Rapid i.v. loading with phenytoin with subsequent dose adaptation using non-steady-state serum levels and a Bayesian forecasting computer program to predict maintenance doses

Journal of Clinical Pharmacy and Therapeutics

Volumn 28, Issue 5, 2003, Pages 385-393

  Martinelli, E F ^a,b   Muhlebach S F ^a  

^a Kantonsspital ^*  (Switzerland)

^b Spitalapotheke Berner Oberland   (Switzerland)

Author keywords

Bayesian forecasting; Dose individualization; Loading regimen; Pharmacokinetics; Phenytoin

Indexed keywords

CLONAZEPAM; OMEPRAZOLE; PHENYTOIN; RANITIDINE;

ADULT; AGED; ARTICLE; BAYES THEOREM; BODY WEIGHT; CLINICAL TRIAL; COMPUTER PROGRAM; DRUG BLOOD LEVEL; DRUG HYPERSENSITIVITY; EPILEPSY; FEMALE; HUMAN; HYPOTENSION; MAINTENANCE DRUG DOSE; MAJOR CLINICAL STUDY; MALE; PROSPECTIVE STUDY; RELIABILITY;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTICONVULSANTS; BAYES THEOREM; COMPUTERS; FEMALE; HOSPITALIZATION; HUMANS; INFUSIONS, INTRAVENOUS; MALE; MIDDLE AGED; PHENYTOIN;

EID: 0242267108     PISSN: 02694727     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0269-4727.2003.00506.x     Document Type: Article

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