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Volumn 4, Issue 5, 2003, Pages 468-478

Analysis of known bacterial protein vaccine antigens reveals biased physical properties and amino acid composition

Author keywords

Genome sequence; Vaccine antigens; Vaccine design

Indexed keywords

ADHESIN; ALPHA TOXIN; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; BACTERIAL VACCINE; CATALASE; CITRATE SYNTHASE; COPPER ZINC SUPEROXIDE DISMUTASE; CYTOKINE; CYTOTOXIN; DECORIN; ESCHERICHIA COLI ENTEROTOXIN; FLAGELLIN; HEAT SHOCK PROTEIN; HEAT SHOCK PROTEIN 60; LISTERIOLYSIN; MEMBRANE PROTEIN; PENICILLIN BINDING PROTEIN; PERTACTIN; PERTUSSIS TOXIN; PHOSPHODIESTERASE; PHOSPHOLIPASE D; PNEUMOLYSIN; PORIN; RIBOSOME PROTEIN; SECRETORY PROTEIN; SHIGA TOXIN; TETANUS TOXIN; UNINDEXED DRUG; UREASE;

EID: 0142244175     PISSN: 15316912     EISSN: None     Source Type: Journal    
DOI: 10.1002/cfg.319     Document Type: Article
Times cited : (19)

References (43)
  • 1
    • 0035143948 scopus 로고    scopus 로고
    • Identification and characterization of a novel family of pneumococcal proteins that are protective against sepsis
    • Adamou J, Heinrichs J, Erwin A, et al. 2001. Identification and characterization of a novel family of pneumococcal proteins that are protective against sepsis. Infect Immun 69: 949-958.
    • (2001) Infect. Immun. , vol.69 , pp. 949-958
    • Adamou, J.1    Heinrichs, J.2    Erwin, A.3
  • 2
    • 0033957834 scopus 로고    scopus 로고
    • The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000
    • Bairoch A, Apweiler R. 2000. The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000. Nucleic Acids Res 28: 45-48.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 45-48
    • Bairoch, A.1    Apweiler, R.2
  • 3
    • 85004911383 scopus 로고
    • Positional flexibility of amino acid residues in globular proteins
    • Bhaskaram R, Ponnuswamy P. 1988. Positional flexibility of amino acid residues in globular proteins. Int J Pept Protein Res 32: 242-255.
    • (1988) Int. J. Pept. Protein Res. , vol.32 , pp. 242-255
    • Bhaskaram, R.1    Ponnuswamy, P.2
  • 4
    • 0034925592 scopus 로고    scopus 로고
    • An HLA-directed molecular and bioinformatics approach identifies new HLA-A11 HIV-1 subtype E cytotoxic T lymphocyte epitopes in HIV-1-infected Thais
    • Bond K, Sriwanthana B, Hodge T, et al. 2001. An HLA-directed molecular and bioinformatics approach identifies new HLA-A11 HIV-1 subtype E cytotoxic T lymphocyte epitopes in HIV-1-infected Thais. AIDS Res Human Retroviruses 17: 703-717.
    • (2001) AIDS Res. Human Retroviruses , vol.17 , pp. 703-717
    • Bond, K.1    Sriwanthana, B.2    Hodge, T.3
  • 5
    • 0034568131 scopus 로고    scopus 로고
    • Mining genomes and mapping proteomes: Identification and characterization of protein subunit vaccines
    • Chakravarti D, Fiske M, Fletcher L, Zagursky R. 2000. Mining genomes and mapping proteomes: identification and characterization of protein subunit vaccines. Dev Biol (Basel) 103: 81-90.
    • (2000) Dev. Biol. (Basel) , vol.103 , pp. 81-90
    • Chakravarti, D.1    Fiske, M.2    Fletcher, L.3    Zagursky, R.4
  • 6
    • 0000228203 scopus 로고
    • A model of evolutionary change in proteins
    • Dayhoff M (ed.). National Biomedical Research Foundation: Washington, DC
    • Dayhoff M, Schwartz R, Orcutt B. 1978. A model of evolutionary change in proteins. In Atlas of Protein Sequence and Structure, Dayhoff M (ed.). National Biomedical Research Foundation: Washington, DC: 345-352.
    • (1978) Atlas of Protein Sequence and Structure , pp. 345-352
    • Dayhoff, M.1    Schwartz, R.2    Orcutt, B.3
  • 7
    • 0035859982 scopus 로고    scopus 로고
    • From genome to vaccine: In silica predictions, ex vivo verification
    • De Groot A, Bosma A, Chinai N, et al. 2001. From genome to vaccine: in silica predictions, ex vivo verification. Vaccine 4385-4395.
    • (2001) Vaccine , pp. 4385-4395
    • De Groot, A.1    Bosma, A.2    Chinai, N.3
  • 9
    • 0036459850 scopus 로고    scopus 로고
    • An overview on predicting the subcellular location of a protein
    • Article 0027
    • Feng Z-P. 2002. An overview on predicting the subcellular location of a protein. In Silico Biol 2 [http://www.bioinfo.de/isb/toc_vol_02.htm]. Article 0027.
    • (2002) Silico Biol. , vol.2
    • Feng, Z.-P.1
  • 10
    • 0034059725 scopus 로고    scopus 로고
    • Identification of secreted proteins of Mycobacterium tuberculosis by a bioinformatic approach
    • Gomez M, Johnson S, Gennaro M. 2000. Identification of secreted proteins of Mycobacterium tuberculosis by a bioinformatic approach. Infect Immun 66: 2323-2327.
    • (2000) Infect. Immun. , vol.66 , pp. 2323-2327
    • Gomez, M.1    Johnson, S.2    Gennaro, M.3
  • 11
    • 0036325331 scopus 로고    scopus 로고
    • Antibiotic policies and control of resistance
    • Gould I. 2002. Antibiotic policies and control of resistance. Curr Opin Genet Dev 15: 398-400.
    • (2002) Curr. Opin. Genet. Dev. , vol.15 , pp. 398-400
    • Gould, I.1
  • 12
    • 0035342085 scopus 로고    scopus 로고
    • Antibacterial vaccine design using genomics and proteomics
    • Grandi G. 2001. Antibacterial vaccine design using genomics and proteomics. Trends Biotechnol 19: 181-188.
    • (2001) Trends Biotechnol. , vol.19 , pp. 181-188
    • Grandi, G.1
  • 13
    • 0029746160 scopus 로고    scopus 로고
    • Use of whole genome sequence of Haemophilus influenzae to identify novel virulence genes associated with DNA repeats
    • Hood D. Deadman M, Jennings M, et al. 1996. Use of whole genome sequence of Haemophilus influenzae to identify novel virulence genes associated with DNA repeats. Proc Natl Acad Sci USA 93: 11 121-11 125.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 11121-11125
    • Hood, D.1    Deadman, M.2    Jennings, M.3
  • 14
    • 0034806849 scopus 로고    scopus 로고
    • Genome of the bacterium Streptococcus pneumoniae strain R6
    • Hoskins J, Alborn WJ, Arnold J, et al. 2001. Genome of the bacterium Streptococcus pneumoniae strain R6. J Bacteriol 183: 5709-5717.
    • (2001) J. Bacteriol. , vol.183 , pp. 5709-5717
    • Hoskins, J.1    Alborn, W.J.2    Arnold, J.3
  • 15
    • 0035010116 scopus 로고    scopus 로고
    • Improved pattern for genome-based screening identifies novel cell wall-attached proteins in Gram-positive bacteria
    • Janulczyk R, Rasmussen M. 2001. Improved pattern for genome-based screening identifies novel cell wall-attached proteins in Gram-positive bacteria. Infect Immun 69: 4019-4026.
    • (2001) Infect. Immun. , vol.69 , pp. 4019-4026
    • Janulczyk, R.1    Rasmussen, M.2
  • 16
    • 0034971094 scopus 로고    scopus 로고
    • Pneumococcal virulence factors: Structure and function
    • Jedrzejas M. 2001. Pneumococcal virulence factors: structure and function. Microbiol Mol Biol Rev 65: 187-207.
    • (2001) Microbiol. Mol. Biol. Rev. , vol.65 , pp. 187-207
    • Jedrzejas, M.1
  • 17
    • 0020475449 scopus 로고
    • A simple method for displaying the hydropathic character of a protein
    • Kyte J, Doolittle R. 1982. A simple method for displaying the hydropathic character of a protein. J Mol Biol 157: 105-132.
    • (1982) J. Mol. Biol. , vol.157 , pp. 105-132
    • Kyte, J.1    Doolittle, R.2
  • 18
    • 0032786615 scopus 로고    scopus 로고
    • Immunogenicity of DNA vaccines expressing tuberculosis proteins fused to tissue plasminogen activator signal sequences
    • Li Z, Howard A, Kelley C, Delogu G, Collins F, Morris S. 1999. Immunogenicity of DNA vaccines expressing tuberculosis proteins fused to tissue plasminogen activator signal sequences. Infect Immun 67: 4780-4786.
    • (1999) Infect. Immun. , vol.67 , pp. 4780-4786
    • Li, Z.1    Howard, A.2    Kelley, C.3    Delogu, G.4    Collins, F.5    Morris, S.6
  • 19
    • 0032800247 scopus 로고    scopus 로고
    • Class II MHC quantitative binding motifs derived from a large molecular database with a versatile iterative stepwise discriminant analysis meta-algorithm
    • Mallios R. 1999. Class II MHC quantitative binding motifs derived from a large molecular database with a versatile iterative stepwise discriminant analysis meta-algorithm. Bioinformatics 15: 432-439.
    • (1999) Bioinformatics , vol.15 , pp. 432-439
    • Mallios, R.1
  • 20
    • 0034782871 scopus 로고    scopus 로고
    • Predicting class II MHC/peptide multi-level binding with an iterative stepwise discrimination analysis meta-algorithm
    • Mallios R. 2001. Predicting class II MHC/peptide multi-level binding with an iterative stepwise discrimination analysis meta-algorithm. Bioinformatics 17: 942-948.
    • (2001) Bioinformatics , vol.17 , pp. 942-948
    • Mallios, R.1
  • 21
    • 0002322469 scopus 로고
    • On a test whether one of two random variables is stochastically larger than the other
    • Mann H, Whitney D. 1947. On a test whether one of two random variables is stochastically larger than the other. Ann Moth Statist 18: 50-60.
    • (1947) Ann. Moth. Statist. , vol.18 , pp. 50-60
    • Mann, H.1    Whitney, D.2
  • 22
    • 0034280221 scopus 로고    scopus 로고
    • Tuberculosis vaccine design: Influence of the completed genome sequence
    • Montgomery D. 2000. Tuberculosis vaccine design: influence of the completed genome sequence. Briefings Bioinformat 1: 289-296.
    • (2000) Briefings Bioinformat , vol.1 , pp. 289-296
    • Montgomery, D.1
  • 24
    • 0030614959 scopus 로고    scopus 로고
    • Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites
    • Nielsen H, Engelbrecht J, Brunak S, von Heijne G. 1997. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng 10: 1-6.
    • (1997) Protein Eng. , vol.10 , pp. 1-6
    • Nielsen, H.1    Engelbrecht, J.2    Brunak, S.3    Von Heijne, G.4
  • 25
    • 0036046826 scopus 로고    scopus 로고
    • Bacterial proteomics and vaccine development
    • Nilsson C. 2002. Bacterial proteomics and vaccine development. Am J Pharmacogenom 2: 59-65.
    • (2002) Am. J. Pharmacogenom , vol.2 , pp. 59-65
    • Nilsson, C.1
  • 26
    • 0035055282 scopus 로고    scopus 로고
    • Protection of mice with a tuberculosis subunit vaccine based on a fusion protein of antigen 85B and ESAT-6
    • Olsen A, van Pinxteren L, Okkels L, Rasmussen P, Andersen P. 2001. Protection of mice with a tuberculosis subunit vaccine based on a fusion protein of antigen 85B and ESAT-6. Infect Immun 69: 2773-2778.
    • (2001) Infect. Immun. , vol.69 , pp. 2773-2778
    • Olsen, A.1    Van Pinxteren, L.2    Okkels, L.3    Rasmussen, P.4    Andersen, P.5
  • 27
    • 0029618707 scopus 로고
    • Characterisation of repetitive DNA in the Mycoplasma genitalium genome: Possible role in the generation of antigenic variation
    • Peterson S, Bailey C, Jenson J, et al. 1995. Characterisation of repetitive DNA in the Mycoplasma genitalium genome: possible role in the generation of antigenic variation. Proc Natl Acad Sci USA 92: 11 829-11 833.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11829-11833
    • Peterson, S.1    Bailey, C.2    Jenson, J.3
  • 28
    • 0034629284 scopus 로고    scopus 로고
    • Identification of vaccine candidates against serotype B meningococcus by whole-genome sequencing
    • Pizza M, Scarlato V, Masignani V, et al. 2000. Identification of vaccine candidates against serotype B meningococcus by whole-genome sequencing. Science 287: 1816-1820.
    • (2000) Science , vol.287 , pp. 1816-1820
    • Pizza, M.1    Scarlato, V.2    Masignani, V.3
  • 29
    • 0035888213 scopus 로고    scopus 로고
    • Lessons learned concerning vaccine safety
    • Plotkin S. 2001. Lessons learned concerning vaccine safety. Vaccine 20: S16-S19.
    • (2001) Vaccine , vol.20 , pp. S16-S19
    • Plotkin, S.1
  • 31
    • 0345003936 scopus 로고    scopus 로고
    • Current paradoxes and changing paradigms in vaccinology
    • Poland G. 1999. Current paradoxes and changing paradigms in vaccinology. Vaccine 17: 1605-1611.
    • (1999) Vaccine , vol.17 , pp. 1605-1611
    • Poland, G.1
  • 33
    • 0035925596 scopus 로고    scopus 로고
    • Reverse vaccinology, a genome-based approach to vaccine development
    • Rappuoli R. 2001. Reverse vaccinology, a genome-based approach to vaccine development. Vaccine 19: 2688-2691.
    • (2001) Vaccine , vol.19 , pp. 2688-2691
    • Rappuoli, R.1
  • 34
    • 0035919532 scopus 로고    scopus 로고
    • Identification of vaccine candidate antigens from a genomic analysis of Porphyromonas gingivalis
    • Ross B, Czajkowski L, Hocking D, et al. 2001. Identification of vaccine candidate antigens from a genomic analysis of Porphyromonas gingivalis. Vaccine 19: 4135-4142.
    • (2001) Vaccine , vol.19 , pp. 4135-4142
    • Ross, B.1    Czajkowski, L.2    Hocking, D.3
  • 35
    • 0036094199 scopus 로고    scopus 로고
    • Antibiotic and biocide resistance in bacteria: Introduction
    • Russell A. 2002. Antibiotic and biocide resistance in bacteria: introduction. J Appl Microbiol 92: 1S-3S.
    • (2002) J. Appl. Microbiol. , vol.92 , pp. 1S-3S
    • Russell, A.1
  • 36
    • 0032618626 scopus 로고    scopus 로고
    • Use of BONSAI decision trees for the identification of potential MHC class I peptide epitope motifs
    • Savoie C, Kamikawaji N, Sasazuki T, Kuhara S. 1999. Use of BONSAI decision trees for the identification of potential MHC class I peptide epitope motifs. Pac Symp Biocomput 4: 182-189.
    • (1999) Pac. Symp. Biocomput. , vol.4 , pp. 182-189
    • Savoie, C.1    Kamikawaji, N.2    Sasazuki, T.3    Kuhara, S.4
  • 37
    • 0030219052 scopus 로고    scopus 로고
    • Microbial pathogen genomes - New strategies for identifying therapeutics and vaccine targets
    • Smith D. 1996. Microbial pathogen genomes - new strategies for identifying therapeutics and vaccine targets. Trends Biotechnol 14: 290-293.
    • (1996) Trends Biotechnol. , vol.14 , pp. 290-293
    • Smith, D.1
  • 38
    • 0028966384 scopus 로고
    • Purification and characterisation of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis
    • Sorensen A, Nagai S, Houren G, Anderson P, Anderson A. 1995. Purification and characterisation of a low-molecular-mass T-cell antigen secreted by Mycobacterium tuberculosis. Infect Immun 63: 1710-1717.
    • (1995) Infect. Immun. , vol.63 , pp. 1710-1717
    • Sorensen, A.1    Nagai, S.2    Houren, G.3    Anderson, P.4    Anderson, A.5
  • 39
    • 0032828757 scopus 로고    scopus 로고
    • Diagnosis of cellular states of microbial organisms using proteomics
    • Van Bogelen R, Schiller E, Thomas J, Neidhardt F. 1999. Diagnosis of cellular states of microbial organisms using proteomics. Electrophoresis 20: 2149-2159.
    • (1999) Electrophoresis , vol.20 , pp. 2149-2159
    • Van Bogelen, R.1    Schiller, E.2    Thomas, J.3    Neidhardt, F.4
  • 40
    • 0001884644 scopus 로고
    • Individual comparisons by ranking methods
    • Wilcoxon F. 1945. Individual comparisons by ranking methods. Biometrics 1: 80-83.
    • (1945) Biometrics , vol.1 , pp. 80-83
    • Wilcoxon, F.1
  • 41
    • 0035523169 scopus 로고    scopus 로고
    • Vaccine safety-vaccine benefits: Science and the public's perception
    • Wilson C, Marcuse E. 2001. Vaccine safety-vaccine benefits: science and the public's perception. Nature Rev Immunol 1: 160-165.
    • (2001) Nature Rev. Immunol. , vol.1 , pp. 160-165
    • Wilson, C.1    Marcuse, E.2
  • 42
    • 0035114563 scopus 로고    scopus 로고
    • Use of a whole genome approach to identify vaccine molecules affording protection against Streptococcus pneumoniae infection
    • Wizemann T, Heinrichs J, Adamou J, et al. 2001. Use of a whole genome approach to identify vaccine molecules affording protection against Streptococcus pneumoniae infection. Infect Immun 69: 1593-1598.
    • (2001) Infect. Immun. , vol.69 , pp. 1593-1598
    • Wizemann, T.1    Heinrichs, J.2    Adamou, J.3
  • 43
    • 0014349825 scopus 로고
    • The characterization of amino acid sequences in proteins by statistical methods
    • Zimmermann J, Eliezer N, Simha R. 1968. The characterization of amino acid sequences in proteins by statistical methods. J Theoret Biol 21: 170-201.
    • (1968) J. Theoret. Biol. , vol.21 , pp. 170-201
    • Zimmermann, J.1    Eliezer, N.2    Simha, R.3


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