N-Glycosylation of 2,3-dideoxyfuranose derivatives having a (diethoxyphosphorothioyl)difluoromethyl group at the 3α-position

Tetrahedron

Volumn 59, Issue 46, 2003, Pages 9059-9073

  Murano, Tetsuo ^a   Yuasa, Yoko ^a   Muroyama, Soichiro ^a   Yokomatsu, Tsutomu ^a   Shibuya, Shiroshi ^a  

^a TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Fluorine; N glycosylations; Neighbouring group effects; Nucleotide analogues; Phosphorus

Indexed keywords

ADENINE NUCLEOTIDE DERIVATIVE; LEWIS ACID; O,O DIETHYL[2 [[TERT BUTYL(DIPHENYL)SILOXY]METHYL] 5 (5 METHYL 2,4 DIOXO 3,4 DIHYDROPYRIMIDIN 1(2H) YL)TETRAHYDROFURAN 3 YL](DIFLUORO)METHYLPHOSPHONOTHIOATE; O,O DIETHYL[2 [[TERT BUTYL(DIPHENYL)SILYL]METHYL] 5 (5 FLUORO 2,4 DIOXO 3,4 DIHYDROPYRIMIDIN 1(2H) YL)TETRAHYDROFURAN 3 YL](DIFLUORO)METHYLPHOSPHONOTHIOATE; PHOSPHATE; PHOSPHOROTHIOIC ACID DERIVATIVE; PYRIMIDINE NUCLEOTIDE; THYMIDINE 3' PHOSPHATE; UNCLASSIFIED DRUG; [[2 (TERT BUTYLDIPHENYLSILANYLOXYMETHYL) 5 (2,4 DIOXO 3,4 DIHYDRO 2H PYRIMIDIN 1 YL)TETRAHYDROFURAN 3 YL]DIFLUOROMETHYL]PHOSPHONOTHIOIC ACID O,O DIETHYL ESTER; [[2 (TERT BUTYLDIPHENYLSILANYLOXYMETHYL) 5 (5 METHYL 2,4 DIOXO 3,4 DIHYDRO 2H PYRIMIDIN 1 YL)TETRAHYDROFURAN 3 YL]DIFLUOROMETHYL]PHOSPHONIC ACID DIETHYL ESTER; [[5 (4 BENZOYLAMINO 2 OXO 2H PYRIMIDIN 1 YL) 2 (TERT BUTYLDIPHENYLSILANYLOXYMETHYL)TETRAHYDROFURAN 3 YL]DIFLUOROMETHYL]PHOSPHONOTHIOIC ACID O,O DIETHYL ESTER;

ARTICLE; CHEMICAL REACTION; DRUG SYNTHESIS; GLYCOSYLATION; OXIDATION; PRIORITY JOURNAL; REACTION ANALYSIS; SILYLATION; STEREOCHEMISTRY;

EID: 0142227252     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2003.09.069     Document Type: Article

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