The Statistical Basis of Laboratory Data Normalization

Drug Information Journal

Volumn 37, Issue 1, 2003, Pages 101-107

  Karvanen, Juha ^a  

^a AALTO UNIVERSITY   (Finland)

Author keywords

Location scale family; Normalization; Reference limits; Reference range; Scale family

Indexed keywords

ARTICLE; BIOINFORMATICS; BLOOD CHEMISTRY; CLINICAL LABORATORY; DRUG RESEARCH; MATHEMATICAL MODEL; NORMAL VALUE; PRIORITY JOURNAL; REFERENCE VALUE; STANDARDIZATION;

EID: 0142153222     PISSN: 00928615     EISSN: None     Source Type: Journal    
DOI: 10.1177/009286150303700112     Document Type: Article

References (5)

1. European Agency for the Evaluation of Medical Products. ICH Topic E9, Statistical Principles for Clinical Trials. London, United Kingdom: European Agency for the Evaluation of Medical Products; 1998.
2. Chuang-Stein C. Summarizing laboratory data with different reference ranges in multi-center clinical trials. Drug Inf J. 1992;26(1):77-84.
3. Chuang-Stein C. Some issues concerning the normalization of laboratory data based on reference ranges. Drug Inf J. 2001;35(1):153-156.
4. Huang J, Brunelle R. A nonparametric method for combining multilaboratory data. Drug Inf J. 2002;36(2):395-406.
5. Sogliero-Gilbert G, Mosher K, Zubkoff L. A procedure for the simplification and assesment of lab parameters in clinical trials. Drug Inf J. 1986;20:279-296.