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Volumn 53, Issue 3, 2003, Pages 223-229

Synthesis and anti-inflammatory activity of some [2-amino-6-(4-substituted aryl)-4-(4-substituted phenyl)-1,6-dihydropyrimidine-5-yl]-acetic acid derivatives

Author keywords

Anti inflammatory activity; Aryl alkanoic acids; Dihydropyrimidines

Indexed keywords

1,6 DIHYDROPYRIMIDINE; ACETIC ACID; ALDEHYDE; DICLOFENAC; GUANIDINE; NITRATE; NONSTEROID ANTIINFLAMMATORY AGENT; PROPIONIC ACID DERIVATIVE; PYRIMIDINE DERIVATIVE; UNCLASSIFIED DRUG;

EID: 0142214788     PISSN: 13300075     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (54)

References (15)
  • 2
    • 0035246513 scopus 로고    scopus 로고
    • Cyclooxygenase inhibitors - Current status and future prospects
    • D. Gred and K. Warner, Cyclooxygenase inhibitors - current status and future prospects, Eur. J. Med. Chem. 36 (2001) 109-126.
    • (2001) Eur. J. Med. Chem. , vol.36 , pp. 109-126
    • Gred, D.1    Warner, K.2
  • 3
    • 0019166162 scopus 로고
    • Current review and comparison of the new nonsteroidal anti-inflammatory agents
    • D. P. Nash, Current review and comparison of the new nonsteroidal anti-inflammatory agents, J. Foot Surg. 19 (1980) 215-217.
    • (1980) J. Foot Surg. , vol.19 , pp. 215-217
    • Nash, D.P.1
  • 4
    • 0019867991 scopus 로고
    • Heteroarylalkanoic acids with potential anti-inflammatory activity. II
    • M. G. Andrisano, M. Di Bella, P. Ferrari, L. Raffa and G. G. Baggio, Heteroarylalkanoic acids with potential anti-inflammatory activity. II, Farmaco 36 (1981) 905-915.
    • (1981) Farmaco , vol.36 , pp. 905-915
    • Andrisano, M.G.1    Di Bella, M.2    Ferrari, P.3    Raffa, L.4    Baggio, G.G.5
  • 6
    • 0035297522 scopus 로고    scopus 로고
    • Aminopyrimidine-carboxyl(ate) interactions in trimethoprim maleate, an antifolate drug
    • P. Prabakaran, J. J. Robert, P. T. Muthiah, G. Bocelli and L. Righi, Aminopyrimidine-carboxyl(ate) interactions in trimethoprim maleate, an antifolate drug, Acta Crystallogr. C. 57 (2001) 459-461.
    • (2001) Acta Crystallogr. C , vol.57 , pp. 459-461
    • Prabakaran, P.1    Robert, J.J.2    Muthiah, P.T.3    Bocelli, G.4    Righi, L.5
  • 7
    • 0036166849 scopus 로고    scopus 로고
    • Synthesis, structure investigations, and antimicrobial activity of selected s-trans-6-aryl-4-isopropyl-2-[2-[(E)-1-phenylalkylidene]-(E)-hydrazino]-1, 4-dihydropyrimidine hydrochlorides
    • E. Gossnitzer, G. Feierl and U. Wagner, Synthesis, structure investigations, and antimicrobial activity of selected s-trans-6-aryl-4-isopropyl-2-[2-[(E)-1-phenylalkylidene]-(E)-hydrazino]-1, 4-dihydropyrimidine hydrochlorides, Eur. J. Pharm. Sci. 15 (2002) 49-61.
    • (2002) Eur. J. Pharm. Sci. , vol.15 , pp. 49-61
    • Gossnitzer, E.1    Feierl, G.2    Wagner, U.3
  • 8
    • 0010275656 scopus 로고
    • Synthesis of functionalized pyrazolo [3,4-d]pyrimidines as potential leishmanicides
    • V. J. Ram and N. Haque, Synthesis of functionalized pyrazolo [3,4-d]pyrimidines as potential leishmanicides, Indian J. Chem. 34B (1995) 521-524.
    • (1995) Indian J. Chem. , vol.34 B , pp. 521-524
    • Ram, V.J.1    Haque, N.2
  • 9
    • 0034922216 scopus 로고    scopus 로고
    • Synthesis and evaluation of anticonvulsant activities of some new arylhexahydropyrimidine-2,4-diones
    • U. Calis and M. Koksal, Synthesis and evaluation of anticonvulsant activities of some new arylhexahydropyrimidine-2,4-diones, Arzneimittelforschung 51 (2001) 523-528.
    • (2001) Arzneimittelforschung , vol.51 , pp. 523-528
    • Calis, U.1    Koksal, M.2
  • 10
    • 0036236866 scopus 로고    scopus 로고
    • A new and efficient synthesis of substituted 6-[(2′ -dialkylamino)ethyl] pyrimidine and 4-N,N-dialkyl-6-vinyl-cytosine derivatives and evaluation of their anti-Rubella activity
    • R. Saladino, U. Ciambecchini, G. Maga, P. Mastromarino, C. Conti and M. Botta, A new and efficient synthesis of substituted 6-[(2′ -dialkylamino)ethyl] pyrimidine and 4-N,N-dialkyl-6-vinyl-cytosine derivatives and evaluation of their anti-Rubella activity, Bioorg. Med. Chem. 10 (2002) 2143-2153.
    • (2002) Bioorg. Med. Chem. , vol.10 , pp. 2143-2153
    • Saladino, R.1    Ciambecchini, U.2    Maga, G.3    Mastromarino, P.4    Conti, C.5    Botta, M.6
  • 11
    • 0028211575 scopus 로고
    • Novel series of TSAO-T derivatives. Synthesis and anti-HIV-1 activity of 4-, 5-, and 6-substituted pyrimidine analogues
    • A. San-Felix, S. Velazquez, M. J. Perez-Perez, J. Balzarini, E. De Clercq and M. J. Camarasa, Novel series of TSAO-T derivatives. Synthesis and anti-HIV-1 activity of 4-, 5-, and 6-substituted pyrimidine analogues, J. Med. Chem. 37 (1994) 453-460.
    • (1994) J. Med. Chem. , vol.37 , pp. 453-460
    • San-Felix, A.1    Velazquez, S.2    Perez-Perez, M.J.3    Balzarini, J.4    De Clercq, E.5    Camarasa, M.J.6
  • 13
    • 0037046581 scopus 로고    scopus 로고
    • Design and synthesis of novel 5-substituted acyclic pyrimidine nucleosides as potent and selective inhibitors of hepatitis B virus
    • R. Kumar, M. Nath and D. L. Tyrrell, Design and synthesis of novel 5-substituted acyclic pyrimidine nucleosides as potent and selective inhibitors of hepatitis B virus, J. Med. Chem. 45 (2002) 2032-2040.
    • (2002) J. Med. Chem. , vol.45 , pp. 2032-2040
    • Kumar, R.1    Nath, M.2    Tyrrell, D.L.3
  • 14
    • 67249094291 scopus 로고
    • Carrageenan induced oedema in the hind paw of the rat as an assay for anti-inflammatory drugs
    • C. A. Winter, E. A. Fisley and G. W. Nuss, Carrageenan induced oedema in the hind paw of the rat as an assay for anti-inflammatory drugs, Proc. Soc. Exp. Biol. Med. 111 (1962) 544-547.
    • (1962) Proc. Soc. Exp. Biol. Med. , vol.111 , pp. 544-547
    • Winter, C.A.1    Fisley, E.A.2    Nuss, G.W.3
  • 15
    • 0027205552 scopus 로고
    • 100 Years of the Biginelli dihydropyrimidine synthesis
    • C. O. Kappe, 100 Years of the Biginelli dihydropyrimidine synthesis, Tetrahedron 49 (1993) 6937-6963.
    • (1993) Tetrahedron , vol.49 , pp. 6937-6963
    • Kappe, C.O.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.