Primary human herpesvirus-6 and -7 infections, often coinciding, misdiagnosed as measles in children from a tropical region of Brazil

Epidemiology and Infection

Volumn 131, Issue 2, 2003, Pages 873-879

  Oliveira, S A ^a   Turner, D J ^b,f   Knowles, W ^c   Nascimento, J P ^d   Brown, D W G ^c   Ward, K N ^e  

^a Discip Doencas Infecc Parasitarias   (Brazil)

^b IMPERIAL COLLEGE SCHOOL OF MEDICINE   (United Kingdom)

^c PUBLIC HEALTH ENGLAND   (United Kingdom)

^d INSTITUTO OSWALDO CRUZ   (Brazil)

^e ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^f IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G ANTIBODY;

ADOLESCENT; ANTIBODY DETECTION; ARTICLE; BLOOD SAMPLING; BRAZIL; CHILD; CHILD CARE; CONTROLLED STUDY; DIAGNOSTIC ERROR; ERYTHEMA INFECTIOSUM; GEOGRAPHY; HERPES VIRUS INFECTION; HUMAN; HUMAN HERPESVIRUS 6; HUMAN HERPESVIRUS 7; IMMUNOFLUORESCENCE; INFANT; MAJOR CLINICAL STUDY; MEASLES; RASH; RUBELLA; SOCIOECONOMICS; TROPICS;

ADOLESCENT; ANTIBODIES, VIRAL; BRAZIL; CHILD; CHILD, PRESCHOOL; DIAGNOSIS, DIFFERENTIAL; DIAGNOSTIC ERRORS; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HERPESVIRIDAE INFECTIONS; HERPESVIRUS 6, HUMAN; HERPESVIRUS 7, HUMAN; HUMANS; INFANT; MALE; MEASLES;

EID: 0142180026     PISSN: 09502688     EISSN: None     Source Type: Journal    
DOI: 10.1017/S0950268803008823     Document Type: Article

References (25)

1. Juretić M. Exanthema subitum: a review of 243 cases. Helvetica Paediatrica Acta 1963; 1: 80-95.
2. Yamanishi K, Okuno T, Shiraki K, et al. Identification of human herpesvirus-6 as a causal agent for exanthem subitum. Lancet 1988; i: 1065-1067.
3. Tait DR, Ward KN, Brown DWG, Miller E. Exanthem subitum (roseola infantum) misdiagnosed as measles or rubella. BMJ 1996; 312: 101-102, 226.
4. Tanaka K, Kondo T, Torigoe S, Okada S, Mukai T, Yamanishi K. Human herpesvirus-7: another causal agent for roseola (exanthem subitum). J Pediatr 1994; 125: 1-5.
5. Ward KN, Turner DJ, Couto Parada X, Thiruchelvam AD. Use of IgG antibody avidity for differentiation of primary human herpesvirus-6 and -7 infections. J Clin Microbiol 2001; 39: 959-963.
6. Brasil, Ministério da Saúde. Fundação Nacional de Saúde. Capacitação de pessoal para vigilância epidemiológica do sarampo. Módulo Instrucional I, Brasilia 1992: 1-77.
7. Hummel KB, Erdman DD, Heath J, Bellini WJ. Baculovirus expression of the nucleoprotein gene of measles virus and utility of the recombinant protein in diagnostic enzyme immunoassays. J Clin Microbiol 1992; 30: 2874-2880.
8. Cubel RCN, Alferes ACR, Cohen BJ, Nascimento JP. Application to immunoglobulin M capture hemadherence assays of hemagglutination of monkey erythrocytes by native and recombinant human parvovirus B19 antigen. J Clin Microbiol 1994; 32: 1997-1999.
9. Gunasegaran K, Lim TW, Ahmed A, Aaskov JG, Lam SK, Pang T. Hemadsorption immunosorbent technique for the detection of dengue immunoglobulin M antibody. J Clin Microbiol 1986; 23: 170-174.
10. Ward KN, Gray JJ, Efstathiou S. Brief report: primary human herpesvirus-6 infection in a patient following liver transplantation from a seropositive donor. J Med Virol 1989; 28: 69-72.
11. Ward KN, Couto Parada X, Passas J, Thiruchelvam AD. Evaluation of specificity and sensitivity of indirect immunofluorescence tests for IgG to human herpesviruses-6 and -7. J Virol Methods 2002; 106: 107-113.
12. Ward KN, Gray JJ, Fotheringham MW, Sheldon MJ. IgG antibodies to human herpesvirus-6 in young children: changes in avidity of antibody correlate with time after infection. J Med Virol 1993; 39: 131-138.
13. Caserta MT, Breese Hall C, Schnabel K, Long CE, D'Heron N. Primary human herpesvirus 7 infection: a comparison of human herpesvirus 7 and human herpesvirus 6 infections in children. J Paediatr 1998; 133: 386-389.
14. Katsafanas GC, Schirmer EC, Wyatt LS, Frenkel N. In vitro activation of human herpesviruses 6 and 7 from latency. Proc Natl Acad Sci USA 1996; 93: 9788-9792.
15. Torigoe S, Kumamoto T, Koide W, Taya K, Yamanishi K. Clinical manifestations associated with human herpesvirus 7 infection. Arch Dis Child 1995; 72: 518-519.
16. Eisen HN, Siskind GW. Variations in affinities of antibodies during the immune response. Biochemistry 1964; 3: 996-1008.
17. Hedman K, Lappalainen M, Söderland M, Hedman L. Avidity of IgG in serodiagnosis of infectious diseases. Rev Med Microbiol 1993; 4: 123-129.
18. Goldblatt D. Simple solid phase assays of avidity. In: Johnstone A, Turner MW, eds. Immunochemistry 2: a practical approach. Oxford: IRL Press at Oxford University Press, 1997: 31-51.
19. Inouye S, Hasegawa A, Matsuno S, Katow S. Changes in antibody avidity after virus infections: detection by an immunosorbent assay in which a mild protein-denaturing agent is employed. J Clin Microbiol 1984; 20: 525-529.
20. Pullen GR, Fitzgerald MG, Hosking CS. Antibody avidity determination by ELISA using thiocyanate elution. J Immunol Meth 1986; 106: 119-125.
21. Oliveira SA, Siqueira MM, Camacho LAB, et al. The aetiology of maculopapular rash diseases in Niterói, State of Rio de Janeiro, Brazil: implications for measles surveillance. Epidemiol Infect 2001 ; 127: 509-516.
22. Black JB, Durigon E, Kite-Powell K, et al. Seroconversion to human herpesvirus 6 and human herpesvirus 7 among Brazilian children with clinical diagnoses of measles or rubella. Clin Infect Dis 1996; 23: 1156-1158.
23. Black JB, Schwarz TF, Patton JL, et al. Evaluation of immunoassays for detection of antibodies to human herpesvirus 7. Clin Diagn Lab Immunol 1996; 3: 79-83.
24. Huang LM, Lee CY, Liu MY, Lee PI. Primary infections of human herpesvirus-7 and herpesvirus-6: a comparative, longitudinal study up to 6 years of age. Acta Paediatr 1997; 86: 604-608.
25. Ward KN, Kalima P, MacLeod KM, Riordan T. Neuroinvasion during delayed primary HHV-7 infection in an immunocompetent adult with encephalitis and flaccid paralysis. J Med Virol 2002; 67: 538-541.