Kaposi sarcoma in HIV patients. Response to antiretroviral treatment and chemotherapy;Sarcoma de Kaposi y VIH: Tratamiento antirretroviral y quimioterapia en 32 pacientes

Revista Medica de Chile

Volumn 131, Issue 5, 2003, Pages 483-490

  Lasso B, Martín ^a   Pérez G, Jorge ^a   Noriega R, Luis ^a   Malebrán R, Andrea ^b   Espinoza V, Susana ^b  

^a HOSPITAL DR SÓTERO DEL RÍO   (Chile)

^b Enfermera Universitaria ^*

Author keywords

Drug therapy; Drug therapy, combination; HIV infections; Sarcoma, Kaposi

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIRETROVIRUS AGENT; BLEOMYCIN; CD4 ANTIGEN; DIDANOSINE; EFAVIRENZ; INDINAVIR; LAMIVUDINE; NELFINAVIR; NEVIRAPINE; RITONAVIR; SAQUINAVIR; STAVUDINE; VINCRISTINE; VIRUS RNA; ZALCITABINE; ZIDOVUDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; RNA DIRECTED DNA POLYMERASE INHIBITOR;

ADULT; ANEMIA; CANCER CHEMOTHERAPY; CANCER PATIENT; CELL COUNT; COHORT ANALYSIS; COLORECTAL DISEASE; CONTROLLED STUDY; DEATH; DRUG RESPONSE; FEMALE; GASTROINTESTINAL SYMPTOM; HEALTH CENTER; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; KAPOSI SARCOMA; LUNG TUBERCULOSIS; LYMPHEDEMA; MAJOR CLINICAL STUDY; MALE; PNEUMONIA; PUBLIC HOSPITAL; REMISSION; RETINITIS; RETROSPECTIVE STUDY; REVIEW; VIRUS LOAD; AIDS RELATED COMPLEX; ARTICLE; CD4 LYMPHOCYTE COUNT; DRUG COMBINATION; MIDDLE AGED; MORTALITY; PATHOLOGY; TIME;

ADULT; AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTI-HIV AGENTS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CD4 LYMPHOCYTE COUNT; DRUG THERAPY, COMBINATION; HIV INFECTIONS; HUMANS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; REVERSE TRANSCRIPTASE INHIBITORS; SARCOMA, KAPOSI; TIME FACTORS; VIRAL LOAD;

EID: 0142152332     PISSN: 00349887     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (26)

1. JONES JL, HANSON DL, DWORKIN MS, WARD JW, JAFFE HW. Effect of antiretroviral therapy on recent trends in selected cancers among HIV-infected persons. Adult/adolescent spectrum of HIV disease project group. J Acquir Immune Defic Syndr Hum Retrovirol 1999; 21(suppl 1): S11-S17.
2. O'BRIEN TR, KEDES D, GANEM D, MACRAE DR, ROSENBERG PS, MOLDEN J ET AL. Evidence for concurrent epidemics of human herpesvirus 8 and human immunideficiency virus type 1 in US homosexual men: rates, risk factors and relationship to Kaposi's sarcoma. J Infect Dis 1999; 180: 1010-7.
3. RIZZIERI DA, LIU J, TRAWEECK ST, MIRALLES G. Clearance of HHV-8 from peripheral blood mononuclear cells with a portease inhibitor. Lancet 1997; 349: 775-6.
4. BLUM L, PELLET C, AGBALIKA F, BLANCHARD G, MOREL P, CALVO F ET AL. Complete remission of AIDS-related Kaposi's sarcoma associated with undetectable Human Herpes Virus 8 sequences during anti-HIV protease therapy. AIDS 1997; 11: 1653-4.
5. MURPHY M, AMSTRONG D, SEPKOWITZ KA, AHKAMI RN, MYSKOWSKI PL. Regression of AIDS related Kaposi's sarcoma following treatment with HIV-1 protease inhibitor. AIDS 1997; 11: 261-2.
6. WIT FW, SOL CJ, RENWICK N, ROOS MT, PALS ST, VAN LEEUWEN R ET AL. Regression of AIDS-related Kaposi's sarcoma associated with clearance of human herpes virus 8 from peripheral blood mononuclear cells following initiation of antiretroviral therapy. AIDS 1998; 12: 218-9.
7. DUPONT C, VASSEUR E, BEAUCHET A, AEGERTER P, BERTHÉ H, TRUCHIS P ET AL. Long-term efficacy on Kaposi's sarcoma of highly active antiretroviral therapy in a cohort of HIV-positive patients. AIDS 2000; 14: 987-93.
8. KROWN SE, METROKA C, WERNZ JC. Kaposi's sarcoma in the acquired immune deficiency syndrome: proposal for uniform evaluation, response and staging criteria. J Clin Oncol 1989; 7: 1201-7.
9. FRIEDMAN-KIEN AE, LAUBENSTEIN L, MARMOR M, HYMAS K, GREEN J, RAGAZ A ET AL. Kaposi sarcoma and Pneumocystis pneumonia among homosexual men, New York city and California. MMWR Morb Mortal Wkly Rep 1981; 30: 305-8.
10. CHANG Y, CESARMAN P, PESSIN MS, LEE F, CULPEPPER J, KNOWLES DM ET AL. Identification of herpesvirus like DNA sequences in AIDS associated Kaposi's sarcoma. Science 1994; 266: 1865-9.
11. GAO SJ, KINGSLEY L, HOOVER DR, SPIRA TJ, RINALDO CR, SAAH A ET AL. Seroconversion to antibodies against Kaposi's sarcoma, associated herpesvirus related latent nuclear antigens before to development of Kaposi's sarcoma. N Engl J Med 1996; 335: 233-41.
12. MARTIN JN, GANEM DE, OSMOND DH, PAGE-SHAFER KA, MACRAE D, KEDES DH. Sexual transmision and the natural history of human herpes virus 8 infection. N Engl J Med 1998; 338: 948-54.
13. DUKERS N, RENWICK N, PRINS M, GESKUS R, SCHULZ T, WEVERLING GJ ET AL. Risk factors for human herpesvirus 8 seropositivity and seroconversion in a cohort of homosexual men. Am J Epidemiol 2000; 151: 213-24.
14. MIHALCEA AM, SMITH L, MONINI P, SGADARI C, ENSOLI B, GILL P. Treatment update for AIDS-related Kaposi's sarcoma. AIDS 1999; 13: S215: 25.
15. DEZUBE BJ. New therapies for the treatment of AIDS-related Kaposi sarcoma. Curr Opin Oncol 2000; 12: 445-9.
16. MITUSAYASU RT. Update on the pathogenesis and treatment of Kaposi's sarcoma. Curr Opin Oncol 2000; 12: 174-80.
17. FINGLETON B, MATRISIAN L. Matrix metalloproteinases as targets for therapy in Kaposi sarcoma. Curr Opin Oncol 2001; 13: 368-73.
18. VOGEL J, HINRCHS SH, REYNOLS RK, LUCIW PA, JAY G. The HIV tat gene induces dermal lesions resembling Kaposi's sarcoma in transgenic mice. Nature 1988; 355: 606-11.
19. ENSOLI B, BARILLARI G, SALAHUDDIN RK, GALLO RC, WONG-STAAL F. Tat protein of HIV-1 stimulates growth of AIDS Kaposi's sarcoma-derived cells. Nature 1990; 345: 84-6.
20. ENSOLI B, GENDELMAN R, MARKHAM P, FIORELLI V, COLOMBINI S, RAFFELD M ET AL. Synergic between basic fibroblast growth factor and HIV Tat protein in induction of Kaposi's sarcoma development. Nature 1994; 371: 674-80.
21. FRIEDMAN-KEIN AE, SALTZMAN BR, CAO YZ, NESTOR MS, MIRABILE M, LI JJ ET AL. Kaposi's sarcoma in HIV negative homosexual men. Lancet 1990; 335b: 168-9.
22. GILL P, TSAI Y, RAO AP, JONES P. Clonality in Kaposi's sarcoma. N Engl J Med 1997; 337: 570-1.
23. MEDVECZKY MM, HORVATH E, LUND T, MEDVECZKY PG. In vitro antiviral drug sensitivity of the Kaposi's sarcoma associated herpesvirus. AIDS 1997; 11: 1327: 32.
24. MOCROFT A, YOULE M, GAZZARD B, MORCINEK J, HALAI R, PHILLIPS AN. Antiherpesvirus treatment and risk of Kaposi's sarcoma in HIV infection. Royal Free/Chelsea and Westminster Hospitals Collaborative Group. AIDS 1996; 10: 1101-5.
25. GILL PS, AKIL B, COLLETI P, RARICK M, LOUREIRO C, BERNSTEIN-SINGER M ET AL. Pulmonary Kaposi's sarcoma. Clinical findings and results of therapy. Am J Med 1989; 87: 57-61.
26. GILL PS, RARICK M, MCCUTCHAN JA, SLATER L, PARKER B, MUCHMORE E ET AL. Systemic treatment of AIDS related Kaposi's sarcoma: results of a randomized trial. Am J Med 1991; 90: 427-33.