Chemotherapy and high-dose-rate brachytherapy in the management of advanced cancers of the nasopharynx: Clinical impact of high technology - Is it worth the cost?

Brachytherapy

Volumn 1, Issue 1, 2002, Pages 11-20

  Levendag, Peter C ^a   Nijdam, Wideke M ^a   Van Agthoven, Michel ^b   Uyl De Groot, Carin A ^b  

^a ERASMUS MEDICAL CENTER   (Netherlands)

^b ERASMUS UNIVERSITY ROTTERDAM   (Netherlands)

Author keywords

Brachytherapy; Chemotherapy; Costs; Nasopharynx; Stereotaxy

Indexed keywords

CISPLATIN; FLUOROURACIL;

ACCURACY; ARTICLE; BEAM THERAPY; CANCER ADJUVANT THERAPY; CANCER STAGING; CANCER SURVIVAL; COST BENEFIT ANALYSIS; DISEASE SEVERITY; EXTERNAL BEAM RADIOTHERAPY; HEALTH CARE COST; HOSPITAL COST; HUMAN; LARYNX CARCINOMA; MOUTH CARCINOMA; MULTIMODALITY CANCER THERAPY; NASOPHARYNX CARCINOMA; OROPHARYNX CARCINOMA; PRIORITY JOURNAL; RADIATION DOSE; RADIOISOTOPE THERAPY; STEREOTACTIC RADIOTHERAPY; SURVIVAL RATE; TECHNOLOGY; TREATMENT OUTCOME;

BRACHYTHERAPY; COMBINED MODALITY THERAPY; COSTS AND COST ANALYSIS; HUMANS; NASOPHARYNGEAL NEOPLASMS; NEOPLASM STAGING; RADIOTHERAPY DOSAGE; TIME FACTORS;

EID: 0142196603     PISSN: 15384721     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1538-4721(02)00005-3     Document Type: Article

References (40)

1. Teo P.M.L., Leung S.F., Lee W.Y.et al. Intracavitary brachytherapy significantly enhances local control of early T-stage nasopharyngeal carcinoma. The existence of a dose-tumor control relationship above conventional tumoricidal dose Int J Radiat Oncol Biol Phys. 46:2000;445-458.
2. Syed A.M., Puthawala A.A., Damore S.J.et al. Brachytherapy for primary and recurrent nasopharyngeal carcinoma. 20 years' experience at Long Beach Memorial Int J Radiat Oncol Biol Phys. 47:2000;1311-1321.
3. Perez C.A., Devineni V.R., Marcial-Vega V.et al. Carcinoma of the nasopharynx. Factors affecting prognosis Int J Radiat Oncol Biol Phys. 22:1992;941-947.
4. Wang C.C. Improved local control of nasopharyngeal carcinoma after intracavitary brachytherapy boost. Am J Clin Oncol. 14:1991;5-8.
5. Bedwinik J.M., Perez C.A., Keys D.J. Analysis of failure after definitive irradiation for epidermoid carcinoma of the nasopharynx. Cancer. 45:1990;2725-2729.
6. Vikram B., Mishra U.B., Strong E.W.et al. Patterns of failure in carcinoma of the nasopharynx. Int J Radiat Oncol Biol Phys. 11:1985;1455-1459.
7. Mesic J.B., Fletcher G.H., Goepfert H. Megavoltage irradiation of epithelial tumors of the nasopharynx. Int J Radiat Oncol Biol Phys. 7:1981;447-453.
8. Lee A.W.M., Chan D.K.K., Fowler J.F. l. Effect of time, dose and fractionation on local control of nasopharyngeal carcinoma. Radiother Oncol. 36:1995;24-31.
9. Kwong D.L.W., Sham J.S.T., Choy D. The effect of loco-regional control on distant metastatic dissemination in carcinoma of the nasopharynx. An analysis of 1301 patients Int J Radiat Oncol Biol Phys. 30:1994;1029-1036.
10. Lee A.W., Poon Y.F., Foo W.et al. Retrospective analysis of 5037 patients with nasopharyngeal carcinoma treated during 1976-1985. Overall survival and patterns of failure Int J Radiat Oncol Biol Phys. 23:1992;261-270.
11. Chang J.T., See L.C., Tang S.G.et al. The role of brachytherapy in early-stage nasopharyngeal carcinoma. Int J Radiat Oncol Biol Phys. 36:1996;1019-1024.
12. Lagerwaard F.J., Levendag P.C., van Nimwegen A.et al. High precision boosting of the nasopharynx. Dosimetric comparison of conventional and conformal radiotherapy techniques J HK Coll Radiol. 4:2001;120-125.
13. Mitsuhashi N., Sakurai H., Katano S.et al. Stereotactic radiotherapy for locally recurrent nasopharyngeal carcinoma. Laryngoscope. 109:1999;805-809.
14. Hunt M.A., Zelefsky M.J., Wolden S.et al. Treatment planning and delivery of intensity-modulated radiation therapy for primary nasopharynx cancer. Int J Radiat Oncol Biol Phys. 49:2001;623-632.
15. Levendag P.C., Peters R., Meeuwis C.A.et al. A new applicator design for endocavitary brachytherapy of cancer in the nasopharynx. Radiother Oncol. 45:1997;95-98.
16. Levendag P.C., Schmitz P.I.M., Jansen P.P.et al. Fractionated high-dose-rate brachytherapy in primary carcinoma of the nasopharynx. J Clin Oncol. 16:1998;2213-2220.
17. Al-Sarraf M., Pajak T.F., Cooper J.S.et al. Chemo-radiotherapy in patients with locally advanced nasopharyngeal carcinoma. A Radiation Therapy Oncology Group study. J Clin Oncol. 8:1990;1342-1351.
18. Al-Sarraf M., LeBlanc M., Shanker Giri P.G.et al. Chemoradiotherapy versus radiotherapy in patients with advanced nasopharyngeal cancer. Phase III randomized Intergroup study 0099. J Clin Oncol. 16:1998;1310-1317.
19. Cheng S.H., Jian J.J.M., Tsai S.Y.et al. Long-term survival of nasopharyngeal carcinoma following concomitant radiotherapy and chemotherapy. Int J Radiat Oncol Biol Phys. 48:2000;1323-1330.
20. Cooper J.S., Lee H., Torrey M.et al. Improved outcome secondary to concurrent chemoradiotherapy for advanced carcinoma of the nasopharynx. Preliminary corroboration of the Intergroup experience Int J Radiat Oncol Biol Phys. 47:2000;861-866.
21. Munro A.J. An overview of randomized controlled trials of adjuvant chemotherapy in head and neck cancer. Br J Cancer. 72:1995;83-91.
22. Chan A.T.C., Teo P.M.L., Leung T.W.T.et al. The role of chemotherapy in the management of nasopharyngeal carcinoma. Cancer. 82(6):1998;1003-1012.
23. Preliminary results of a randomized trial comparing neoadjuvant chemotherapy (cisplatin, epirubicin, bleomycin) plus radiotherapy vs. radiotherapy alone in stage IV (> or = N2, M0) undifferentiated nasopharyngeal carcinoma: a positive effect on progression-free survival. International Nasopharynx Cancer Study Group. VUMCA I trial. Int J Radiat Oncol Biol Phys 1996;35:463-469.
24. Pignon J.P., Bourhis J. Meta-analysis of chemotherapy in head and neck cancer. Br J Cancer. 72:1995;1062-1063.
25. El-Sayed S., Nelson N. Adjuvant and adjunctive chemotherapy in the management of squamous cell carcinoma of the head and neck region. J Clin Oncol. 14:1996;838-847.
26. Eisbruch A., Ten Haken R.K., Kim H.M.et al. Dose, volume, and function relationships in parotid salivary glands following conformal and intensity-modulated irradiation of head and neck cancer. Int J Radiat Oncol Biol Phys. 45:1999;577-587.
27. Nowak P.J.C.M., Wijers O.B., Lagerwaard F.J.et al. A three-dimensional CT-based target definition for elective irradiation of the neck. Int J Radiat Oncol Biol Phys. 45:1999;33-39.
28. Wijers O.B., Levendag P.C., Tan T.et al. A simplified CT-based definition of the lymph node levels in the node negative neck. Radiother Oncol. 52:1999;35-42.
29. Levendag PC, Lagerwaard FJ, Pan de C, et al. High-dose, high-precision treatment options for boosting cancer of the nasopharynx. Radiother Oncol. In press.
30. Levendag P.C., Lagerwaard F.J., Noever I.et al. The role of endocavitary brachytherapy with or without chemotherapy in cancer of the nasopharynx. Int J Radiat Oncol Biol Phys. 52:2002;755-768.
31. Orecchia R., Redda M.G., Ragona R.et al. Results of hypofractionated stereotactic re-irradiation on 13 locally recurrent nasopharyngeal carcinomas. Radiother Oncol. 53:1999;23-28.
32. Levendag P.C., Lagerwaard F.J., Pan de C.et al. IMRT, stereotactic radiotherapy or brachytherapy following external beam radiotherapy. Target coverage and sparing in early Stage NPC. Presented at ASTRO, Boston, Massachusetts, October 22-26, 2000 Int J Radiat Oncol Biol Phys. 48:2000;323-324.
33. Allen P.W. Surgical pathology (Chapt. 5). Hasselt C.A., Gibb A.G. Nasopharyngeal carcinoma. 2nd ed:; 1999;69-104 The Chinese University Press, Hong Kong.
34. Sanguinetti G., Corvo R. Treatment of nasopharyngeal carcinoma. State of the art and new perspectives Oncol Rep. 6:1999;377-391. [Review].
35. Sobin L.H., Wittekind C.H. Nasopharynx. American Joint Committee on Cancer Manual for staging of cancer. 5th ed:; 1997;27-30 Lippincott, Philadelphia.
36. Drummond M., O'Brien B., Stoddart G.et al. Methods for the economic evaluation of health care programmes (Chapt. 4). ; 1997;Oxford University Press, Oxford. p. 52-88.
37. van Agthoven M., van Ineveld B.M., de Boer M.F.et al. The costs of head and neck oncology. Primary tumours, recurrent tumours and long-term follow-up Eur J Cancer. 37(17):2001;2204-2211.
38. Gold M., Siegel J., Russell L.et al. Cost-effectiveness in health and medicine (Chapt. 6). ; 1996;Oxford University Press, New York. p. 176-213.
39. Kuy vd A. Pharmacotherapeutical compass 1998. ; 1998;Dutch Health Care Board, Amstelveen, The Netherlands.
40. Wolden S.L., Zelefsky M.J., Kraus D.H.et al. Accelerated concomitant boost radiotherapy and chemotherapy for advanced nasopharyngeal carcinoma. J Clin Oncol. 19:2001;1105-1110.