γ-oxo carboxylic acids in heterocyclic synthesis IV. Synthesis of some pyridazines containing phthalyl and tosyl amino acids using DCC as the condensing agent

Phosphorus, Sulfur and Silicon and the Related Elements

Volumn 178, Issue 9, 2003, Pages 1911-1921

  Aly, A A ^a   Wasfy, A A F ^a,b  

^a BENHA UNIVERSITY   (Egypt)

^b BENHA UNIVERSITY   (Egypt)

Author keywords

3(2H) oxo , 3(2H) thioxo or 3 amino pyridazine derivatives; Antibacterial activities; Pyridazine congeners

Indexed keywords

3 AMINO 4 BENZYL 6 (PHENOXATHIIN 2 YL)PYRIDAZINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (DEXTRO ALANYL)AMINOPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (DEXTRO ALANYL)MERCAPTOPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (DEXTRO ALANYL)OXYPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (DEXTRO PHENYLALANYL)AMINOPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (DEXTRO PHENYLALANYL)MERCAPTOPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (DEXTRO PHENYLALANYL)OXYPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (GLYCYL)AMINOPYRIMDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (GLYCYL)MERCAPTOPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (GLYCYL)OXYPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (N PHTHALYL)AMINOPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (N PHTHALYL)MERCAPTOPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (N PHTHALYL)OXYPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (N TOSYLGLYCYL)AMINOPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (N TOSYLGLYCYL)MERCAPTOPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (N TOSYLGLYCYL)OXYPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (VALYL)AMINOPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (VALYL)MERCAPTOPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL) 3 (VALYL)OXYPYRIMIDINE; 4 BENZYL 6 (PHENOXATHIIN 2 YL)PYRIDAZIN 3(2H) ONE; 4 BENZYL 6 (PHENOXATHIIN 2 YL)PYRIDAZIN 3(2H) THIONE; AMINO ACID; ANTIINFECTIVE AGENT; CARBOXYLIC ACID DERIVATIVE; DICYCLOHEXYLCARBODIIMIDE; HETEROCYCLIC COMPOUND; HYDRAZINE; PYRIDAZINE DERIVATIVE; STREPTOMYCIN SULFATE; SULFADIAZINE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG SYNTHESIS; POLYMERIZATION;

EID: 0142200777     PISSN: 10426507     EISSN: None     Source Type: Journal    
DOI: 10.1080/10426500390221096     Document Type: Article

References (18)

1. G. Heinisch and H. Frank, Prog. Med. Chem., 27, 1 (1990).
2. G. Heinisch and H. Kopelent-Frank, Prog. Med. Chem., 29, 141 (1992).
3. E. G. Burns, S. Evans, K. B. Lawrence, and R. C. Vanhanehem, U.S. Pat. 5, 945, 374 (1999); Chem. Abstr., 131, 186364i (1999).
4. H. Deopoortere, PCT. Int. Appl. Wo. Pat. 13, 879 (1999); Chem. Abstr., 130, 247053n (1999).
5. H. R. Wolfe, PCT. Int. Appl. Wo. Pat. 9, 416 (1999); Chem. Abstr., 130, 205105m (1999).
6. R. L. M. Synge, Biochem. J., 39, 363 (1945).
7. S. W. Fox, M. Fling, and N. Bollenback, J. Biol. Chem., 155, 465 (1944).
8. Committee on Medical Research, O.S.R.D., Washington, and the Medical Research Council, London, Science, 102, 627 (1945).
9. T. S. G. Jones, Biochem. J., 42, 111 (1948).
10. A. A. F. Wasfy, M. S. Amine, M. M. H. Arief, and A. A. Aly, Sulfur Letters, 19(2), 45 (1995).
11. A. A. F. Wasfy, Indian J. Chem., 33B, 1098 (1994).
12. E. Lescot, N. P. Buu-Hoi, and D. N. Xuong, J. Chem. Soc., 2408 (1956).
13. C. Lefert, H. Siri Pumchidbouree, S. Hampson, S. Workman, D. Sigee, H. A. S. Epton, and A. Harbour, J. Appl. Bact., 78, 97 (1995).
14. D. A. Kidd and F. E. King, Nature, 162, 776 (1948).
15. R. A. Turner, J. Am. Chem. Soc., 75, 2388 (1955).
16. M. Fling, F. N. Minard, and S. W. Fox, J. Am. Chem. Soc., 69, 2466 (1947).
17. C. S. Bgibson and J. I. Simonson, J. Chem. Soc., 107, 798 (1915).
18. T. S. Harris, J. Biochem., 46, 582 (1950).