The Region between Transmembrane Domains 1 and 2 of the Reduced Folate Carrier Forms Part of the Substrate-binding Pocket

Journal of Biological Chemistry

Volumn 278, Issue 42, 2003, Pages 40867-40876

  Flintoff, Wayne F ^a   Williams, Frederick M R ^c   Sadlish, Heather ^b  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOLOGICAL MEMBRANES; PROTEINS; SUBSTRATES;

TRANSMEMBRANE SEGMENTS;

BIOCHEMISTRY;

ALANINE; BIOTIN DERIVATIVE; BIOTIN MALEIMIDE; CARRIER PROTEIN; CYSTEINE; FOLIC ACID; MEMBRANE PROTEIN; METHOTREXATE; PROTEIN FOLATE CARRIER; STREPTOLYSIN O; UNCLASSIFIED DRUG;

ARTICLE; BIOTINYLATION; CONTROLLED STUDY; CYTOSOL; ENZYME BINDING; ENZYME SUBSTRATE COMPLEX; HAMSTER; HUMAN; MEMBRANE PERMEABILITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN MODIFICATION;

ALANINE; AMINO ACID SEQUENCE; ANIMALS; BACTERIAL PROTEINS; BIOTIN; BIOTINYLATION; CARRIER PROTEINS; CELL MEMBRANE; CRICETINAE; CYSTEINE; CYTOSOL; FOLIC ACID; GREEN FLUORESCENT PROTEINS; KINETICS; LUMINESCENT PROTEINS; MEMBRANE TRANSPORT PROTEINS; METHOTREXATE; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT FUSION PROTEINS; RNA; STREPTOLYSINS;

CRICETINAE;

EID: 0142135129     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M302102200     Document Type: Article

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