Association between coronary lesion severity and distal microvascular resistance in patients with coronary artery disease

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 285, Issue 5 54-5, 2003, Pages

  Chamuleau, Steven A J ^a   Siebes, Maria ^a   Meuwissen, Martijn ^a   Koch, Karel T ^a   Spaan, Jos A E ^a   Piek, Jan J ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Blood flow; Blood pressure; Coronary disease; Microcirculation; Physiology

Indexed keywords

ADULT; AGED; ARTICLE; BLOOD FLOW VELOCITY; CLINICAL ARTICLE; CORONARY ARTERY BLOOD FLOW; CORONARY ARTERY DISEASE; CORONARY VASCULAR RESISTANCE; CORRELATION FUNCTION; DISEASE SEVERITY; FEMALE; HUMAN; MALE; MICROVASCULATURE; PRIORITY JOURNAL; TRANSLUMINAL CORONARY ANGIOPLASTY;

EID: 0142232017     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.01021.2002     Document Type: Article

References (23)

1. Austin RE Jr, Aldea GS, Coggins DL, Flynn AE, and Hoffman JI. Profound spatial heterogeneity of coronary reserve. Discordance between patterns of resting and maximal myocardial blood flow. Circ Res 67: 319-331, 1990.
2. Back LH, Kwac EY, and Back MR. Flow rate-pressure drop relation in coronary angioplasty: catheter obstruction effect. J Biomech Eng 118: 83-89, 1996.
3. Chamuleau SAJ, Meuwissen M, Van Eck-Smit BLF, Koch KT, De Jong A, De Winter RJ, Schotborgh CE, Bax M, Verberne HJ, Tijssen JGP, and Piek JJ. Fractional flow reserve, absolute and relative coronary blood flow velocity reserve in relation to the results of technetium-99m sestamibi single photon emission computed tomography in patients with two-vessel coronary artery disease. J Am Coll Cardiol 37: 1316-1322, 2001.
4. Chareonthaitawee P, Kaufmann PA, Rimoldi O, and Camici PG. Heterogeneity of resting and hyperemic myocardial blood flow in healthy humans. Cardiovasc Res 50: 151-161, 2001.
5. Chilian W. Microvascular pressures and resistances in the left ventricular subepicardium and subendocardium. Circ Res 69: 561-570, 1991.
6. Cho YI, Back LH, and Crawford DW. Effect of simulated hyperemia on the flow field in a mildly atherosclerotic coronary artery casting of man. Aviat Space Environ Med 56: 212-219, 1985.
7. De Bruyne B, Hersbach F, Pijls NHJ, Bartunek J, Bech JW, Heyndrickx GR, Gould KL, and Wijns W. Abnormal epicardial coronary resistance in patients with diffuse atherosclerosis but "normal" coronary angiography. Circulation 104: 2401-2406, 2001.
8. Deussen A. Blood flow heterogeneity in the heart. Basic Res Cardiol 93: 430-438, 1998.
9. Doucette JW, Corl PD, Payne HM, Flynn AE, Goto M, Nassi M, and Segal J. Validation of a Doppler guide wire for intravascular measurement of coronary artery flow velocity. Circulation 85: 1899-1911, 1992.
10. Gould KL, Nakagawa Y, Nakagawa K, Sdringola S, Hess MJ, Haynie M, Parker N, Mullani N, and Kirkeeide R. Frequency and clinical implications of fluid dynamically significant diffuse coronary artery disease manifest as graded, longitudinal, base-to-apex myocardial perfusion abnormalities by noninvasive positron emission tomography. Circulation 101: 1931-1939, 2000.
11. Hanley FL, Messina LM, Grattan MT, and Hoffman JIE. The effect of coronary inflow pressure on coronary vascular resistance in the isolated dog heart. Circ Res 54: 760-772, 1984.
12. Kanatsuka H, Lamping K, Eastham C, and Marcus M. Heterogeneous changes in epimyocardial microvascular size during graded coronary stenosis. Evidence of the microvascular site for autoregulation Circ Res 66: 389-396, 1990.
13. Kern MJ, De Bruyne B, and Pijls NH. From research to clinical practice: current role of intracoronary physiologically based decision making in the cardiac catheterization laboratory. J Am Coll Cardiol 30: 613-620, 1997.
14. Meuwissen M, Chamuleau SAJ, Siebes M, Schotborgh CE, Koch KT, De Winter RJ, Bax M, De Jong A, Spaan JAE, and Piek JJ. Role of variability in microvascular resistance on fractional flow reserve and coronary blood flow velocity reserve in intermediate lesions. Circulation 103: 184-187, 2001.
15. Mintz GS, Painter JA, Pichard AD, Kent KM, Satler LF, Popma JJ, Chuang YC, Bucher TA, Sokolowicz LE, and Leon MB. Atherosclerosis in angiographically "normal" coronary artery reference segments: an intravascular ultrasound study with clinical correlations. J Am Coll Cardiol 25: 1479-1485, 1995.
16. Ofili EO, Kern MJ, St Vrain JA, Donohue TJ, Bach R, al-Joundi B, Aguirre FV, Castello R, and Labovitz AJ. Differential characterization of blood flow, velocity, and vascular resistance between proximal and distal normal epicardial human coronary arteries: analysis by intracoronary Doppler spectral flow velocity. Am Heart J 130: 37-46, 1995.
17. Sambuceti G, Marzilli M, Fedele S, Marini C, and L'Abbate A. Paradoxical increase in microvascular resistance during tachycardia downstream from a severe stenosis in patients with coronary artery disease: reversal by angioplasty. Circulation 103: 2352-2360, 2001.
18. Sambuceti G, Marzilli M, Marraccini P, Schneider-Eicke J, Gliozheni E, Parodi O, and L'Abbate A. Coronary vasoconstriction during myocardial ischemia induced by rises in metabolic demand in patients with coronary artery disease. Circulation 95: 2652-2659, 1997.
19. Siegel S, and Castellan Jr, NJ. The Page test for ordered alternatives. In: Nonparametric Statistics for the Behavioral Science (2nd ed.). New York: MacGraw-Hill, 1988, p. 184-189.
20. Spaan JA, Cornelissen AJ, Chan C, Dankelman J, and Yin FC. Dynamics of flow, resistance, and intramural vascular volume in canine coronary circulation. Am J Physiol Heart Circ Physiol 278: H383-H403, 2000.
21. Spaan JAE, Breuls NP, and Laird JD. Diastolic-systolic coronary flow differences are caused by intramyocardial pump action in the anesthetized dog. Circ Res 49: 584-593, 1981.
22. Spaan JAE and Verburg J. Limitation of coronary flow reserve by a stenosis. In: Coronary Blood Flow: Mechanics, Distribution, and Control, edited by Spaan JAE. Dordrecht: Kluwer, 1991, p. 333-361.
23. Van der Zwet PM and Reiber JH. A new approach for the quantification of complex lesion morphology: the gradient field transform; basic principles and validation results. J Am Coll Cardiol 24: 216-224, 1994.