Studies of the Association Between Angiotensinogen Gene Regulation and Cytokines in Essential Hypertension

Acta Genetica Sinica

Volumn 30, Issue 10, 2003, Pages 978-982

  Wang, Ai Ling ^a   Yu, Yuan Xun ^b   Xu, Yan ^a   Liu, Ping ^b   Chen, Zi Ping ^a   Zhang, Li ^b   Wu, Ji Xiong ^a   Sun, Guo Mei ^b   Chen, Sen ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b Center of Medical Genetics of Anhui Province   (China)

Author keywords

Angiotensinogen gene; Cytokine; Essential hypertension; Polymerase chain reaction

Indexed keywords

ANGIOTENSINOGEN; CYTOKINE; INTERLEUKIN 1; INTERLEUKIN 6; TUMOR NECROSIS FACTOR;

ADULT; AGE; ALLELE; ANGIOTENSINOGEN GENE; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; ESSENTIAL HYPERTENSION; GENE; GENE CONTROL; GENE FREQUENCY; GENETIC POLYMORPHISM; GENETIC TRANSCRIPTION; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; POLYMERASE CHAIN REACTION; RESTRICTION MAPPING; RISK FACTOR;

ADULT; AGED; ALLELES; ANGIOTENSINOGEN; CYTOKINES; DNA; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; HYPERTENSION; INTERLEUKIN-1; INTERLEUKIN-6; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0242267496     PISSN: 03794172     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Brasier A R, LI Jun-Yi. Mechanisms for the inducible control of AGT gene transcription. Hypertension, 1996, 27(3 pt 2):465-475.
2. Brasier A R, Han Y, Sherman C T. Transcriptional regulation of angiotensinogen gene expression. Vitam Horm, 1999, 57:217-247.
3. Ishigami T, Umemura S. Angiotensinogen gene. Nippon Rinsho, 2000, 58(Suppl 1):507-510.
4. Ruben S M, Narayanan R, Klement J F, Chen C H, Rosen C A. Functional characterization of the NF-Kappa BP65 transcriptional activator and an alternatively spliced derivatire. Molcell Biol, 1992, 12(2): 444-454.
5. Ishigami T, Umemura S, Wamoto T. Molecular variant of angiotensinogen gene is associated with coronary atherosclerosis. Circulation, 1995, 91:951-954.
6. Lieb K, Kaltschmidt C, Kaltschmidt B, Baeuerle P A, Berger M, Bauer J, Fiebich B L. Interleukin-1 beta uses common and distinct signaling pathways for induction of the interleukin-6 and tumor necrosis factor alpha genes in the human astrocytoma cell line U373. J Neurochem, 1996, 66(4):1496-1503.
7. Han Y, Runge M S, Brasier A R. Angiotensin II induces interleukin-6 transcription in vascular smooth muscle cells through pleiotropic activation of nuclear factor-kappa B transcription factors. Circ Res, 1999, 84(6):695-703.
8. Brasier A R, Li J, Wimbish K A. Tumor necrosis factor activates angiotensinogen gene expression by the Rel A transactivator. Hypertension, 1996, 27(4):1009-1017.
9. Ron D, Brasier A R, Wright K A, Habener J F. The permissive role of glucocorticoids on interleukin-1 stimulation of angiotensinogen gene transcription is mediated by an interaction between inducible enhancers. Mol Cell Biol, 1990, 10(8):4389-4395.
10. Janssen-Heininger Y M, Poynter M E, Baeuerle P A. Recent advances towards understanding redox mechanisms in the activation of nuclear factor kappaB. Free Radic Biol Med, 2000, 28(9):1317-1327.
11. Kumar A, Nugent K, Kalakunja A, Pirtle F. Severe acidosis in a patient with type 2 diabetes mellitus, hypertension, and renal failure. Chest, 2003, 123(5):1726-1729.
12. Brasier A R, Kumar A. Identification of a novel determinant for basic domain-Lencine Eipper (bzzp) DNA-binding activity in the acute-phase inducible nudear factor-interleukin 6 transcription factor. J Biol Chem, 1994, 269(14):10341-10351.