A novel methylthio metabolite of s-triazolo[3,4-a]phthalazine, a lead compound for the development of antianxiety drugs, in rats

Life Sciences

Volumn 74, Issue 1, 2003, Pages 29-36

  Imamura, Yorishige ^a   Noda, Atsuko ^b   Imamura, Takafumi ^b   Ono, Yoko ^b   Okawara, Tadashi ^a   Noda, Hiroshi ^c  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Lipophilic metabolite; Methylthio conjugate; Rat hepatocytes; Rat urine; s Triazolo 3,4 a phthalazine

Indexed keywords

ANXIOLYTIC AGENT; TRIAZOLO[3,4 A]PHTHALAZINE DERIVATIVE;

ARTICLE; CELL ISOLATION; CONJUGATION; CONTROLLED STUDY; INTESTINE FLORA; LIPOPHILICITY; LIVER CELL; MALE; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RAT;

EID: 0142186315     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2003.06.032     Document Type: Article

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