve. J Physiol 1952; 117: 500-44
13. Rembold CM. Electromechanical and pharmacomechanical coupling. In Bárány M, editor. Biochemistry of Smooth Muscle Contraction Academic Press, New York, NY: 1996: pp. 227-41
14. Kamm KE, Grange RW. Calcium sensitivity of contraction. In: Bárány M, editor. Biochemistry of Smooth Muscle Contraction Academic Press, New York, NY: 1996: pp. 355-65
15. Craveiro AA, Matos FJA, Alencar JW. Simple and inexpensive steam-generator for essential oils extraction. J Chem Educ 1976; 53: 562
16. Craveiro AA, Fernandes AG, Andrade CHS, Matos FJA, Alencar JW, Machado MIL. Óleos essencias de plantas do nordeste. Edições UFC, Brazil Fortaleza, CE: 1981: p. 103