-
1
-
-
0036227720
-
Culprit and victim - DNA topoisomerase II
-
Kellner, U., Sehested, M., Jensen, P. B., Gieseler, F., and Rudolph, P. Culprit and victim - DNA topoisomerase II. Lancet Oncol., 3: 235-243, 2002.
-
(2002)
Lancet Oncol.
, vol.3
, pp. 235-243
-
-
Kellner, U.1
Sehested, M.2
Jensen, P.B.3
Gieseler, F.4
Rudolph, P.5
-
2
-
-
0027999113
-
Schedule-dependent topoisomerase II-inhibiting drugs
-
Joel, S. P., and Slevin, M. L. Schedule-dependent topoisomerase II-inhibiting drugs. Cancer Chemother. Pharmacol., 34: S84-S88, 1994.
-
(1994)
Cancer Chemother. Pharmacol.
, vol.34
-
-
Joel, S.P.1
Slevin, M.L.2
-
3
-
-
0021986492
-
Bioavailability and pharmacokinetics of etoposide (VP-16)
-
Smyth, R. D., Pfeffer, M., Scalzo, A., and Comis, R. L. Bioavailability and pharmacokinetics of etoposide (VP-16). Semin. Oncol., 12: 48-51, 1985.
-
(1985)
Semin. Oncol.
, vol.12
, pp. 48-51
-
-
Smyth, R.D.1
Pfeffer, M.2
Scalzo, A.3
Comis, R.L.4
-
4
-
-
0022608672
-
Pharmacokinetics of etoposide in patients with abnormal renal and hepatic function
-
D'Incalci, M., Rossi, C., Zucchetti, M., Urso, R., Cavalli, F., Mangioni, C., Willems, Y., and Sessa, C. Pharmacokinetics of etoposide in patients with abnormal renal and hepatic function. Cancer Res., 46: 2566-2571, 1986.
-
(1986)
Cancer Res.
, vol.46
, pp. 2566-2571
-
-
D'Incalci, M.1
Rossi, C.2
Zucchetti, M.3
Urso, R.4
Cavalli, F.5
Mangioni, C.6
Willems, Y.7
Sessa, C.8
-
5
-
-
0028277792
-
A randomized trial of two etoposide schedules in small-cell lung cancer: The influence of pharmacokinetics on efficacy and toxicity
-
Clark, P. I., Slevin, M. L., Joel, S. P., Osborne, R. J., Talbot, D. C., Johnson, P. W., Reznek, R., Masud, T., Gregory, W., and Wrigley, P. F. A randomized trial of two etoposide schedules in small-cell lung cancer: the influence of pharmacokinetics on efficacy and toxicity. J. Clin. Oncol., 12: 1427-1435, 1994.
-
(1994)
J. Clin. Oncol.
, vol.12
, pp. 1427-1435
-
-
Clark, P.I.1
Slevin, M.L.2
Joel, S.P.3
Osborne, R.J.4
Talbot, D.C.5
Johnson, P.W.6
Reznek, R.7
Masud, T.8
Gregory, W.9
Wrigley, P.F.10
-
6
-
-
8944246796
-
Therapeutic monitoring of continuous infusion etoposide in small-cell lung cancer
-
Joel, S. P., Ellis, P., O'Byrne, K., Papamichael, D., Hall, M., Penson, R., Nicholls, S., O'Donnell, C., Constantinou, A., Woodhull, J., Nicholson, M., Smith, I., Talbot, D., and Slevin, M. Therapeutic monitoring of continuous infusion etoposide in small-cell lung cancer. J. Clin. Oncol., 14: 1903-1912, 1996.
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 1903-1912
-
-
Joel, S.P.1
Ellis, P.2
O'Byrne, K.3
Papamichael, D.4
Hall, M.5
Penson, R.6
Nicholls, S.7
O'Donnell, C.8
Constantinou, A.9
Woodhull, J.10
Nicholson, M.11
Smith, I.12
Talbot, D.13
Slevin, M.14
-
7
-
-
0025966386
-
The clinical pharmacology of etoposide
-
Slevin, M. L. The clinical pharmacology of etoposide. Cancer (Phila.), 67: 319-329, 1991.
-
(1991)
Cancer (Phila.)
, vol.67
, pp. 319-329
-
-
Slevin, M.L.1
-
8
-
-
0028798952
-
Pharmacokinetics and pharmacodynamics of prolonged oral etoposide in women with metastatic breast cancer
-
Millward, M. J., Newell, D. R., Yuen, K., Matthews, J. P., Balmanno, K., Charlton, C. J., Gumbrell, L., Lind, M. J., Chapman, F., Proctor, M., et al. Pharmacokinetics and pharmacodynamics of prolonged oral etoposide in women with metastatic breast cancer. Cancer Chemother. Pharmacol., 37: 161-167, 1995.
-
(1995)
Cancer Chemother. Pharmacol.
, vol.37
, pp. 161-167
-
-
Millward, M.J.1
Newell, D.R.2
Yuen, K.3
Matthews, J.P.4
Balmanno, K.5
Charlton, C.J.6
Gumbrell, L.7
Lind, M.J.8
Chapman, F.9
Proctor, M.10
-
9
-
-
0028838201
-
Pharmacological attempts to improve the bioavailability of oral etoposide
-
Joel, S. P., Clark, P. I., Heap, L., Webster, L., Robbins, S., Craft, H., and Slevin, M. L. Pharmacological attempts to improve the bioavailability of oral etoposide. Cancer Chemother. Pharmacol., 37: 125-133, 1995.
-
(1995)
Cancer Chemother. Pharmacol.
, vol.37
, pp. 125-133
-
-
Joel, S.P.1
Clark, P.I.2
Heap, L.3
Webster, L.4
Robbins, S.5
Craft, H.6
Slevin, M.L.7
-
10
-
-
0028144884
-
Clinical and pharmacokinetic overview of parenteral etoposide phosphate
-
Schacter, L. P., Igwemezie, L. N., Seyedsadr, M., Morgenthien, E., Randolph, J., Albert, E., and Santabarbara, P. Clinical and pharmacokinetic overview of parenteral etoposide phosphate. Cancer Chemother. Pharmacol., 34: S58-S63, 1994.
-
(1994)
Cancer Chemother. Pharmacol.
, vol.34
-
-
Schacter, L.P.1
Igwemezie, L.N.2
Seyedsadr, M.3
Morgenthien, E.4
Randolph, J.5
Albert, E.6
Santabarbara, P.7
-
11
-
-
0030464546
-
Early studies of etoposide phosphate, a water-soluble prodrug
-
Budman, D. R. Early studies of etoposide phosphate, a water-soluble prodrug. Semin. Oncol., 23: 8-14, 1996.
-
(1996)
Semin. Oncol.
, vol.23
, pp. 8-14
-
-
Budman, D.R.1
-
12
-
-
0028266991
-
Clinical activity of chronic oral etoposide in previously treated metastatic breast cancer
-
Martin, M., Lluch, A., Casado, A., Santabarbara, P., Adrover, E., Valverde, J. J., Lopez-Martin, J. A., Rodriguez-Lescure, A., Azagra, P., Garcia-Conde, J., et al. Clinical activity of chronic oral etoposide in previously treated metastatic breast cancer. J. Clin. Oncol., 12: 986-991, 1994.
-
(1994)
J. Clin. Oncol.
, vol.12
, pp. 986-991
-
-
Martin, M.1
Lluch, A.2
Casado, A.3
Santabarbara, P.4
Adrover, E.5
Valverde, J.J.6
Lopez-Martin, J.A.7
Rodriguez-Lescure, A.8
Azagra, P.9
Garcia-Conde, J.10
-
13
-
-
0028203706
-
Chronic oral etoposide in advanced breast cancer
-
Palombo, H., Estape, J., Vinolas, N., Grau, J. J., Mane, J. M., Daniels, M., and Mellado, B. Chronic oral etoposide in advanced breast cancer. Cancer Chemother. Pharmacol., 33: 527-529, 1994.
-
(1994)
Cancer Chemother. Pharmacol.
, vol.33
, pp. 527-529
-
-
Palombo, H.1
Estape, J.2
Vinolas, N.3
Grau, J.J.4
Mane, J.M.5
Daniels, M.6
Mellado, B.7
-
14
-
-
0028867544
-
Phase II study of oral etoposide for patients with advanced breast cancer
-
Atienza, D. M., Vogel, C. L., Trock, B., and Swain, S. M. Phase II study of oral etoposide for patients with advanced breast cancer. Cancer (Phila.), 76: 2485-2490, 1995.
-
(1995)
Cancer (Phila.)
, vol.76
, pp. 2485-2490
-
-
Atienza, D.M.1
Vogel, C.L.2
Trock, B.3
Swain, S.M.4
-
15
-
-
0028962385
-
Second-line chemotherapy with long-term low-dose oral etoposide in patients with advanced breast cancer
-
Bontenbal, M., Planting, A. S., Verweij, J., de Wit, R., Kruit, W. H., Stoter, G., and Klijn, J. G. Second-line chemotherapy with long-term low-dose oral etoposide in patients with advanced breast cancer. Breast Cancer Res. Treat., 34: 185-189, 1995.
-
(1995)
Breast Cancer Res. Treat.
, vol.34
, pp. 185-189
-
-
Bontenbal, M.1
Planting, A.S.2
Verweij, J.3
De Wit, R.4
Kruit, W.H.5
Stoter, G.6
Klijn, J.G.7
-
16
-
-
0029837372
-
Daily oral etoposide in metastatic breast cancer
-
Neskovic-Konstantinovic, Z. B., Bosnjak, S. M., Radulovic, S. S., and Mitrovic, L. B. Daily oral etoposide in metastatic breast cancer. Anticancer Drugs, 7: 543-547, 1996.
-
(1996)
Anticancer Drugs
, vol.7
, pp. 543-547
-
-
Neskovic-Konstantinovic, Z.B.1
Bosnjak, S.M.2
Radulovic, S.S.3
Mitrovic, L.B.4
-
17
-
-
0031755080
-
Daily oral etoposide in patients with heavily pretreated metastatic breast cancer
-
Pusztai, L., Walters, R. S., Valero, V., Theriault, R. L., and Hortobagyi, G. N. Daily oral etoposide in patients with heavily pretreated metastatic breast cancer. Am. J. Clin. Oncol., 21: 442-446, 1998.
-
(1998)
Am. J. Clin. Oncol.
, vol.21
, pp. 442-446
-
-
Pusztai, L.1
Walters, R.S.2
Valero, V.3
Theriault, R.L.4
Hortobagyi, G.N.5
-
18
-
-
0024590818
-
Cisplatin and etoposide: An effective treatment for refractory breast carcinoma
-
Cox, E. B., Burton, G. V., Olsen, G. A., and Vugrin, D. Cisplatin and etoposide: an effective treatment for refractory breast carcinoma. Am. J. Clin. Oncol., 12: 53-56, 1989.
-
(1989)
Am. J. Clin. Oncol.
, vol.12
, pp. 53-56
-
-
Cox, E.B.1
Burton, G.V.2
Olsen, G.A.3
Vugrin, D.4
-
19
-
-
0026087138
-
Cisplatin and etoposide as first-line chemotherapy for metastatic breast carcinoma: A prospective randomized trial of the Italian Oncology Group for Clinical Research
-
Cocconi, G., Bisagni, G., Bacchi, M., Boni, C., Bartolucci, R., Ceci, G., Colozza, M. A., De Lisi, V., Lottici, R., Mosconi, A. M., et al. Cisplatin and etoposide as first-line chemotherapy for metastatic breast carcinoma: a prospective randomized trial of the Italian Oncology Group for Clinical Research. J. Clin. Oncol., 9: 664-669, 1991.
-
(1991)
J. Clin. Oncol.
, vol.9
, pp. 664-669
-
-
Cocconi, G.1
Bisagni, G.2
Bacchi, M.3
Boni, C.4
Bartolucci, R.5
Ceci, G.6
Colozza, M.A.7
De Lisi, V.8
Lottici, R.9
Mosconi, A.M.10
-
20
-
-
0028200365
-
Phase II trial of cisplatin and etoposide as first-line therapy in metastatic breast carcinoma
-
Lluch, A., Azagra, P., Cervantes, A., Munoz, M., Alberola, V., Santabarbara, P., and Garcia-Conde, J. Phase II trial of cisplatin and etoposide as first-line therapy in metastatic breast carcinoma. Oncology, 51: 352-355, 1994.
-
(1994)
Oncology
, vol.51
, pp. 352-355
-
-
Lluch, A.1
Azagra, P.2
Cervantes, A.3
Munoz, M.4
Alberola, V.5
Santabarbara, P.6
Garcia-Conde, J.7
-
21
-
-
9244241997
-
Concurrent 72-hour continuous infusion of etoposide and cisplatin in metastatic breast cancer
-
Remick, S. C., Chmura, M., Bromberg, C., Sporn, J., Healey, B., Hilstro, J., DeConti, R. C., Horton, J., Ruckdeschel, J. C., and Harper, G. R. Concurrent 72-hour continuous infusion of etoposide and cisplatin in metastatic breast cancer. Am. J. Clin. Oncol., 19: 125-131, 1996.
-
(1996)
Am. J. Clin. Oncol.
, vol.19
, pp. 125-131
-
-
Remick, S.C.1
Chmura, M.2
Bromberg, C.3
Sporn, J.4
Healey, B.5
Hilstro, J.6
DeConti, R.C.7
Horton, J.8
Ruckdeschel, J.C.9
Harper, G.R.10
-
22
-
-
0033979421
-
Clinical activity of cisplatin and prolonged oral administration of etoposide in previously treated, anthracycline-resistant, metastatic breast cancer patients: A phase II study
-
Fried, G., Stein, M. E., and Haim, N. Clinical activity of cisplatin and prolonged oral administration of etoposide in previously treated, anthracycline-resistant, metastatic breast cancer patients: a phase II study. Med. Pediatr. Oncol., 34: 10-13, 2000.
-
(2000)
Med. Pediatr. Oncol.
, vol.34
, pp. 10-13
-
-
Fried, G.1
Stein, M.E.2
Haim, N.3
-
23
-
-
0025381434
-
Evaluation of the continuous infusion of etoposide plus cisplatin in metastatic breast cancer. A collaborative North Central Cancer Treatment Group/Mayo Clinic phase II study
-
Krook, J. E., Loprinzi, C. L., Schaid, D. J., Kardinal, C. G., Mailliard, J. A., Pfeifle, D. M., Ellison, N. M., Reuter, N. F., and Nelimark, R. A. Evaluation of the continuous infusion of etoposide plus cisplatin in metastatic breast cancer. A collaborative North Central Cancer Treatment Group/Mayo Clinic phase II study. Cancer (Phila.), 65: 418-421, 1990.
-
(1990)
Cancer (Phila.)
, vol.65
, pp. 418-421
-
-
Krook, J.E.1
Loprinzi, C.L.2
Schaid, D.J.3
Kardinal, C.G.4
Mailliard, J.A.5
Pfeifle, D.M.6
Ellison, N.M.7
Reuter, N.F.8
Nelimark, R.A.9
-
24
-
-
0030030354
-
Predicting etoposide toxicity: Relationship to organ function and protein binding
-
Joel, S. P., Shah, R., Clark, P. I., and Slevin, M. L. Predicting etoposide toxicity: relationship to organ function and protein binding. J. Clin. Oncol., 14: 257-267, 1996.
-
(1996)
J. Clin. Oncol.
, vol.14
, pp. 257-267
-
-
Joel, S.P.1
Shah, R.2
Clark, P.I.3
Slevin, M.L.4
-
25
-
-
0021913882
-
High-performance liquid chromatography of etoposide in plasma and urine
-
Harvey, V. J., Joel, S. P., Johnston, A., and Slevin, M. L. High-performance liquid chromatography of etoposide in plasma and urine. J. Chromatogr., 339: 419-423, 1985.
-
(1985)
J. Chromatogr.
, vol.339
, pp. 419-423
-
-
Harvey, V.J.1
Joel, S.P.2
Johnston, A.3
Slevin, M.L.4
-
26
-
-
0031743076
-
A randomised, concentration-controlled, comparison of standard (5-day) vs. prolonged (15-day) infusions of etoposide phosphate in small-cell lung cancer
-
Joel, S., O'Byrne, K., Penson, R., Papamichael, D., Higgins, A., Robertshaw, H., Rudd, R., Talbot, D., and Slevin, M. A randomised, concentration-controlled, comparison of standard (5-day) vs. prolonged (15-day) infusions of etoposide phosphate in small-cell lung cancer. Ann. Oncol., 9: 1205-1211, 1998.
-
(1998)
Ann. Oncol.
, vol.9
, pp. 1205-1211
-
-
Joel, S.1
O'Byrne, K.2
Penson, R.3
Papamichael, D.4
Higgins, A.5
Robertshaw, H.6
Rudd, R.7
Talbot, D.8
Slevin, M.9
-
27
-
-
0019365237
-
Reporting results of cancer treatment
-
Miller, A. B., Hoogstraten, B., Staquet, M., and Winkler, A. Reporting results of cancer treatment. Cancer (Phila.), 47: 207-214, 1981.
-
(1981)
Cancer (Phila.)
, vol.47
, pp. 207-214
-
-
Miller, A.B.1
Hoogstraten, B.2
Staquet, M.3
Winkler, A.4
-
29
-
-
0030887316
-
The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues
-
Turley, H., Comley, M., Houlbrook, S., Nozaki, N., Kikuchi, A., Hickson, I. D., Gatter, K., and Harris, A. L. The distribution and expression of the two isoforms of DNA topoisomerase II in normal and neoplastic human tissues. Br. J. Cancer, 75: 1340-1346, 1997.
-
(1997)
Br. J. Cancer
, vol.75
, pp. 1340-1346
-
-
Turley, H.1
Comley, M.2
Houlbrook, S.3
Nozaki, N.4
Kikuchi, A.5
Hickson, I.D.6
Gatter, K.7
Harris, A.L.8
-
30
-
-
50549174560
-
The determination of the number of patients required in a preliminary and a follow up trial of a new chemotherapeutic agent
-
Gehan, A. The determination of the number of patients required in a preliminary and a follow up trial of a new chemotherapeutic agent. J. Chronic Dis., 13: 346-353, 1961.
-
(1961)
J. Chronic Dis.
, vol.13
, pp. 346-353
-
-
Gehan, A.1
-
31
-
-
0027970234
-
Vinorelbine is an active antiproliferative agent in pretreated advanced breast cancer patients: A phase II study
-
Gasparini, G., Caffo, O., Barni, S., Frontini, L., Testolin, A., Guglielmi, R. B., and Ambrosini, G. Vinorelbine is an active antiproliferative agent in pretreated advanced breast cancer patients: a phase II study. J. Clin. Oncol., 12: 2094-2101, 1994.
-
(1994)
J. Clin. Oncol.
, vol.12
, pp. 2094-2101
-
-
Gasparini, G.1
Caffo, O.2
Barni, S.3
Frontini, L.4
Testolin, A.5
Guglielmi, R.B.6
Ambrosini, G.7
-
32
-
-
0028042373
-
A phase multicentre, UK study of vinorelbine in advanced breast cancer
-
Twelves, C. J., Dobbs, N. A., Curnow, A., Coleman, R. E., Stewart, A. L., Tyrrell, C. J., Canney, P., and Rubens, R. D. A phase II, multicentre, UK study of vinorelbine in advanced breast cancer. Br. J. Cancer, 70: 990-993, 1994.
-
(1994)
Br. J. Cancer
, vol.70
, pp. 990-993
-
-
Twelves, C.J.1
Dobbs, N.A.2
Curnow, A.3
Coleman, R.E.4
Stewart, A.L.5
Tyrrell, C.J.6
Canney, P.7
Rubens R.D. II8
-
33
-
-
0035476911
-
Multicenter, phase II study of capecitabine in taxane-pretreated metastatic breast carcinoma patients
-
Blum, J. L., Dieras, V., Lo Russo, P. M., Horton, J., Rutman, O., Buzdar, A., and Osterwalder, B. Multicenter, phase II study of capecitabine in taxane-pretreated metastatic breast carcinoma patients. Cancer (Phila.), 92: 1759-1768, 2001.
-
(2001)
Cancer (Phila.)
, vol.92
, pp. 1759-1768
-
-
Blum, J.L.1
Dieras, V.2
Lo Russo, P.M.3
Horton, J.4
Rutman, O.5
Buzdar, A.6
Osterwalder, B.7
-
34
-
-
0029783626
-
Relationship between topoisomerase II levels and resistance to topoisomerase II inhibitors in lung cancer cell lines
-
Houlbrook, S., Harris, A. L., Carmichael, J., and Stratford, I. J. Relationship between topoisomerase II levels and resistance to topoisomerase II inhibitors in lung cancer cell lines. Anticancer Res., 16: 1603-1610, 1996.
-
(1996)
Anticancer Res.
, vol.16
, pp. 1603-1610
-
-
Houlbrook, S.1
Harris, A.L.2
Carmichael, J.3
Stratford, I.J.4
-
35
-
-
0035160615
-
Immunohistochemical expression of topoisomerase IIα (Topo IIα) and multidrug resistance-associated protein (MRP), plus chemosensitivity testing, as chemotherapeutic indices of ovarian and endometrial carcinomas
-
Koshiyama, M., Fujii, H., Kinezaki, M., Morita, Y., Nanno, H., and Yoshida, M. Immunohistochemical expression of topoisomerase IIα (Topo IIα) and multidrug resistance-associated protein (MRP), plus chemosensitivity testing, as chemotherapeutic indices of ovarian and endometrial carcinomas. Anticancer Res., 21: 2925-2932, 2001.
-
(2001)
Anticancer Res.
, vol.21
, pp. 2925-2932
-
-
Koshiyama, M.1
Fujii, H.2
Kinezaki, M.3
Morita, Y.4
Nanno, H.5
Yoshida, M.6
-
36
-
-
0026147704
-
Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells
-
Woessner, R. D., Mattern, M. R., Mirabelli, C. K., Johnson, R. K., and Drake, F. H. Proliferation- and cell cycle-dependent differences in expression of the 170 kilodalton and 180 kilodalton forms of topoisomerase II in NIH-3T3 cells. Cell Growth Differ., 2: 209-214, 1991.
-
(1991)
Cell Growth Differ.
, vol.2
, pp. 209-214
-
-
Woessner, R.D.1
Mattern, M.R.2
Mirabelli, C.K.3
Johnson, R.K.4
Drake, F.H.5
-
37
-
-
0027406440
-
Topoisomerase II α co-amplification with erbB2 in human primary breast cancer and breast cancer cell lines: Relationship to m-AMSA and mitoxantrone sensitivity
-
Smith, K., Houlbrook, S., Greenall, M., Carmichael, J., and Harris, A. L. Topoisomerase II α co-amplification with erbB2 in human primary breast cancer and breast cancer cell lines: relationship to m-AMSA and mitoxantrone sensitivity. Oncogene, 8: 933-938, 1993.
-
(1993)
Oncogene
, vol.8
, pp. 933-938
-
-
Smith, K.1
Houlbrook, S.2
Greenall, M.3
Carmichael, J.4
Harris, A.L.5
-
38
-
-
0029665095
-
Expression of topoisomerase IIα is associated with rapid cell proliferation, aneuploidy, and c-erbB2 overexpression in breast cancer
-
Jarvinen, T. A., Kononen, J., Pelto-Huikko, M., and Isola, J. Expression of topoisomerase IIα is associated with rapid cell proliferation, aneuploidy, and c-erbB2 overexpression in breast cancer. Am. J. Pathol., 148: 2073-2082, 1996.
-
(1996)
Am. J. Pathol.
, vol.148
, pp. 2073-2082
-
-
Jarvinen, T.A.1
Kononen, J.2
Pelto-Huikko, M.3
Isola, J.4
-
39
-
-
0033870292
-
Amplification and deletion of topoisomerase IIα associate with ErbB-2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer
-
Jarvinen, T. A., Tanner, M., Rantanen, V., Barlund, M., Borg, A., Grenman, S., and Isola, J. Amplification and deletion of topoisomerase IIα associate with ErbB- 2 amplification and affect sensitivity to topoisomerase II inhibitor doxorubicin in breast cancer. Am. J. Pathol., 156: 839-847, 2000.
-
(2000)
Am. J. Pathol.
, vol.156
, pp. 839-847
-
-
Jarvinen, T.A.1
Tanner, M.2
Rantanen, V.3
Barlund, M.4
Borg, A.5
Grenman, S.6
Isola, J.7
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