The effect of metronidazole in treating human fascioliasis

Medical Science Monitor

Volumn 9, Issue 10, 2003, Pages

  Mansour Ghanaei, Fariborz ^a   Shafaghi, Afshin ^a   Fallah, Mohammadsadegh ^a  

^a GUILAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Human fascioliasis; Metronidazole; Triclabendazole

Indexed keywords

METRONIDAZOLE;

ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG EFFICACY; DRUG SAFETY; FASCIOLIASIS; FEMALE; HEADACHE; HUMAN; IRAN; MALE; NAUSEA; OPEN STUDY; TASTE DISORDER;

ADULT; ANTHELMINTICS; ANTITRICHOMONAL AGENTS; BENZIMIDAZOLES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FASCIOLIASIS; FECES; FEMALE; HUMANS; MALE; METRONIDAZOLE; TIME FACTORS;

EID: 0142153145     PISSN: 12341010     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (23)

1. Tolan RW, Fennelly G: Fascioliasis. eMedicine Journal, April 15 2002; 3(4). [Available at: http://www.emedicine.com/ped/topic760.htm; last updated: April 15 2002]
2. Savioli L, Chitsulo L, Montresor A: New opportunities for control of fascioliasis. Bulletin of the WHO, 1999; 77(4): 300 [Available at: http://www.who.org/editorials/issue4/editorial2.htm]
3. Yadegari D, Sarshad A: A Survey of effects of praziquantel, bithionol and triclabendazole for the treatment of human fascioliasis in Guilan province, Iran. Proceedings Abstracts of the first Iranian Symposium on parasitic diseases, 1990; December 11-13, Rasht, Iran
4. Ortiz P, Cabrera M, Jave J et al: Human fascioliasis: prevalence and treatment in a rural area of Peru. Infect Dis Rev, 2000; 2(1): 42-46
5. Arafa MM, Lashen AH: A case of human fascioliasis in Qualyobia Governorate. J Egypt Soc Parasitol, 1993; 23(2): 599-600
6. Nik-Akhtar B, Tabibi V: Metronidazole in Fascioliasis, Report of four cases. J Trop Med Hyg, 1977; 80: 179-180
7. Hammouda NA, el-Mansoury ST, el-Azzouni MZ et al: Therapeutic effect of triclabendazole in patients with fascioliasis in Egypt. A preliminary study. J Egypt Soc Parasitol, 1995; 25(1): 137-43
8. Osman MM, Helmy M, Megehed MA: Studies of human fascioliasis in Egypt. Some lipid parameters before and after treatment. J Egypt Soc Parasitol, 1995; 25(3): 769-72
9. Stitt AW, Fairweather I: The effect of the sulphoxide metabolite of triclabendazole (Fasinex) on the tegument of mature and immature stages of the liver fluke, Fasciola hepatica. Parasitology, 1994; 108(pt 5): 555-67
10. Fairweather I, Boray JC. Fasciolicides: efficacy, actions, resistance and its management. Vet J, 1999; 158(2): 81-112
11. Moll L, Gaasenbeck CP, Vellema P et al: Resistance of fasciola hepatica against triclabendazole in cattle and sheep in the Netherlands, Vet Parasitol, 2000; 24; 91(1-2): 153-8
12. Thomas I, Coles GC, Duffus K: Triclabendazole-resistant fasciola hepatica in southwest wales. Vet- Rec, 2000; 146(7): 200
13. Hof H: Antimicrobial therapy with nitroheterocyclie compounds, for example, metronidazole and nitrofurantoin. Immun Infekt. 1988; 16(6): 220-5
14. Cosar C, Ganter P, Julou L: Etude expérimentale du métronidazole. 8823 R.P. activitiés trichomonacide et amoebicide. Toxicicité et propriétés pharmacologiques générales. Presse Med, 1961; 69: 1069-72
15. Jokipii L, Jokipii AMM: In vitro susceptibility of Giardia Lamblia trophozoites to metronidazole and tinidazole. J Infect Dis, 1980; 141: 317-325
16. Leslie T, Webster Jr: Drugs used in the chemotherapy of protozoal infections. In: Gilman AG et al. [eds.]: Goodmans and Gilman's the pharmacological basis of therapeutics, 8th edit Maxwell. Macmillan International Editions. 1991 P: 1002-1005
17. Muller R: Guinea worm disease: epidemiology, control, and treatment. Bull WHO, 1979; 57(5): 683-9
18. Padonu KO: A controlled trial with metronidazole in the treatment of dracontiasis in Nigeria. Am J Trop Med Hyg, 1973; 22: 42-44
19. Adams GE, Stratford IJ, Wallace IG et al: Toxicity of nitrocompounds towards hypoxic mammalian cells in vitro; dependence on reduction potential. J Natl Cancer Inst, 1980; 64: 555-560
20. Mc-Gonigle S, Curley GP, Dalton JP: Cloning of peroxiredoxin, a novel antioxidant enzyme, from the helminth parasite Fasciola hepatica. Parasitology, 1997; 115(pt 1): 101-4
21. Mas-Coma S: Human fascioliasis. A review of pathology, symptomatology, clinical manifestation, diagnosis and treatment. Contnts included in the conference presented on 2001, June 11, Guilan province, Iran
22. Apt W, Aguilera X, Vega F et al: Treatment of human chronic fascioliasis with triclabendazole: drug efficacy and serologic response Am J Trop Med Hyg, 1995, 52(6): 532-5
23. Roe FJC: Metronidazole: review of uses and toxicity. J Antimicrob Chemother, 1977; 3: 205-212