A possible molecular mechanism of hanatoxin binding-modified gating in voltage-gated K+-channels

Journal of Molecular Recognition

Volumn 16, Issue 6, 2003, Pages 392-395

  Lou, Kuo Long ^a,f   Huang, Po Tsang ^a   Shiau, Yu Shuan ^b,c   Liaw, Yen Chywan ^d   Shiau, Yuh Yuan ^b,c   Liou, Horng Huei ^e  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^d INSTITUTE OF MOLECULAR BIOLOGY   (Taiwan)

^e NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^f NTUMC   (Taiwan)

Author keywords

Docking; drk1; Hanatoxin; Inhibition of channel gating; Molecular simulation; S3 S4 linker; S3C; Shaker; Spatial freedom

Indexed keywords

DELAYED RECTIFIER POTASSIUM CHANNEL; HANATOXIN; PEPTIDE; POTASSIUM CHANNEL; PROTEIN SUBUNIT; SHAKER POTASSIUM CHANNEL; VOLTAGE GATED POTASSIUM CHANNEL;

ARTICLE; BINDING SITE; CHANNEL GATING; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; HISTORY; METABOLISM; PROTEIN BINDING; PROTEIN CONFORMATION;

BINDING SITES; COMPUTER SIMULATION; DELAYED RECTIFIER POTASSIUM CHANNELS; HISTORY, EARLY MODERN 1451-1600; ION CHANNEL GATING; MODELS, MOLECULAR; PEPTIDES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SUBUNITS; SHAKER SUPERFAMILY OF POTASSIUM CHANNELS;

EID: 0142177158     PISSN: 09523499     EISSN: None     Source Type: Journal    
DOI: 10.1002/jmr.614     Document Type: Article

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