Synthesis and biological evaluation of S-acyl-3-thiopropyl prodrugs of N-phosphonoacetyl-L-aspartate (PALA)

European Journal of Medicinal Chemistry

Volumn 38, Issue 10, 2003, Pages 883-891

  Gagnard, Valérie ^a   Leydet, Alain ^a   Le Mellay, Véronique ^a   Aubenque, Marielle ^a   Morère, Alain ^a   Montero, Jean Louis ^a  

^a UNIV MONTPELLIER   (France)

Author keywords

Calculated log P; Lung carcinoma; PALA; Prodrugs; S acyl 3 thiopropyl

Indexed keywords

BIS(2 METHOXYETHYL) O,O BIS(PIVALOYL 3 THIOPROPYL) N PHOSPHONOACETYLASPARTIC ACID; BIS[2 (2 METHOXYETHOXY)ETHYL] O,O BIS(ACETYL 3 THIOPROPYL) N PHOSPHONOACETYLASPARTIC ACID; BIS[2 (2 METHOXYETHOXY)ETHYL] O,O BIS(PIVALOYL 3 THIOPROPYL) N PHOSPHONOACETYLASPARTIC ACID; BIS[2 [2 (2 METHOXYETHOXY)ETHOXY]ETHYL] O,O BIS(ACETYL 3 THIOPROPYL) N PHOSPHONOACETYLASPARTIC ACID; PHOSPHONIC ACID DERIVATIVE; PRODRUG; PROPANE; S ACYL 3 THIOPROPYL; SPARFOSIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CANCER CELL CULTURE; CYTOTOXICITY; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; EVALUATION; LUNG CARCINOMA;

EID: 0142188559     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejmech.2003.07.002     Document Type: Article

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