Upper airway surface tension: Is it a significant cause of airflow obstruction during sleep?

Journal of Applied Physiology

Volumn 95, Issue 5, 2003, Pages 1759-1760

  Schwartz, Alan R ^a   Schneider, Hartmut ^a   Smith, Philip L ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LUNG SURFACTANT;

AIRWAY DYNAMICS; EDITORIAL; HUMAN; PRIORITY JOURNAL; RESPIRATORY EPITHELIUM; SLEEP APNEA SYNDROME; SURFACE PROPERTY; SURFACE TENSION; UPPER RESPIRATORY TRACT OBSTRUCTION;

EID: 0142149332     PISSN: 87507587     EISSN: None     Source Type: Journal    
DOI: 10.1152/japplphysiol.00747.2003     Document Type: Editorial

References (19)

1. Ayappa I and Rapoport DM. The upper airway in sleep: physiology of the pharynx. Sleep Med Rev 7: 9-33, 2003.
2. Boudewyns A, Punjabi N, Van de Heyning PH, De Backer WA, O'Donnell CP, Schneider H, Smith PL, and Schwartz AR. Abbreviated method for assessing upper airway function in obstructive sleep apnea. Chest 118: 1031-1041, 2000.
3. Gleadhill IC, Schwartz AR, Schubert N, Wise RA, Permutt S, and Smith PL. Upper airway collapsibility in snorers and in patients with obstructive hypopnea and apnea. Am Rev Respir Dis 143: 1300-1303, 1991.
4. Gold AR, Marcus CL, Dipalo F, and Gold MS. Upper airway collapsibility during sleep in upper airway resistance syndrome. Chest 121: 1531-1540, 2002.
5. Gold AR and Schwartz AR. The pharyngeal critical pressure. The whys and hows of using nasal continuous positive airway pressure diagnostically. Chest 110: 1077-1088, 1996.
6. Isono S, Remmers JE, Tanaka A, Sho Y, Sato J, and Nishino T. Anatomy of pharynx in patients with obstructive sleep apnea and normal subjects. J Appl Physiol 82: 1319-1326, 1997.
7. Kimoff RJ, Sforza E, Champagne V, Ofiara L, and Gendron D. Upper airway sensation in snoring and obstructive sleep apnea. Am J Respir Crit Care Med 164: 250-255, 2001,
8. Kirkness JP, Amis TC, Wheatley JR, and Christenson HK. Determining the surface tension of microliter amounts of liquid. J Colloid Interface Sci 232: 408-409, 2000.
9. Kirkness JP, Christenson HK, Garlick SR, Parikh R, Kairaitis K, Wheatley JR, and Amis TC. Decreased surface tension of upper airway mucosal lining liquid increases upper airway patency in anaesthetised rabbits. J Physiol 547: 603-611, 2003.
10. Kirkness JP, Eastwood PR, Szollosi I, Platt PR, Wheatley JR, Amis TC, and Hillman DR. Effect of surface tension of mucosal lining liquid on upper airway mechanics in anesthetized humans. J Appl Physiol 95: 357-363, 2003.
11. Kirkness JP, Madronio M, Stavrinou R, Wheatley JR, and Amis TC. Relationship between surface tension of upper airway lining liquid and upper airway collapsibility during sleep in obstructive sleep apnea hypopnea syndrome. J Appl Physiol 95: 1761-1766, 2003.
12. Mezzanotte WS, Tangel DJ, and White DP. Waking genioglossal electromyogram in sleep apnea patients versus normal controls (a neuromuscular compensatory mechanism). J Clin Invest 89: 1571-1579, 1992.
13. Miki H, Hida W, Kikuchi Y, Chonan T, Satoh M, Iwase N, and Takishima T. Effects of pharyngeal lubrication on the opening of obstructed upper airway. J Appl Physiol 72: 2311-2316, 1992.
14. Neill AM, Angus SM, Sajkov D, and McEvoy RD. Effects of sleep posture on upper airway stability in patients with obstructive sleep apnea. Am J Respir Crit Care Med 155:199-204, 1997.
15. Paulsen FP, Steven P, Tsokos M, Jungmann K, Muller A, Verse T, and Pirsig W. Upper airway epithelial structural changes in obstructive sleep-disordered breathing. Am J Respir Crit Care Med 166: 501-509, 2002.
16. Remmers JE, deGroot WJ, Sauerland EK, and Anch AM. Pathogenesis of upper airway occlusion during sleep. J Appl Physiol 44: 931-938, 1978.
17. Rowley JA, Permutt S, Willey S, Smith PL, and Schwartz AR. Effect of tracheal and tongue displacement on upper airway airflow dynamics. J Appl Physiol 80: 2171-2178, 1996.
18. Van der Touw T, Crawford AB, and Wheatley JR. Effects of a synthetic lung surfactant on pharyngeal patency in awake human subjects. J Appl Physiol 82: 78-85, 1997.
19. Watanabe T, Isono S, Tanaka A, Tanzawa H, and Nishino T. Contribution of body habitus and craniofacial characteristics to segmental closing pressures of the passive pharynx in patients with sleep-disordered breathing. Am J Respir Crit Care Med 165: 260-265, 2002.