Effect of polyamines on in vitro platelet aggregation and in vivo thrombus formation

Cardiovascular Radiation Medicine

Volumn 3, Issue 3-4, 2002, Pages 213-220

  Pakala, Rajbabu ^a,b  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b WASHINGTON HOSPITAL CENTER   (United States)

Author keywords

Aggregation; Platelets; Polyamines; Spermine; Thrombosis

Indexed keywords

POLYAMINE; SPERMINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLEEDING TENDENCY; CONTROLLED STUDY; CORONARY ARTERY; CORONARY ARTERY BLOOD FLOW; DOSE RESPONSE; ELECTRIC CURRENT; EVALUATION; EXPERIMENTAL MODEL; HEART INFARCTION; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; SKIN INCISION; SPECIES COMPARISON; THROMBOCYTE AGGREGATION; THROMBOGENESIS; THROMBUS; TURBIDIMETRY;

EID: 0142258752     PISSN: 15221865     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1522-1865(03)00097-0     Document Type: Article

References (46)

1. Bachrach U. Function of naturally occurring polyamines. 1973;Academic Press, New York.
2. Tabor C.W., Tabor H. Polyamines. Annu Rev Biochem. 53:1984;749-790.
3. Balasundaram D., Tabor C.W., Tabor H. Spermidine or spermine is essential for the aerobic growth of Saccharomyces cerevisiae. Proc Natl Acad Sci. 88:1991;5872-5876.
4. Poulin R., Wechter R.S., Pegg A.E. An early enlargement of the putrescine pool is required for growth in L1210 mouse leukemia cells under hypo osmotic stress. J Biol Chem. 266:1991;6142-6151.
5. Chandra R., Beri R., Misra U.K. Effect of spermine on membranolytic effect of vitamin A in rats. Int J Vitam Nutr Res. 58:1988;13-15.
6. Kvietys P.R., Specian R.D., Cepinskas G. Polyamines attenuate jejunal mucosal injury induced by oleic acid. Am J Physiol. 263:1992;G224-G229.
7. Agam G., Gartner T.K., Levin A. Inhibition of platelet aggregation and endogenous lecithin activity by oligoamines. Thrombos Res. 33:1984;245-257.
8. Ganguly P., Bradford H.R. Inhibition of platelet aggregation by primary amines. Evidence for a possible role of membrane-associated calcium. Biochim Biophys Acta. 714:1982;192-199.
9. Joseph S., Krishnamurthi S., Kakkar V.V. Effect of the polyamine-spermine on agonist-induced human platelet activation-specific inhibition of "aggregation independent" events induced by thrombin, but not by collagen, thromboxane mimetic, phorbol ester or calcium ionophore. Thromb Haemost. 57:1987;191-195.
10. Rennert O., Buehler B., Miale T., Lawson D. Polyamines and platelet aggregation. Life Sci. 19:1976;257-264.
11. Joseph S., Krishnamurthi S. Effect of the polyamine spermine on human platelet activation. Thromb Haemost. 54:1985;135-139.
12. Houston D.S., Gerrard J.M., McCrea J., Glover S., Butler A.M. The influence of amines on various platelet responses. Biochim Biophys Acta. 734:1983;267-273.
13. Pales J.L., Lopez A., Vidal S. Effects of polyamines on platelet aggregation. Scand J Haematol. 32:1984;241-244.
14. Israels S.J., Gerrard J.M., Robinson P. Differential effects of spermine on aggregation, inositol phosphate formation and protein phosphorylation in human platelets in response to thrombin, arachidonic acid and lysophosphatidic acid. Biochim Biophys Acta. 883:1986;247-252.
15. Mendez J.D., Zarzosa E. Inhibition of platelet activation by L-arginine and polyamines in alloxan treated rats. Biochem Mol Biol Int. 43:1997;311-318.
16. Via L.D., Francesconi M., Mazzucato M., Pradella P., De Marco L., Vecchia F.D., Rascio N., Deana R. On the mechanism of the spermine-exerted inhibition on α-thrombin-induced platelet activation. Thromb Res. 98:2000;59-71.
17. Peerschke E.I.B. The platelet fibrinogen receptor. Semin Hematol. 22:1985;241-259.
18. Gartner T.K., Gerrard J.M., White J.G., Williams D.C. Fibrinogen is the receptor for the endogenous lectin of human platelets. Nature. 289:1981;263-269.
19. Kinlough-Rathbone R.L., Packham M.A., Mustard J.F. Effects of amino-sugars on platelet aggregation and fibrinogen binding. Thromb Haemost. 52:1984;75-80.
20. Kuo B., Korner G., Dryjski M., Bjornsson T.D. Role of polyamines in the synthesis of plasminogen activator from bovine aortic endothelial cells. J Cell Physiol. 137:1988;192-198.
21. Chideckel E.W., Dedhia H.H., Fedan J.S., Teba L., Jain A. Spermine decreases peripheral vascular resistance in the dog. Cardiovasc Res. 20:1986;931-934.
22. Onodeza K., Unemoto T., Miyaki K., Ayashie M.I. Pharmacological studies on polyamines: 1. Relaxing effect of spermine and spermidine on guinea pig ilium contracted by 5-hydroxytryptamine and nicotine. Arch Int Pharmacol Ther. 174:1968;491-494.
23. Benedict C.R., Ryan J., Wolitzky B., Ramos R., Gerlach M., Tijburg P., Stern D. Active site-blocked factor IXa prevents intravascular thrombus formation in the coronary vasculature without inhibiting extravascular coagulation in a canine thrombosis model. J Clin Invest. 88:1991;1760-1765.
24. Benedict C.R., Ryan J., Todd J., Kuwabara K., Tijburg P., Cartwright J., Stern D. Active site-blocked factor Xa prevents thrombus formation in the coronary vasculature in parallel with inhibition of extravascular coagulation in a canine thrombosis model. Blood. 81:1993;2059-2066. Apr 15.
25. Berridge M.J. Inositol trisphosphate and diacylglycerol: two interacting second messengers. Annu Rev Biochem. 56:1987;159-193.
26. Farago A., Nishizuka Y. Protein kinase C in transmembrane signalling. FEBS Lett. 268:1990;350-354.
27. Bratton D.L. Polyamine inhibition of transbilayer movement of plasma membrane phospholipids in the erythrocyte ghost. J Biol Chem. 269:1994;22517-22523.
28. Sulpice J.C., Moreau C., Devaux P.F., Zachowski A., Giraud F. Antagonist effect of Ca2+ and spermine on phosphatidylinositol 4,5-bisphosphate-mediated transmembrane redistribution of phospholipids in large unilamellar vesicles and in erythrocytes. Biochemistry. 35:1996;13345-13352.
29. Meers P., Hong K., Bentz J., Papahadjopoulos D. Spermine as a modulator of membrane fusion: interactions with acidic phospholipids. Biochemistry. 25:1986;3109-3118.
30. Tadolini B., Hakim G. Interaction of polyamines with phospholipids: spermine and Ca2+ competition for phosphatidylserine containing liposomes. Adv Exp Med Biol. 250:1988;481-490.
31. Sechi A.M., Gabrini L., Landi L., Pasquali P., Lenaz G. Inhibition of phospholipase A2 and phospholipase C by polyamines. Arch Biochem Biophys. 186:1978;248-254.
32. Wojcikiewicz R.J., Fain J.N. Polyamines inhibit phospholipase C-catalysed polyphosphoinositide hydrolysis. Studies with permeabilized GH3 cells. Biochem J. 255:1988;1015-1021.
33. Ohkubo Y. Spermine modulates calcium flux through the rat erythrocyte membrane. Biol Pharm Bull. 20:1997;153-157.
34. Rustenbeck I., Eggers G., Reiter H., Munster W., Lenzen S. Polyamine modulation of mitochondrial calcium transport: I. Stimulatory and inhibitory effects of alipatic polyamines, aminoglucosides and other polyamine analogues on mitochondrial calcium uptake. Biochem Pharmacol. 56:1998;977-985.
35. Qi D.F., Schatzman R.C., Mazzei G.J., Turner R.S., Raynor R.L., Liao S., Kuo J.F. Polyamines inhibit phospholipid-sensitive and calmodulin-sensitive Ca2+-dependent protein kinases. Biochem J. 213:1983;281-288.
36. Combest W.L., Gilbert L.I. Polyamines modulat multiple protein phosphorylation pathways in the insecet prothoracic gland. Mol Cell Endocrinol. 83:1992;11-19.
37. Sjoholm A., Honkanen R.E. Polyamines regulate serine/threonine protein phosphatases in insulin-secreting cells. Pancreas. 20:2000;32-37.
38. Seymour J.L., Henzel W.J., Nevins B., Stults J.T., Lazarus R.A. Decorsin. A potent glycoprotein IIb-IIIa antagonist and platelet aggregation inhibitor from the leech Macrobdella decora. J Biol Chem. 265:1990;10143-10147.
39. Reshe K., Seidel T. Platelet aggregation inhibiting and anticoagulant effects of oligoamines XXII oligoamines with fluorescent properties: Part A. Fluorescent bridged nitrogen functions. Arch Pharm (Weinheim). 325:1992;235-239.
40. Rehse K., Kesselhut A., Schein V., Leissring S. Platelet aggregation inhibiting and anticoagulant effect of oligoamines XIX branched aliphatic and alicyclic triamines and tetramines. Arch Pharm (Weinheim). 324:1991;243-248.
41. Rehse K., Puchert E., Leissring S. Platelet aggregation inhibiting and anticoagulant effects of oligoamines XII. Arch Pharm (Weinheim). 323:1990;287-294.
42. Rehse K., Kesselhut A., Schein V., Kampfe M., Rose B., Unsold E. Platelet aggregation inhibiting and anticoagulant effects of oligoamines XX: antithrombotic effect of selected oligoamines in rats. Arch Pharm (Weinheim). 324:1991;301-305.
43. Atkinson P.M., Taylor D.I., Chetty N. Inhibition of platelet aggregation by ketamine hydrochloride. Thromb Res. 40:1985;227-234.
44. He Y., Kashiwagi K., Fukuchi J., Terao K., Shirahata A., Igarashi K. Correlation between the inhibition of cell growth by accumulated polyamines and the decrease of magnesium and ATP. Eur J Biochem. 217:1993;89-96.
45. Revuelta M.P., Cantabrana B., Hidalgo A. Pharmacological evidence for the contribution of polyamines as mediators of the transcriptional component involved in smooth muscle relaxation elicited by forskolin. Life Sci. 61:1997;2443-2454.
46. Shao Z., Mellor I.R., Brierley M.J., Harris J., Usherwood P.N. Potentiation and inhibition of nicotinic acetylcholine receptors by spermine in the TE671 human muscle cell line. J Pharmacol Exp Ther. 286:1998;1269-1276.