Budd-Chiari syndrome in a patient heterozygous for the point mutation C20221T of the prothrombin gene

Journal of Thrombosis and Haemostasis

Volumn 1, Issue 4, 2003, Pages 852-853

  Balim, Z ^a   Kosova, B ^a   Falzon, K ^b   Bezzina Wettinger, S ^c   Colak, Y ^a  

^a EGE UNIVERSITY   (Turkey)

^b Synergene Technologies Limited   (Malta)

^c UNIVERSITY OF MALTA   (Malta)

Author keywords

[No Author keywords available]

Indexed keywords

PROTHROMBIN;

ADULT; CASE REPORT; GENETICS; HETEROZYGOTE; HUMAN; LETTER; LIVER VEIN THROMBOSIS; MALE; POINT MUTATION;

ADULT; HEPATIC VEIN THROMBOSIS; HETEROZYGOTE; HUMANS; MALE; POINT MUTATION; PROTHROMBIN;

EID: 0142197156     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1046/j.1538-7836.2003.t01-2-00115.x     Document Type: Letter

References (6)

1. Shill M, Henderson JM, Tavill AS. The Budd-Chiari syndrome revisited. The Gastroentrologist 1994; 2: 27-37.
2. Mahmoud AE, Wilde JT, Elias E. Budd-Chiari syndrome and factor V Leiden mutation. Lancet 1995; 345: 526.
3. Bucciarelli P, Franchi F, Alatri A, Bettini P, Moia M. Budd-Chiari syndrome in a patient heterozygous for the G20210A mutation of the prothrombin gene. Thromb Haemost 1998; 79: 445-6.
4. Öner AF, Arslan S, Qaksen H, Ceylan A. Budd-Chiari syndrome in a patient heterozygous for both factor V Leiden and the G20210A mutation on the prothrombin gene. Thromb Haemost 1999; 82: 1366-7.
5. Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3'- untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood 1996; 88: 3698-703.
6. Wylenzek M, Geisen C, Stapenhorst L, Wielckens K, Klinger KR. A novel point mutation in the 3' region of the prothrombin gene at position 20221 in a Lebanese/Syrian family. Thromb Haemost 2001; 85: 943-4.