Fine Structural Localization of Connexin-36 Immunoreactivity in Mouse Cerebral Cortex and Thalamus

Journal of Comparative Neurology

Volumn 466, Issue 4, 2003, Pages 457-467

  Liu, Xiao Bo ^a   Jones, Edward G ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Gap junctions; Reticular nucleus; Somatosensory; Ventral posterior nucleus

Indexed keywords

CONNEXIN 36;

ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; CELL MEMBRANE; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; ELECTRICITY; FOREBRAIN; GAP JUNCTION; IMMUNOCYTOCHEMISTRY; IMMUNOELECTRON MICROSCOPY; IMMUNOGOLD LABELING; IMMUNOREACTIVITY; LATERAL RETICULAR NUCLEUS; MOUSE; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN STRUCTURE; SOMATOSENSORY SYSTEM; THALAMUS;

ANIMALS; CEREBRAL CORTEX; CONNEXINS; GAP JUNCTIONS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED ICR; MICROSCOPY, IMMUNOELECTRON; NEURAL PATHWAYS; NEURONS; THALAMUS;

EID: 0142169935     PISSN: 00219967     EISSN: None     Source Type: Journal    
DOI: 10.1002/cne.10901     Document Type: Article

References (46)

1. Amadeo A, Ortino B, Frassoni C. 2001. Parvalbumin and GABA in the developing somatosensory thalamus of the rat: an immunocytochemical ultrastructural correlation. Anat Embryol 203:109-119.
2. Arcuino G, Lin JH, Takano T, Liu C, Jiang L, Gao Q, Kang J, Nedergaard M. 2002. Intercellular calcium signaling mediated by point-source burst release of ATP. Proc Natl Acad Sci USA 99:9840-9845.
3. Bal T, McCormick DA. 1993. Mechanisms of oscillatory activity in guinea-pig nucleus reticularis thalami in vitro: a mammalian pacemaker. J Physiol 468:669-691.
4. Belluardo N, Giuseppa M, Trovato-Salinaro A, Le Gurun S, Charollais A, Serre-Beinier V, Amato G, Haefliger JA, Meda P, Condorelli DF. 2000. Expression of connexin36 in the adult and developing rat brain. Brain Res 865:121-138.
5. Bennett MV. 2000. Electrical synapses, a personal perspective (or history). Brain Res Rev 32:16-28.
6. Bennett MVL. 1997. Gap junctions as electrical synapses. J Neurocytol 26:349-366.
7. 2+/calmodulin protein kinase gene expression in the rat central nervous system. Neuroscience 46:825-849.
8. Bittman KS, LoTurco JJ. 1999. Differential regulation of connexin 26 and 43 in murine neocortical precursors. Cereb Cortex 9:188-195.
9. + fluxes in intact cells. FASEB J 15:10-12.
10. Condorelli DF, Parenti R, Spinella F, Trovato SA, Belluardo N, Cardile V, Cicirata F. 1998. Cloning of a new gap junction gene (Cx36) highly expressed in mammalian brain neurons. Eur J Neurosci 10:1202-1208.
11. Connors BW, Benardo LS, Prince DA. 1983. Coupling between neurons of the developing rat neocortex. J Neurosci 3:773-782.
12. Cotrina ML, Lin JH, Alves-Rodrigues A, Liu S, Li J, Azmi-Ghadimi H, Kang J, Naus CC, Nedergaard M. 1998. Connexins regulate calcium signaling by controlling ATP release. Proc Natl Acad Sci USA 95:15735-15740.
13. Deans MR, Gibson JR, Sellitto C, Connors BW, Paul DL. 2001. Synchronous activity of inhibitory networks in neocortex requires electrical synapses containing connexin36. Neuron 31:477-485.
14. Galarreta M, Hestrin S. 1999. A network of fast-spiking cells in the neocortex connected by electrical synapses. Nature 402:72-75.
15. Galarreta M, Hestrin S. 2002. Electrical and chemical synapses among parvalbumin fast-spiking GABAergic interneurons in adult mouse neocortex. Proc Natl Acad Sci USA 99:12438-12443.
16. Gibson JR, Beierlein M, Connors BW. 1999. Two networks of electrically coupled inhibitory neurons in neocortex. Nature 402:75-79.
17. Hendry SH, Jones EG, Emson PC, Lawson DE, Heizmann CW, Streit P. 1989. Two classes of cortical GABA neurons defined by differential calcium binding protein immunoreactivities. Exp Brain Res 76:467-472.
18. Hormuzdi SG, Pais I, LeBeau FE, Towers SK, Rozov A, Buhl EH, Whittington MA, Monyer H. 2001. Impaired electrical signaling disrupts gamma frequency oscillations in connexin 36-deficient mice. Neuron 31:487-495.
19. Houser CR, Vaughn JE, Barber RP, Roberts E. 1980. GABA neurons are the major cell type of the nucleus reticularis thalami. Brain Res 200:341-354.
20. Huang RP, Fan Y, Hossain MZ, Peng A, Zeng ZL, Boynton AL. 1998. Reversion of the neoplastic phenotype of human glioblastoma cells by connexin 43 (cx43). Cancer Res 58:5089-5096.
21. Hughes SW, Blethyn KL, Cope DW, Crunelli V. 2002. Properties and origin of spikelets in thalamocortical neurones in vitro. Neuroscience 110:395-401.
22. Jones EG, Liu XB. 2002. Cellular and subcellular expression of connexin-36 in mouse cerebral cortex and thalamus during postnatal development. Soc Neurosci Abstr 28:731.15.
23. Kawaguchi Y, Kubota Y. 1993. Correlation of physiological subgroupings of nonpyramidal cells with parvalbumin- and calbindinD28k-immunoreactive neurons in layer V of rat frontal cortex. J Neurophysiol 70:387-396.
24. Landisman CE, Long MA, Beierlein M, Deans MR, Paul DL, Connors BW. 2002. Electrical synapses in the thalamic reticular nucleus. J Neurosci 22:1002-1009.
25. Lin JH, Yang J, Liu S, Takano T, Wang X, Gao Q, Willecke K, Nedergaard M. 2003. Connexin mediates gap junction-independent resistance to cellular injury. J Neurosci 23:430-441.
26. Liu XB, Warren RA, Jones EG. 1995. Synaptic distribution of afferents from reticular nucleus in ventroposterior nucleus of cat thalamus. J Comp Neurol 352:187-202.
27. Liu XB, Munoz A, Jones EG. 1998. Changes in subcellular localization of metabotropic glutamate receptor subtypes during postnatal development of mouse thalamus. J Comp Neurol 395:450-465.
28. Liu XB, Bolea S, Golshani P, Jones EG. 2001. Differentiation of corticothalamic and thalamocortical synapses on mouse reticular nucleus neurons by EPSC amplitude and AMPA receptor subunit composition. Thalamus Rel Syst 1:15-29.
29. MacVicar BA, Dudek FE. 1981. Electrotonic coupling between pyramidal cells: a direct demonstration in rat hippocampal slices. Science 213:782-785.
30. Meier C, Petrasch-Parwez E, Habbes H-W, Teubner B, Guldenagel M, Degen J, Sohl G, Willecke K, Dermietzel R. 2002. Immunohistochemical detection of the neuronal connexin36 in the mouse central nervous system in comparison to connexin36-deficient tissues. Histochem Cell Biol 117:461-471.
31. O'Brien J, al Ubaidi MR, Ripps H. 1996. Connexin 35: a gap-junctional protein expressed preferentially in the skate retina. Mol Biol Cell 7:233-243.
32. O'Brien J, Bruzzone R, White TW, al Ubaidi MR, Ripps H. 1998. Cloning and expression of two related connexins from the perch retina define a distinct subgroup of the connexin family. J Neurosci 18:7625-7637.
33. Omori Y, Yamasaki H. 1998. Mutated connexin43 proteins inhibit rat glioma cell growth suppression mediated by wild-type connexin43 in a dominant-negative manner. Int J Cancer 78:446-453.
34. Peinado A, Yuste R, Katz LC. 1993. Extensive dye coupling between rat neocortical neurons during the period of circuit formation. Neuron 10:103-114.
35. Peters A, Palay SL, Webster HD. 1991. The fine structure of the nervous system. New York: Oxford University Press.
36. Qin H, Shao Q, Curtis H, Galipeau J, Belliveau DJ, Wang T, Alaoui-Jamali MA, Laird DW. 2002. Retroviral delivery of connexin genes to human breast tumor cells inhibits in vivo tumor growth by a mechanism that is independent of significant gap junctional intercellular communication. J Biol Chem 277:29132-29138.
37. Rash JE, Staines WA, Yasumura T, Patel D, Furman CS, Stelmack GL, Nagy JI. 2000. Immunogold evidence that neuronal gap junctions in adult rat brain and spinal cord contain connexin-36 but not connexin-32 or connexin-43. Proc Natl Acad Sci USA 97:7573-7578.
38. Rash JE, Yasumura T, Dudek FE, Nagy JI. 2001. Cell-specific expression of connexins and evidence of restricted gap junctional coupling between glial cells and between neurons. J Neurosci 21:1983-2000.
39. Shapovalov AI. 1980. Interneuronal synapses with electrical, dual and chemical mode of transmission in vertebrates. Neuroscience 5:1113-1124.
40. Sloper JJ, Powell TP. 1978. Gap junctions between dendrites and somata of neurons in the primate sensori-motor cortex. Proc R Soc Lond B Biol Sci 203:39-47.
41. Sohl G, Degen J, Teubner B, Willecke K. 1998. The murine gap junction gene connexin36 is highly expressed in mouse retina and regulated during brain development. FEBS Lett 428:27-31.
42. Sotelo C, Palay SL. 1970. The fine structure of the later vestibular nucleus in the rat. II. Synaptic organization. Brain Res 18:93-115.
43. Sotelo C, Llinas R, Baker R. 1974. Structural study of inferior olivary nucleus of the cat: morphological correlates of electrotonic coupling. J Neurophysiol 37:541-559.
44. Srinivas M, Rozental R, Kojima T, Dermietzel R, Mehler M, Condorelli DF, Kessler JA, Spray DC. 1999. Functional properties of channels formed by the neuronal gap junction protein connexin36. J Neurosci 19:9848-9855.
45. Steriade M, Jones EG, McCormick DA. 1997. Thalamus. Amsterdam: Elsevier.
46. Tamas G, Buhl EH, Lorinez A, Somogyi P. 2000. Proximally targeted GABAergic synapses and gap junctions synchronize cortical interneurons. Nat Neurosci 3:366-371.