O/W Emulsions compromise the stratum corneum barrier and improve drug penetration

Pharmazie

Volumn 58, Issue 10, 2003, Pages 709-715

  Gloor, M ^a   Hauth, A ^b   Gehring, W ^b  

^a Stadt Karlsruhe gGmbH   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

AQUEOUS CREAM BP 2001; BASE CREAM DAC; CLIOQUINOL; CLIOQUINOL CREAM BP 1999; DODECYL SULFATE SODIUM; GLYCEROL; HYDROCORTISONE; HYDROPHILIC SKIN EMULSION BASE NRF S 25; NONIONIC HYDROPHILIC CREAM DAB 2001; UNCLASSIFIED DRUG; WATER OIL CREAM;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CREAM; DRUG PENETRATION; EMULSION; ERYTHROCYTE; HUMAN; HUMAN EXPERIMENT; LASER DOPPLER FLOWMETRY; NORMAL HUMAN; SKIN PENETRATION; SKIN WATER LOSS; STRATUM CORNEUM;

ADULT; ANTI-INFLAMMATORY AGENTS; EMULSIONS; EXCIPIENTS; HUMANS; HYDROCORTISONE; IRRITANTS; LASER-DOPPLER FLOWMETRY; OILS; OINTMENTS; REGIONAL BLOOD FLOW; SKIN; SKIN ABSORPTION; SODIUM DODECYL SULFATE; SURFACE-ACTIVE AGENTS; WATER; WATER LOSS, INSENSIBLE;

EID: 0142229421     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Schaefer, H.; Redelmeier, Th. E.: Skin barrier-principles of percutaneous absorption, Karger, Basel 1996
2. rd International Symposium on Irritant Contact Dermatitis, p. 292, EDRA, Milan, Italy 2000
3. Imokawa, G.; Akasaki, S.; Minematsu, Y.; Kawai, M.: Arch. Dermatol. Res. 281, 45 (1989)
4. Fartasch, M.: in: Elsner, P.; Maibach, H. I.: Irritant dermatitis. New clinical and experimental aspects. Curr. Probl. Dermatol Derinatol. vol. 23, p. 95 Karger, Basel, 1995
5. Froebe, C. L.; Simion, F. A.; Rhein, L. D.; Cagan, R. H.; Kligman, A.: Dermatologica 181, 277 (1990)
6. Lévêque, J. L.; de Rigal, J.; Saint-Léger, D.; Billy, D.: Skin Pharmacol. 6, 111 (1993)
7. Downing, D. T.; Abraham, W.; Wegner, B. K.; Willmann, K. W.; Marshall, J. L: Arch. Dermatol. Res. 285, 151 (1993)
8. de la Maza, A.; Coderch, L.; López, O.; Baucells, J.; Parra, J. L.: JAOCS 74, 1 (1997)
9. López, O.; Cócera, M.; de la Maza, A.; Coderch, L.; Parra, J. L.: Biochim. Biophys. Acta 1508, 196 (2000)
10. Willis, C. M.; Stephans, C. J. M; Wilkinson, J. D.: J. Invest. Dermatol. 93, 695 (1989)
11. Nakamura, M.; Rikimaru, T.; Yano, T.; Moore, K. G.; Pula, P. J.; Schofield B. H.; Dannenberg, A. M.: J. Invest. Dermatol. 95, 325 (1990)
12. Puttermann G. J.; Wolejsza N. F.; Wolfram M. A.; Laden K.: J. Soc. Cosm. Chem. 28, 521 (1977)
13. White, M. I.; Jenkinson, D.; Lloyd, D. H.: Br. J. Dermatol. 116, 525 (1987)
14. Gloor, M.; Beier, B.: Z. Hautkr. 59, 1657 (1984)
15. Gloor, M.; Haus, G.; Keipert, S.: Skin Pharmacol. Appl. Skin Physiol., 16, 151 (2003)
16. Gabard, B.; Chatelain, E.; Bieli, E.; Haas, St.: Skin Res. Technol. 7, 49 (2001)
17. Piérard, G. E.; Goffin, V.; Piérard-Franchimont, C.: J. Am. Acad. Dermatol. 33, 462 (1995)
18. Bettinger, J.; Gloor, M.; Gehring, W.: Int. J. Cosm. Sci. 16, 53 (1994)
19. Gloor, M.; Gehring, W.: Contact Dermatitis 44, 123 (2001)
20. Bettinger, J.; Fluhr, J.; Gloor, M.; Gehring, W.: Kosm. Med. 1, 46 (1996)
21. Lehmann, L.; Keipert, S; Gloor, M.: Eur. J. Pharm. Biopharm. 52, 129 (2001)
22. Kranz, G.; Schäfer, H.; Zesch, A.: Acta Derm. Venereol. (Stockh) 57, 269 (1977)
23. Imokawa, G.; Abe, A.; Jin, Y.; Higaki, Y.; Kawashima, M.; Hidano, A.: J. Invest. Dermatol. 96, 523 (1991)
24. Yamamoto, A.; Serizawa, S.; Ito, M.; Sato, Y.: Arch. Dermatol. Res. 283, 342 (1991).
25. Rajka, G: Arch. Dermatol. Res. 251, 111 (1974).
26. Triebskom, A.; Gehring, W.; Gloor, M.; Borelli, S.: Z. Hautkr. 66, 145 (1991)
27. Lóden, M.; Olsson, H.; Axéll, T.; Linde, Y. W.: Br. J. Dermatol. 126, 137 (1992)
28. Grunewald, A.; Gloor, M.; Bettinger, J.; Gehring, W.; Kleesz, P.: Dermatosen 43, 69 (1995)
29. Bettinger, J.; Gloor, M.; Peter, C.; Kleesz, P.; Fluhr, J.; Gehring, W.: Dermatology 197, 18 (1998)
30. Fluhr, J. W.; Gloor, M.; Lehmann, L; Lazzerini, S.; Distante, F.; Berardeca, E.: Acta Derm. Venereol. (Stockh) 79, 418 (1999)
31. Rogiers, V.: Skin Pharmacol. Appl. Skin Physiol. 14, 49 (2001)
32. Fullerton, Q.; Fisher, T.; Lahti, A. Q.; Wilhelm, K. T.; Takiwaki, H.; Serup, J.: Contact Dermatitis 35, 1 (1996)
33. Bircher, A.; de Boer E. M.; Agner, T.; Wahlberg, J. E.; Serup, J.: Contact Dermatitis 30, 65 (1994)