Arg64 β3-adrenoceptor variant and the components of energy expenditure

Obesity Research

Volumn 11, Issue 4, 2003, Pages 509-511

  Walston, Jeremy ^a,c   Andersen, Ross E ^a   Seibert, Michael ^a   Hilfiker, Heather ^a   Beamer, Brock ^a   Blumenthal, Jacob ^a   Poehlman, Eric T ^b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITÉ DE MONTRÉAL   (Canada)

^c JHAAC   (United States)

Author keywords

Energy expenditure; Genetic variation; Gut motility; Resting metabolic rate; Thermic effect of feeding

Indexed keywords

ARGININE; BETA 3 ADRENERGIC RECEPTOR; TRYPTOPHAN;

ADULT; ARTICLE; BASAL METABOLIC RATE; CALORIMETRY; ENERGY METABOLISM; FEMALE; FOOD; GENE FREQUENCY; GENETIC VARIABILITY; GENETICS; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; MALE; OBESITY;

ADULT; ARGININE; BASAL METABOLISM; CALORIMETRY, INDIRECT; ENERGY METABOLISM; FEMALE; FOOD; GENE FREQUENCY; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMANS; MALE; OBESITY; RECEPTORS, ADRENERGIC, BETA-3; TRYPTOPHAN; VARIATION (GENETICS);

EID: 0142248858     PISSN: 10717323     EISSN: None     Source Type: Journal    
DOI: 10.1038/oby.2003.71     Document Type: Article

References (10)

1. Mokdad AH, Serdula MK, Dietz WH, Bowman BA, Marks JS, Koplan JP. The spread of the obesity epidemic in the United States, 1991-1998. JAMA. 1999;282:1519-22.
2. Walston J, Silver K, Bogardus C, et al. Time of onset of non-insulin-dependent diabetes mellitus and genetic variation in the beta 3-adrenergic-receptor gene. N Engl J Med. 1995;333:343-7.
3. Sipilainen R, Uusitupa M, Heikkinen S, Rissanen A, Laakso M. Polymorphism of the beta3-adrenergic receptor gene affects basal metabolic rate in obese Finns. Diabetes. 1997;46:77-80.
4. Widen E, Lehto M, Kanninen T, Walston J, Shuldiner AR, Groop LC. Association of a polymorphism in the beta 3-adrenergic-receptor gene with features of the insulin resistance syndrome in Finns. N Engl J Med. 1995;333:348-51.
5. Ravussin E, Bogardus CA. Brief overview of human energy metabolism and its relationship to essential obesity. Am J Clin Nutr. 1992;55(Suppl 1):242S-5S.
6. Pi-Sunyer FX. Overnutrition and undernutrition as modifiers of metabolic processes in disease states. Am J Clin Nutr. 2000;72(Suppl 2):533S-7S.
7. Folsom AR, Jacobs DR, Jr., Caspersen CJ, Gomez-Marin O, Knudsen J. Test-retest reliability of the Minnesota Leisure Time Physical Activity Questionnaire. J Chronic Dis. 1986;39:505-11.
8. Schoeller DA, van Santen E. Measurement of energy expenditure in humans by doubly labeled water method. J Appl Physiol. 1982;53:955-9.
9. Fletcher DS, Candelore MR, Grujic D, et al. Beta-3 adrenergic receptor agonists cause an increase in gastrointestinal transit time in wild-type mice, but not in mice lacking the beta-3 adrenergic receptor. J Pharmacol Exp Ther. 1998;287:720-4.
10. Bardou M, Dousset B, Deneux-Tharaux C, et al. In vitro inhibition of human colonic motility with SR 59119A and SR 59104A: evidence of a beta3-adrenoceptor-mediated effect. Eur J Pharmacol. 1998;353:281-7.