Pneumonia due to Chlamydia pneumoniae in Children: Epidemiology, Diagnosis, and Treatment

Pediatric Pulmonology

Volumn 36, Issue 5, 2003, Pages 384-390

  Hammerschlag, Margaret R ^a  

^a SUNY Downstate Medical Center   (United States)

Author keywords

Chlamydia pneumonia; Pneumonia

Indexed keywords

AZITHROMYCIN; CIPROFLOXACIN; CLARITHROMYCIN; DOXYCYCLINE; ERYTHROMYCIN; GATIFLOXACIN; LEVOFLOXACIN; MOXIFLOXACIN; OFLOXACIN; ROXITHROMYCIN; TELITHROMYCIN;

ARTICLE; BACTERIAL PNEUMONIA; CHILD; CHLAMYDOPHILA PNEUMONIAE; CLINICAL FEATURE; HUMAN; INFANT; LEGIONELLA; MYCOPLASMA PNEUMONIAE; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT INFECTION; SERODIAGNOSIS; STREPTOCOCCUS PNEUMONIAE;

ADOLESCENT; ANTI-BACTERIAL AGENTS; ANTIBODIES, BACTERIAL; CHILD; CHILD, PRESCHOOL; CHLAMYDOPHILA INFECTIONS; CHLAMYDOPHILA PNEUMONIAE; DNA, BACTERIAL; HUMANS; INFANT; INFANT, NEWBORN; MACROLIDES; PNEUMONIA, BACTERIAL; QUINOLONES; SENSITIVITY AND SPECIFICITY; TETRACYCLINES;

EID: 0142126270     PISSN: 87556863     EISSN: None     Source Type: Journal    
DOI: 10.1002/ppul.10326     Document Type: Article

References (53)

1. Grayston JT, Kuo C-C, Campbell LA, Wang SP. Chlamydia pneumoniae sp. nov. for Chlamydia sp. strain TWAR. Int J Syst Bacteriol 1989;39:88-90.
2. Fukushi H, Hirai K. Chlamydia pecorum: The fourth species of genus Chlamydia. Microbiol Immunol 1993;37:516-522.
3. Everett KDE, Bush RM, Anderson AA. Emended description of the order Chlamydiales, proposal of Parachlamydiaceae fam. nov. and Simkaniaceae fam. nov., each containing one monotypic genus, revised taxonomy of the family Chlamydiaceae, including a new genus and five new species, and standards for identification of organisms. Int J Syst Bacteriol 1999;49:425-440.
4. Kalman S, Mitchell W, Marathe R, Lammel C, Fan J, Hyman RW, Olinger L, Grimwood J, Davies RW, Stephens RS. Comparative genomes of Chlamydia pneumoniae and C. trachomatis. Nat Gen 1999;21:385-389.
5. Rockey DD, Lenart J, Stephens RS. Genome sequencing and our understanding of chlamydiae. Infect Immun 2000;68:5473-5479.
6. Beatty WL, Morrison RP, Byrne GL. Persistent chlamydiae: from cell culture to a paradigm for chlamydial pathogenesis. Microbiol Rev 1994;58:689-699.
7. Campbell LA, Kuo C-C, Grayston JT. Characterization of the new Chlamydia agent, TWAR, as a unique organism by restriction endonuclease analysis and DNA-DNA hybridization. J Clin Microbiol 1987;25:1911-1916.
8. Carter MW, Sah AM, Treharne JD, Treharne JD, Ward ME, Clarke IN. Nucleotide sequence and taxonomic value of the major outer membrane protein gene of Chlamydia pneumoniae IOL-207. J Gen Microbiol 1991;137:465-475.
9. Meijer A, Morré SA, Van Den Brule AJC, Savelkoul PHM, Ossewaarde JM. Genomic relatedness of Chlamydia isolates determined by amplified fragment length polymorphism analysis. J Bacteriol 1999;181:4469-4-475.
10. Hyman CL, Augenbraun MH, Roblin PM, Schachter J, Hammerschlag MR. Asymptomatic respiratory tract infection with Chlamydia pneumoniae. J Clin Microbiol 1991;29:2082-2083.
11. Falsey AR, Walsh EE. Transmission of Chlamydia pneumoniae. J Infect Dis 1993;168:493-496.
12. Theunissen HJJ, Lemmens-Den Toom NA, Burggraaf A, Stolz E, Michel MF. Influence of temperature and relative humidity on the survival of Chlamydia pneumoniae in aerosols. Appl Environ Microbiol 1993;59:2589-2593.
13. Hammerschlag MR, Chirgwin K, Roblin PM, Gelling M, Dumornay W, Man del L, Smith P, Schachter J. Persistent infection with Chlamydia pneumoniae following acute respiratory illness. Clin Infect Dis 1992;14:178-182.
14. Kleemola M, Saikku P, Visakorpi R, Wang SP, Grayston JT. Epidemics of pneumonia caused by TWAR, a new Chlamydia organism, in military trainees in Finland. J Infect Dis 1988;157:230-236.
15. Yamazaki T, Nakada H, Sakurai N, Kuo CC, Wang SP, Grayston JT. Transmission of Chlamydia pneumoniae in young children in a Japanese family. J Infect Dis 1990;162:390-1392.
16. Grayston JT, Campbell LA, Kuo CC, Mordhorst CH, Saikku P, Thom DH, Wang SP. A new respiratory tract pathogen: Chlamydia pneumoniae strain TWAR. J Infect Dis 1990;161:618-625.
17. Saikku P, Ruutu P, Leinonen M, Panelius J, Tupasi TE, Grayston JT. Acute lower-respiratory-tract infection associated with chlamydial TWAR antibody in Filipino children. J Infect Dis 1988;158:1095-1097.
18. Chirgwin K, Roblin PM, Gelling M, Hammerschlag MR, Schachter J. Infection with Chlamydia pneumoniae in Brooklyn. J Infect Dis 1991;163:757-761.
19. Forgie IM, O'Neill KP, Lloyd-Evans N, Leinonen M, Saikku P, Whittle HC, Greenwood BM. Etiology of acute lower respiratory tract infections in Gambian children. II. Acute lower respiratory tract infection in children ages one to nine years presenting at the hospital. Pediatr Infect Dis J 1991;10:42-47.
20. Yeung SM, McLeod K, Wang SP, Grayston JT, Wang E. Lack of evidence for Chlamydia pneumoniae infection in infants with acute lower respiratory tract disease. Eur J Clin Microbiol Infect Dis 1993;12:850-853.
21. Herrmann SB, Salih MAM, Yousif BE. Chlamydial etiology of acute lower respiratory tract infections in children in the Sudan. Acta Paediatr 1994;83:169-172.
22. Jantos CA, Wienpahl B, Schiefer HG, Wagner F, Hegemann JH. Infection with Chlamydia pneumoniae in infants and children with acute lower respiratory tract disease. Pediatr Infect Dis J 1995;14:117-122.
23. Block S, Hedrick J, Hammerschlag MR, Cassell GH. Mycoplasma pneumoniae and Chlamydia pneumoniae in pediatric community-acquired pneumonia: comparative efficacy and safety of clarithromycin vs. erythromycin ethylsuccinate. J Pediatr Infect Dis 1995;14:471-477.
24. Harris J-A, Kolokathis A, Campbell M, Cassell GH, Hammerschlag MR. Safety and efficacy of azithromycin in the treatment of community acquired pneumonia in children. Pediatr Infect Dis J 1998;17:865-871.
25. Heiskanen-Kosma T, Korppi M, Jokinen C, Kurki S, Heiskanen L, Juvonen H, Kallinen S, Stén M, Tarkianinen A, Rnnberg P-R, Kleemola M, Mäkëla H, Leinonen M. Etiology of childhood pneumonia: serologic results of a prospective, population-based study. Pediatr Infect Dis J 1998;17:986-991.
26. Wubbel L, Muniz L, Ahmed A, Trujillo M, Carrubelli C, McCoig C, Abramo T, Leinonen M, McCracken GH. Etiology and treatment of community-acquired pneumonia in ambulatory children. Pediatr Infect Dis J 1999;18:98-104.
27. Dean D, Roblin PM, Mandel L, Schachter J, Hammerschlag M. Molecular evaluation of serial isolates from patients with persistent Chlamydia pneumoniae infection. In: Stephens RS, Byrne GI, Christiansen GI, Clarke IN, Grayston JT, Rank RG, Ridgway GL, Saikku P, Schachter J, Stamm WE, editors. Chlamydial infections. Proceedings of the Ninth International Symposium on Human Chlamydial Infection. San Francisco: UCSF; 1998. p 219-222.
28. Emre U, Roblin PM, Gelling M, Dumornay W, Rao M, Hammerschlag MR, Schachter J. The association of Chlamydia pneumoniae infection and reactive airway disease in children. Arch Pediatr Adolesc Med 1994;148:727-731.
29. Block S, Hammerschlag MR, Hedrick J, Tyler R, Smith A, Roblin PM, Gaydos C, Pham D, Quinn TC, Palmer R, McCarty J. Chlamydia pneumoniae in acute otitis media. Pediatr Infect Dis J 1997;16:858-862.
30. Gnarpe J, Gnarpe H, Sundelof B. Endemic prevalence of Chlamydia pneumoniae in subjectively healthy persons. Scand J Infect Dis 1991;23:387-388.
31. Hyman CL, Roblin PM, Gaydos CA, Quinn TC, Schachter J, Hammerschlag MR. Prevalence of asymptomatic nasopharyngeal carriage of Chlamydia pneumoniae in subjectively healthy adults: assessment by polymerase chain reaction-enzyme immunoassay and culture. Clin Infect Dis 1995;20:1174-1178.
32. Berdal BP, Scheel O, Ogaard AR, Hoel T, Gutteberg TJ, Anestad G. Spread of subclinical Chlamydia pneumoniae infection in a closed community. Scand J Infect Dis 1992;24:431-436.
33. Augenbraun MH, Roblin PM, Mandel LJ, Hammerschlag MR, Schachter J. Chlamydia pneumoniae pneumonia with pleural effusion: diagnosis by culture. Am J Med 1991;91:437-438.
34. Miller ST, Hammerschlag MR, Chirgwin K, Rao SP, Roblin PM, Gelling M, Stilerman T, Schachter J, Cassell G. The role of Chlamydia pneumoniae in acute chest syndrome of sickle cell disease. J Pediatr 1991;118:30-33.
35. Vichinsky EP, Neumayr LD, Earles AN, Williams R, Lennette ET, Dean D, Nickerson B, Orringer E, McKie V, Bellevue R, Daeschner C, Manci EA. Causes and outcomes of the acute chest syndrome in sickle cell disease. N Engl J Med 2000;342:1855-1865.
36. Roblin PM, Dumornay W, Hammerschlag MR. Use of HEp-2 cells for improved isolation and passage of Chlamydia pneumoniae. J Clin Microbiol 1992;30:1968-1971.
37. Grayston JT, Aldous MB, Easton A, Wang SP, Kuo CC, Campbell LA, Altman J. Evidence that Chlamydia pneumoniae causes pneumonia and bronchitis. J Infect Dis 1993;168:1231-1235.
38. Kutlin A, Roblin P, Hammerschlag MR. Antibody response to Chlamydia pneumoniae infection in children with respiratory illness. J Infect Dis 1998;177:720-724.
39. Iijima Y, Miyashita N, Kishimoto T, Kanamoto Y, Soejima K, Matsumoto A. Characterization of Chlamydia pneumoniae species-specific proteins immunodominant in humans. J Clin Microbiol 1994;32:583-588.
40. Maurin M, Eb F, Etienne J, Raoult D. Serologic cross-reactions between Bartonella and Chlamydia species: implications for diagnosis. J Clin Microbiol 1997;35:2283-2287.
41. Jackson LA, Cherry JD, Wang SP, Grayston JT. Frequency of serological evidence of Bordetella infections and mixed infections with other respiratory pathogens in university students with cough illnesses. Clin Infect Dis 2000;31:3-6.
42. Ochiai Y, Fukushi H, Yan C, Yamaguchi T, Hirai K. Comparative analysis of the putative amino acid sequences of chlamydial heat shock protein 60 and Escherichia coli GroEL. J Vet Med Sci 2000;62:941-945.
43. Harkonen T, Puolakkainen M, Sarvas M, Airaksinen U, Hovi T, Roivanen M. Picornavirus proteins share antigenic determinants with heat shock proteins 60/65. J Med Virol 2000;62:383-391.
44. Peeling R, Wang S, Grayston JT. Chlamydia pneumoniae serology: interlaboratory variation in microimmunofluorescence assay results. J Infect Dis [Suppl] 2000;181:426-429.
45. Dowell SF, Peeling RW, Boman J, Carlone GM, Fields BS, Guamer J, Hammerschlag MR, Jackson LA, Kuo CC, Maass M, Messmer TO, Talkington DF, Tondella ML, Zaki SR. Standardizing Chlamydia pneumoniae assays: recommendations from the Centers for Disease Control and Prevention (USA) and the Laboratory Centre for Disease Control (Canada). Clin Infect Dis 2001;33:492-503.
46. Boman J, Gaydos CA, Quinn TC. Molecular diagnosis of Chlamydia pneumoniae infection. J Clin Microbiol 1999;37:3791-3799.
47. Apfalter PF, Blasi F, Boman J, Gaydos CA, Kundi M, Maass M, Makristathis A, Meijer A, Nadrchal R, Persson K, Rotter ML, Tong CYW, Stanek G, Hirschl AM. Multicenter comparison trial of DNA extraction methods and PCR assays for detection of Chlamydia pneumoniae in endarterectomy specimens. J Clin Microbiol 2001;39:519-524.
48. Apfalter P, Assadian O Blasi F, Boman J, Gaydos CA, Kundi M, Makristathis A, Nehr M, Rotter ML, Hirschl AM. Reliability of nested PCR for detection of Chlamydia pneumoniae DNA in atheromas: results from a multicenter study applying standardized protocols. J Clin Microbiol 2002;40:4428-4434.
49. Hammerschlag MR, Roblin PM, Bébéar CM. Activity of telithromycin, a new ketolide antimicrobial, against atypical and intracellular respiratory tract pathogens. J Antimicrob Chemother 2002;48:25-31.
50. Hammerschlag MR, Roblin PM. Microbiologic efficacy of levofloxacin for the treatment of community-acquired pneumonia due to Chlamydia pneumoniae. Antimicrob Agents Chemother 2000;44:1409.
51. Hammerschlag MR, Roblin PM. Microbiologic efficacy of moxifloxacin for the treatment of community-acquired pneumonia due to Chlamydia pneumoniae. Int J Antimicrob Agents 2000;15:149-152.
52. Roblin PM, Montalban G, Hammerschlag MR. Susceptibility to clarithromycin and erythromycin of isolates of Chlamydia pneumoniae from children with pneumonia. Antimicrob Agents Chemother 1994;38:1588-1589.
53. Roblin PM, Hammerschlag MR. Microbiologic efficacy of azithromycin and susceptibility to azithromycin of isolates of Chlamydia pneumoniae from adults and children with community acquired pneumonia. Antimicrob Agents Chemother 1998;42:194-196.