Screening the high-yield mutants of gentamicin by 12C ion beam radiation and their productivity in fermentation tank

Chinese Journal of Antibiotics

Volumn 28, Issue 9, 2003, Pages 517-519+554

  Liu, Feng ^a   Fu, Yi ^b   Yan, Hui Can ^b  

^a Institute of Polymer Science   (China)

^b Fuzhou Antibiotic Group Corp   (China)

Author keywords

12C ion beam; Fermentation; Gentamicin; High yield mutant

Indexed keywords

CARBON; GENTAMICIN;

ARTICLE; BACTERIAL STRAIN; BACTERIUM MUTANT; DRUG SYNTHESIS; FERMENTATION TECHNIQUE; NONHUMAN; PRODUCTIVITY; RADIATION; STRAIN DIFFERENCE; TANK;

EID: 0142198381     PISSN: 10018689     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

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2. Taucher-Scholz G, Heilmann J, Kraft G. Induction of DNA strand breaks by heavy ions [J]. Nucl Instrum Methods, 1996,107B:318
3. Xei H M, Wei Z Q, Li W J, et al. Study on the mutation of gentamicin producing strain Micromonospora purpura induced by different energetic heavy ions [J]. Chin J Antibiot, 1998,23(6):462
4. Xie L Q, Zhang Y F, Chen R Y, et al. A study on mutagenic effects of antibiotic-producers by ion implantation [J]. Nucl Tech, 1995,18(6):324